Molecular and biological characterization of pyocyanin from clinical and environmental Pseudomonas aeruginosa [0.03%]
临床及环境绿脓杆菌中嗜炎黄素的分子和生物学特性分析
Heba Shouman,Heba Shehta Said,Hany I Kenawy et al.
Heba Shouman et al.
Background: Pyocyanin is a secondary metabolite secreted by P. aeruginosa. It is a redox-active blue/green phenazine pigment that has various beneficial applications. The present study aims at screening the production of ...
Metabolic engineering strategies for naringenin production enhancement in Streptomyces albidoflavus J1074 [0.03%]
用于提高链霉菌J1074中柚皮素产生的代谢工程策略
Suhui Ye,Patricia Magadán-Corpas,Álvaro Pérez-Valero et al.
Suhui Ye et al.
Background: Naringenin is an industrially relevant compound due to its multiple pharmaceutical properties as well as its central role in flavonoid biosynthesis. ...
Mechanism of microbial production of acetoin and 2,3-butanediol optical isomers and substrate specificity of butanediol dehydrogenase [0.03%]
微生物生产丙酮酸和丁二醇对映体的机制及丁二醇脱氢酶的底物特异性
Yuchen Li,Xiangying Zhao,Mingjing Yao et al.
Yuchen Li et al.
3-Hydroxybutanone (Acetoin, AC) and 2,3-butanediol (BD) are two essential four-carbon platform compounds with numerous pharmaceutical and chemical synthesis applications. AC and BD have two and three stereoisomers, respectively, while the a...
A 4-hydroxybenzoate 3-hydroxylase mutant enables 4-amino-3-hydroxybenzoic acid production from glucose in Corynebacterium glutamicum [0.03%]
谷氨酸棒杆菌中的一种4-羟基苯甲酸3-羟基酶突变株使葡萄糖生产4-氨基-3-羟基苯甲酸成为可能
Kyoshiro Nonaka,Tatsuya Osamura,Fumikazu Takahashi
Kyoshiro Nonaka
Background: Microbial production of aromatic chemicals is an attractive method for obtaining high-performance materials from biomass resources. A non-proteinogenic amino acid, 4-amino-3-hydroxybenzoic acid (4,3-AHBA), is ...
Antibacterial peptide PMAP-37(F34-R), expressed in Pichia pastoris, is effective against pathogenic bacteria and preserves plums [0.03%]
毕赤酵母表达的抗菌肽PMAP-37(F34-R)对病原菌具有抑制作用并可用于山竹保鲜
Chunming Dong,Lijun Xu,Weitao Lu et al.
Chunming Dong et al.
Background: Recently, researchers have focused on the search for alternatives to conventional antibiotics. Antimicrobial peptides are small bioactive peptides that regulate immune activation and have antibacterial activit...
Co-utilization of glucose and xylose for the production of poly-β-hydroxybutyrate (PHB) by Sphingomonas sanxanigenens NX02 [0.03%]
Sphingomonas sanxanigenens NX02菌株协同利用葡萄糖和木糖生产聚3-羟基丁酸酯(PHB)
Yue Ming,Guoqiang Li,Zhuangzhuang Shi et al.
Yue Ming et al.
Background: Poly-β-hydroxybutyrate (PHB), produced by a variety of microbial organisms, is a good substitute for petrochemically derived plastics due to its excellent properties such as biocompatibility and biodegradabil...
Tuning transcription factor DegU for developing extracellular protease overproducer in Bacillus pumilus [0.03%]
调制转录因子DegU以提高枯草芽孢杆菌中胞外蛋白酶的产量
Chao-Ying Xie,Wen-Jin Li,Hong Feng
Chao-Ying Xie
Background: Global transcription machinery engineering (gTME) is an effective approach employed in strain engineering to rewire gene expression and reshape cellular metabolic fluxes at the transcriptional level. ...
Insight into de-regulation of amino acid feedback inhibition: a focus on structure analysis method [0.03%]
氨基酸反馈抑制去调控的见解——以结构分析方法为重点
Sadia Naz,Pi Liu,Umar Farooq et al.
Sadia Naz et al.
Regulation of amino acid's biosynthetic pathway is of significant importance to maintain homeostasis and cell functions. Amino acids regulate their biosynthetic pathway by end-product feedback inhibition of enzymes catalyzing committed step...
Expanding the genetic toolbox of Rhodotorula toruloides by identification and validation of six novel promoters induced or repressed under nitrogen starvation [0.03%]
通过鉴定和验证六个新型启动子扩展Rhodotorula toruloides遗传工具箱（这些启动子在氮饥饿条件下诱导或抑制）
Daniel P Brink,Friederike Mierke,Joakim Norbeck et al.
Daniel P Brink et al.
Background: The non-conventional yeast Rhodotorula toruloides is an emerging host organism in biotechnology by merit of its natural capacity to accumulate high levels of carotenoids and intracellular storage lipids from a...
The flavohaemoprotein hmp maintains redox homeostasis in response to reactive oxygen and nitrogen species in Corynebacterium glutamicum [0.03%]
解淀粉芽孢杆菌中的血红素蛋白Hmp响应活性氧和活性氮保护细胞氧化还原平衡
Ziqin Jiang,Jingyi Guan,Tingting Liu et al.
Ziqin Jiang et al.
Background: During the production of L-arginine through high dissolved oxygen and nitrogen supply fermentation, the industrial workhorse Corynebacterium glutamicum is exposed to oxidative stress. This generates reactive o...