Advances in biomanufacturing and recent biological applications of the fundamental bacterial carotenoids: a comprehensive review [0.03%]
生物制造的最新进展及细菌类胡萝卜素在生物学应用中的作用：综合述评
Khaled B Al-Monofy,Mahmoud H Farghali,Lamiaa A Al-Madboly et al.
Khaled B Al-Monofy et al.
Many research teams have prioritized the investigation of the biotechnological production of carotenoids in the last few decades due to their multipurpose application. In this review, the bioproduction of the fundamental bacterial carotenoi...
Aokap9 gene knockout contributes to kojic acid synthesis in Aspergillus oryzae [0.03%]
曲霉aokap9基因敲除参与抑制马来素合成
Ting Qiu,Huanxin Zhang,Yuzhen Li et al.
Ting Qiu et al.
Background: Kojic acid, a significant secondary metabolite primarily synthesized by Aspergillus oryzae, has extensive applications across various industries. It is imperative to identify effective gene targets that can en...
Identification and characterization of a novel β-galactosidase active at low temperatures from the Antarctic fungus Tetracladium sp., expressed in Saccharomyces cerevisiae [0.03%]
一种来自南极霉菌Tetracladium的新型耐冷β-半乳糖苷酶的鉴定及性质表征，并在酵母中表达该酶
Fernando Gutierrez,Jennifer Alcaino,Victor Cifuentes et al.
Fernando Gutierrez et al.
Background: β-Galactosidases are widely used in the dairy industry to produce lactose-free milk and prebiotics such as galacto-oligosaccharides and lactulose. Since commercial β-galactosidases have optimal activity at 3...
Stress response regulation to extracellular polymeric substances biosynthesis in Bacillus licheniformis [0.03%]
枯草芽孢杆菌通过应激反应调控胞外多糖的合成
Xiaoyu Wei,Ziwei Pan,Zhen Chen et al.
Xiaoyu Wei et al.
Background: The diverse metabolic mechanisms underlying bacterial extracellular polymeric substances give rise to a wide array of components with distinct functionalities, including exopolysaccharides (EPS) and poly-γ-gl...
Uncoupling protein production from growth: different strategies for intracellular and secreted proteins in yeast [0.03%]
解耦蛋白质生产与生长：酵母细胞内蛋白和分泌型蛋白的不同策略
Nuran Temelli,Willem H Baris,Ruud A Weusthuis et al.
Nuran Temelli et al.
Background: Precision fermentation offers a sustainable alternative production route for proteins but still suffers from moderate productivities and low yields. Especially compared to biomass yields, recombinant protein y...
Solution towards low yield biosurfactant production from bacteria, a novel approach using microalgae-bacteria consortium [0.03%]
利用微藻-细菌菌落解决生物表面活性剂产量低的问题的一种新方法研究
Yan Jer Ng,Kuan Shiong Khoo,Kit Wayne Chew et al.
Yan Jer Ng et al.
Background: Surfactants are an important chemical in the industry due to their unique properties to reduce surface tension between fluids. To date, raw materials involved for the synthesis of surfactants are mostly derive...
Overexpression of Scr1 protein induces strong changes in the transcriptome and metabolome of Streptomyces coelicolor that affect antibiotic production [0.03%]
Scr1蛋白过表达引起放线菌素灰链霉菌转录组和代谢组显著改变并影响抗生素生成
Carolina Riascos,Gemma Fernández-García,Javier García-Martín et al.
Carolina Riascos et al.
Background: Xenobiotic response element (XRE) regulator proteins play an important role in gene regulation in Streptomyces. In these bacteria, they are often encoded together with a small protein containing a DUF397 domai...
Development and clinical application of a PCR-UV assay for detection of carbapenem resistant Acinetobacter baumannii in bloodstream infections [0.03%]
多重PCR联合紫外分光光度法检测血流感染中碳青霉烯耐药鲍曼不动杆菌及其临床应用
Lin Yu,Jingzhi Zhang,Ze Liu et al.
Lin Yu et al.
Objective: Bloodstream infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) are a significant public health problem, with high morbidity and mortality. Detection and identification of CRAB is essential...
Effects of bioreactor inoculation method on secondary metabolite production and morphological characteristics of Streptomyces rimosus in microparticle-enhanced cultivation (MPEC) [0.03%]
生物反应器接种方法对Microparticle-Enhanced Cultivation（MPEC）中链霉菌里摩素亚种次级代谢产物及形态特征的影响
Anna Ścigaczewska,Tomasz Boruta,Marcin Bizukojć
Anna Ścigaczewska
Streptomyces rimosus is renowned for complex metabolic pathways and the ability to produce diverse bioactive secondary metabolites, including antibiotics, antifungals, and other biologically active compounds. Despite their industrial signif...
Functional characterization of lactate metabolism and its key regulatory genes reveals lactate-mediated modulation of carbon and nitrogen metabolism in Phaeodactylum tricornutum [0.03%]
乳酸代谢及其关键调控基因的功能表征揭示了乳酸对三角褐指藻碳和氮代谢的调节作用
Jiawen Duan,Yi Zhang,Chenhui Li et al.
Jiawen Duan et al.
Background: The marine diatom Phaeodactylum tricornutum plays a crucial role in global carbon and nitrogen cycling. Previous work revealed that lactate regulates carbon and nitrogen metabolism of P. tricornutum through pr...