Production of triacetic acid lactone from oleic acid by engineering the yeast Candida viswanathii [0.03%]
通过改造产酒粗糙酵母生产油酸来源的三醋酸内酯
Saptarshi Ghosh,Alex Hutagalung,Yuqian Gao et al.
Saptarshi Ghosh et al.
Triacetic acid lactone (TAL) is a promising platform chemical to produce valuable compounds. The development of engineered microbial hosts to efficiently produce TAL from lipid-containing waste streams could be a cost-effective, sustainable...
Enhanced myco-synthesis of selenium and zinc oxide nanoparticles and evaluating their anticancer activities and role against antibiotic resistance genes in certain bacterial strains [0.03%]
一种增强的真菌合成硒和氧化锌纳米颗粒的方法及其抗肿瘤活性和对抗某些细菌菌株的抗生素耐药基因的作用评价
Amira Mohamed,El-Sayed R El-Sayed,Zainab Zakaria et al.
Amira Mohamed et al.
Background: In an array to check microbial resistance against generally used antibiotics, it is essential to create innovative and efficient antimicrobial agents. Therefore, nanoparticles (NPs) with their antimicrobial ac...
Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling [0.03%]
通过稳定同位素标记扩大真菌苝醌的生产规模并研究其生物合成路径
Reema A Al-Qiam,Sachin Dumbare,Tyler N Graf et al.
Reema A Al-Qiam et al.
Background: Perylenequinones, such as hypocrellins and hypomycins, are fungal secondary metabolites with potential for pharmaceutical and industrial applications due to both their physical and biological properties. This ...
Biosynthesis of tauro-ursodeoxycholic acid (TUDCA) in Saccharomyces cerevisiae [0.03%]
在酿酒酵母中合成牛磺鹅脱氧胆酸(TUDCA)
Seonyun Moon,Michael J Smanski
Seonyun Moon
Tauroursodeoxycholic acid (TUDCA) is a microbial bile acid known for its diverse yet still largely unexplored biological activities. Traditionally used in Asian medicine, TUDCA and the taurine-free form, ursodeoxycholic acid (UDCA), share s...
Biosynthesis of tauro-ursodeoxycholic acid (TUDCA) in Saccharomyces cerevisiae [0.03%]
在酿酒酵母中合成牛磺鹅去氧胆酸(TUDCA)
Seonyun Moon,Michael J Smanski
Seonyun Moon
Tauroursodeoxycholic acid (TUDCA) is a microbial bile acid known for its diverse yet still largely unexplored biological activities. Traditionally used in Asian medicine, TUDCA and the taurine-free form, ursodeoxycholic acid (UDCA), share s...
Effect of different colloidal gold nanomaterials on Ganoderma lingzhi fermentation for production of ganoderma polysaccharide and triterpenoid through macroscopic and microscopic investigation [0.03%]
不同胶体金纳米材料对灵芝发酵生产多糖和三萜的影响及宏观和微观研究
Mengqiu Luo,Muling Shi,Yang Li et al.
Mengqiu Luo et al.
Ganoderma lingzhi (G. lingzhi) is a Basidiomycete macrofungus valued for its secondary metabolites with pharmacological activity. To enhance the biosynthesis of secondary metabolites, various exogenous additives have been introduced to fung...
Unlocking efficient polyhydroxyalkanoate production by Gram-positive Priestia megaterium using waste-derived feedstocks [0.03%]
利用废料基质解锁产聚羟基烷酸细菌的高效生产性能
Xinyi Bai,Libo Xu,Kang Li et al.
Xinyi Bai et al.
Polyhydroxyalkanoates (PHA) are sustainable alternatives to conventional plastics due to biodegradability and biocompatibility. However, most PHA-producing strains are Gram-negative, which co-produce endotoxins that limit their applicabilit...
Engineering the oleaginous yeast Yarrowia lipolytica for co-production of phenolic monoterpenes thymol and carvacrol [0.03%]
工程技术黄青酵母雅罗弱拟酵母共生产酚类单萜素伏烯和香荆芹酚
Junkai Zhu,Yi Zhang,Haibo Jiang et al.
Junkai Zhu et al.
Background: Thymol and carvacrol are natural phenolic compounds with various biological activities. They are widely used in the spice and medicine industries. Production of thymol and carvacrol using microbial cell factor...
Heidi Tuomela,Johanna Koivisto,Elena Efimova et al.
Heidi Tuomela et al.
Background: Lignin holds great potential as an abundant and sustainable source of aromatic compounds, offering a viable alternative to fossil-based resources for producing chemicals and materials. Biological upgrading of ...
Bacteria-based immunosuppressive tumor microenvironment reprogramming: a promising dawn in cancer therapy [0.03%]
基于细菌的免疫抑制性肿瘤微环境重编程：癌症治疗的新希望
Mostafa Akbariqomi,Peyman Kheirandish Zarandi,Azam Abedi et al.
Mostafa Akbariqomi et al.
Traditional chemotherapy, a prevalent cancer treatment modality, is associated with significant side effects and often leads to treatment failure. Non-specific drug distribution and chemoresistance are the main factors contributing to this ...