Cell-free synthesis and characterization of Salmonella, Escherichia coli, and Shigella-specific bacteriophages [0.03%]
无细胞合成并表征沙门氏菌、大肠杆菌和志贺氏菌噬菌体
Irem Iskender,Jaap Bosma,Paul Soudier et al.
Irem Iskender et al.
Background: Cell-free gene expression (CFE) systems provide a rapid and modular platform for synthesizing bacteriophages without the need for living host cells. However, the generalizability of CFE-based phage synthesis a...
Correction: Bacillus thuringiensis as a factory producing parasporin toxins with promising anticancer properties: a review [0.03%]
关于芽孢杆菌寄生素作为具有抗癌性质的毒素生产车间的综述的更正通知
Natalia Musiuk,Wioleta Lewandowska,Aleksandra Rembiszewska et al.
Natalia Musiuk et al.
Published Erratum
Microbial cell factories. 2026 Jun 24;25(1):146. DOI:10.1186/s12934-026-03046-2 2026
Multi-omics-guided metabolic engineering of Limosilactobacillus reuteri for high-level 3-hydroxypropionaldehyde production from glucose [0.03%]
基于多组学指导的葡萄糖高产3-羟基丙醛工程解脂拉克替肠菌合成路线研究
Zuojun Liu,Qiang Yin,Liang Li et al.
Zuojun Liu et al.
Background: Limosilactobacillus reuteri is an important probiotic chassis for producing 3-hydroxypropionaldehyde (3-HPA), a broad-spectrum antimicrobial and biochemical. However, its production is constrained by a metabol...
Exploring the metabolic burden of surfactin biosynthesis and the metabolic costs of srfA operon expression in Bacillus subtilis [0.03%]
枯草芽孢杆菌表面活性素生物合成的代谢负担及其srfA操纵子表达的代谢消耗的研究
Elvio Henrique Benatto Perino,Eric Hiller,Maliheh Vahidinasab et al.
Elvio Henrique Benatto Perino et al.
The biosynthesis of surfactin, a potent lipopeptide biosurfactant produced by Bacillus subtilis, imposes a significant metabolic burden on the host organism. Understanding the metabolic costs associated with surfactin production, specifical...
Biological production of muconic acid from renewable biomass: advances in metabolic engineering and lignin valorisation [0.03%]
利用可再生生物量生物合成木醋酸的研究进展：代谢工程和木质素高值化方面的成就
Vinod Kumar,Satish Kumar Ainala,Vivek Kumar Gaur et al.
Vinod Kumar et al.
Muconic acid (MA) is characterized by two reactive carboxylic acid groups and two conjugated double bonds, making it a highly valuable industrial platform chemical with significant market potential. It serves as a key intermediate in the ma...
Identification and characterization of a novel leaderless bacteriocin toyoncin T35 from Bacillus toyonensis [0.03%]
来源于枯草芽孢杆菌的新颖无信号肽细菌素toyoncin T35的鉴定和表征
Xiaofeng Zhang,Haihua Wang,Chenxu He et al.
Xiaofeng Zhang et al.
Background: Antibiotics residues and antibiotics resistance have become a serious threat to human health. There is an urgent need for the development of antibiotic alternatives. Bacteriocins are considered one of the alte...
Metabolomic insights into functional protein mediated salt stress adaptation in the osmophilic yeast Zygosaccharomyces rouxii [0.03%]
盐胁迫下高渗酵母Zygosaccharomyces rouxii适应的代谢组学见解
Dingkang Wang,Lerong Liu,Sha Liu et al.
Dingkang Wang et al.
Background: High salinity inhibits microbial growth by disturbing osmotic balance, redox equilibrium, and membrane integrity. Zygosaccharomyces rouxii, an osmophilic yeast widely used in high-salt fermented foods, has evo...
Engineering Komagataella phaffii for secreted and surface-displayed production of SARS-CoV-2 receptor-binding domain and its immunogenicity evaluation [0.03%]
基因工程改造毕赤酵母分泌和细胞表面展示SARS-CoV-2刺突蛋白受体结合域及其免疫学特性分析
Kostyantyn Dmytruk,Olena Dmytruk,Marta Semkiv et al.
Kostyantyn Dmytruk et al.
Background: The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein represents a key antigen for vaccine development due to its critical role in the ACE2 receptor recognition. Yeast-based expression systems, par...
Novel utilization of the seaweed-based deoxy sugars rhamnose and fucose by engineered Corynebacterium glutamicum [0.03%]
工程改造棒状杆菌谷氨酸菌株利用海藻来源的去氧糖鼠李糖和半乳糖醛酸的新方法
Ida Marie Stephansen,Luciana Fernandes Brito,Oliver Saur Auran et al.
Ida Marie Stephansen et al.
Seaweed represents a potential sustainable carbon source for industrial biotechnology, yet the workhorse bacterium Corynebacterium glutamicum cannot naturally metabolize the deoxy sugars L-rhamnose and L-fucose, abundant in green and brown ...
Development of a novel hydroxylated recombinant human type III collagen TD-1-HrHC in Komagataella phaffii with transdermal and skin damage repair activity [0.03%]
一种新型羟基重组人III型胶原蛋白TD-1-HrHC的开发及其透皮性和皮肤损伤修复作用研究
Yangyang Li,Yehai Wang,Jingjing Yue et al.
Yangyang Li et al.
Background: Collagen has been proven to have significant potential applications value in the fields of on medical aesthetics and cosmetics. However, due to its large molecular weight, collagen is difficult to effectively ...