Metabolic engineering of Saccharomyces cerevisiae for neoxanthin production [0.03%]
用于合成新黄素的大肠杆菌代谢工程
Natalia Arenas,Vicente F Cataldo,Eduardo Agosin
Natalia Arenas
Background: Xanthophylls, a subclass of oxygenated carotenoids, are highly valued for their wide range of applications in the food and pharmaceutical industries, particularly due to their antioxidant properties and potent...
A novel strategy for synthetic microbial community conversion of liquid pig manure into microbial fertilizer [0.03%]
一种合成微生物群转化液态猪粪为微生物肥料的新策略
Bihui Wang,Chunling Chang,Zhigang Wang et al.
Bihui Wang et al.
The pig industry generates copious amounts of liquid pig manure (LPM), which poses a great challenge to the environment; conventional treatment of the manure is often time-consuming and inefficient. We developed a novel technique for conver...
Coordinated synthesis of aromatic amino acid derived pigments in yeast via global transcriptional engineering [0.03%]
全局转录工程协调酵母中芳香族氨基酸来源色素的合成
Huimin Xue,Mingshan Li,Yuhui Cui et al.
Huimin Xue et al.
Background: Rational metabolic pathway engineering is capable of boosting upstream flux towards downstream synthesis of target products, such as aromatic amino acid derivatives. However, coordinated synthesis of multiple ...
Optimization of the fermentation process for fructosyltransferase production by Aspergillus niger FS054 [0.03%]
通过产酶菌株FS054发酵生产果糖基转移酶的优化研究
Yingzi Wu,Yuewen Zhang,Xiaoyu Zhong et al.
Yingzi Wu et al.
This study systematically optimized the fermentation process for fructosyltransferase (FTase) production by Aspergillus niger FS054, integrating traditional experimental designs with machine learning approaches. Single-factor experiments in...
Enhanced production of extracellular L-asparaginase in batch culture via nitrous acid-induced mutagenesis of Aspergillus oryzae [0.03%]
通过亚硝酸诱导法对米曲霉进行诱变以提高其批次培养中L-天冬酰胺酶的胞外产量
Sikander Ali,Sana Maqsood,Muhammad Usman Ahmad et al.
Sikander Ali et al.
Background: L-Asparaginase (LA) is an important enzyme with therapeutic and industrial applications, particularly in the treatment of leukemia. Enhancing its production through optimization and strain improvement is cruci...
Submicron infrared spectroscopy assessment of single-cell phenotypic diversity in microbial lipid production [0.03%]
亚微米红外光谱评估微生物脂质产生的单细胞表型多样性
Uladzislau Blazhko,Dana Byrtusová,Volha Shapaval et al.
Uladzislau Blazhko et al.
Background: Microbial lipid production offers a sustainable method for creating biofuels, lubricants, and high-value oils, utilizing the metabolic uniqueness of diverse organisms like bacteria, yeasts, and microalgae. How...
Engineering Pichia pastoris for the efficient production of the high-value steroid intermediate 15α-OH-D-ethylgonendione [0.03%]
改造毕赤酵母高效生产高附加值甾体中间体15α-OH-D-乙基固雄烯酮
Yu-Long Zeng,Yang-Yang Li,Bei-Feng-Chu Zheng et al.
Yu-Long Zeng et al.
15α-OH-D-ethylgonendione (15α-OH-DE) is a key intermediate for the synthesis of steroid drug gestodene, a major component of a new generation of powerful contraceptives. Synthetic access to 15α-OH-DE by chemical means is limited by low t...
Multiple factors based adaptive laboratory evolution strategy enhances DHA production in Aurantiochytrium sp. PKU#Mn16 by rewiring key metabolic pathways [0.03%]
基于多因素的适应性实验室进化策略通过重构关键代谢途径增强澳海藻菌PKU#Mn16DHA产量
Xueyan Ding,Xingyu Zhu,Yuetong Zhao et al.
Xueyan Ding et al.
Background: Marine protists Aurantiochytrium are recognized as promising sources for commercial lipid production, particularly due to their ability to produce high-value natural compounds like docosahexaenoic acid (DHA). ...
Review of research progress in immobilization and chemical modification of microbial enzymes and their application [0.03%]
微生物酶的固定化及化学修饰研究进展及其应用探讨
Walaa A Abdel Wahab
Walaa A Abdel Wahab
Enzyme stabilization is one of the most critical steps help in applying the enzymes on industrial scale efficiently. Enzymes have use in a variety of areas, including medical, industry, food, and even beauty and cosmetics. The industrial ap...
Biogenic Zinc nanoparticles: green approach to synthesis, characterization, and antimicrobial applications [0.03%]
生物锌纳米颗粒：合成、表征及抗菌应用的绿色方法
Myada S M Ouf,Mahmoud E A Duab,Dina I Abdel-Meguid et al.
Myada S M Ouf et al.
Background: Biogenic synthesis of zinc nanoparticles (ZnNPs) has attracted significant interest due to their unique properties and potential biological applications. Unlike chemical and physical methods, biogenic synthesi...