Multi-layered engineering of Aspergillus terreus enhances biosynthesis of the plant-derived fungicide physcion [0.03%]
多层策略改造地曲霉菌高效生产植物来源杀菌剂仙鹤通酸_physcion
Zilin Ren,Yingying Xue,Ning Xu et al.
Zilin Ren et al.
Background: Emodin and its derivatives are important bioactive anthraquinones from rhubarb, with diverse pharmacological activities. Physcion, an O-methylated derivative of emodin, is a promising plant-derived fungicide a...
Characterization and bioactivities of glutaminase-free L-asparaginase from Salinicola acorporae S4-41 [0.03%]
来自盐单胞菌(Salinicola acorporae)S4-41的无谷氨酰胺酶L-天冬酰胺酶的性质及生物活性
Abd El Raheem El-Shanshoury,Hadeer Helmy Abosamra,Tamer Elsakhawy
Abd El Raheem El-Shanshoury
Background: The medical community has long searched for a safer and more effective cancer treatment method. Clinically, L-asparaginase derived from bacteria has shown promising results. However, it carries the risk of imm...
Effect of hydrogen peroxide and carbon-to-nitrogen ratio on growth and biochemical profile in oleaginous mucoromycota [0.03%]
过氧化氢和碳氮比对产油虫卵壶菌门生长及生化特征的影响
Cristian Bolaño-Losada,Boris Zimmermann,Svein Jarle Horn et al.
Cristian Bolaño-Losada et al.
Background: Hydrogen peroxide (H2O2) has gained attention as cofactor of lytic polysaccharide monooxygenases (LPMOs) during lignocellulose saccharification. The action of these enzymes has been shown to significantly enha...
Ethanol induced oxidative stress, mitochondrial dysfunction, and autophagy in Wickerhamomyces anomalus [0.03%]
异常威克汉霉菌中的乙醇诱导的氧化应激、线粒体功能障碍和自噬
Xiaozhu Liu,Yujie Wang,Hongyue Xu et al.
Xiaozhu Liu et al.
Wickerhamomyces anomalus, a flavor-modulating non-Saccharomyces yeast used in winemaking, experiences escalating ethanol stress during fermentation, yet the physiological and structural consequences remain unclear. This study assessed respo...
Bacillus subtilis as cell factory for enhanced production of the biopolymer precursor pyridine-2,6-dicarboxylic acid [0.03%]
用枯草芽孢杆菌生产生物聚合物前体吡啶-2,6-二甲酸
Taichi Chen,Haris Uzunovic,Stanley Brul et al.
Taichi Chen et al.
Background: Pyridine-2,6-dicarboxylic acid (DPA) is a valuable dicarboxylic acid that has the potential to serve as a precursor for bio-sustainable and bio-degradable materials and self-healing polymers. It also plays a c...
Production of hydrogen from crude glycerol via an integrated process of L-malate biosynthesis by Escherichia coli and photofermentation by Rhodobacter capsulatus [0.03%]
大肠杆菌L-苹果酸生物合成与紫色光养细菌光发酵联产氢气及其原料粗甘油的应用研究
Jose L Marcos,Gema Cabrera,Daniel F Hernandez et al.
Jose L Marcos et al.
Biorefinery is an innovative concept for resource utilization. To further increase its efficiency, the integration of different biomass conversion technologies (integrated biorefinery) is essential. Biodiesel, a traditional biofuel, generat...
Optimising Chlorella vulgaris bioflocculation by Aspergillus Niger pellets and their application in wastewater treatment and lipid production [0.03%]
用于废水处理和脂质生产的曲霉菌颗粒优化小球藻生物絮凝性能
Abeer Mohamed,Eman Owis,Gamal Abdel-Fattah et al.
Abeer Mohamed et al.
Background: Co-culturing filamentous fungi with microalgae is thought to be a viable method for effective microalgae bioflocculation. Using filamentous fungus makes it possible to produce big, flocculated pellets without ...
Next-generation stress-inducible Komagataella phaffii promoter variants [0.03%]
下一代应激诱导的Komagataella phaffii启动子变异体
Katharina Ebner,Núria Bernat-Camps,Simona Scheipel et al.
Katharina Ebner et al.
Background: Expanding the promoter toolbox of Komagataella phaffii (K. phaffii) in terms of strength and regulatory flexibility can significantly enhance bioprocess efficiency for recombinant protein and metabolite produc...
Metabolic engineering of Streptomyces explomaris for increased production of the reverse antibiotic nybomycin [0.03%]
芽孢链霉菌的代谢工程以提高其产生反式抗生素nybomycin的产量
Wei Shu,Julian Stegmüller,Marta Rodriguez-Estevez et al.
Wei Shu et al.
Background: Nybomycin is a reverse antibiotic with selective activity against fluoroquinolone-resistant Gram-positive bacteria, including Staphylococcus aureus, making it a promising candidate to fight against antimicrobi...
Characterization of the unconventional meroterpenoid gene cluster from Stachybotrys sp. CPCC 401591 for phenylspirodrimanes biosynthesis [0.03%]
链格孢属菌株CPCC 401591中苯 Spirodrimanoids生物合成非典型次级代谢基因簇的表征
Hui Lv,Bailin Song,Lingjin Bu et al.
Hui Lv et al.
Background: Phenylspirodrimanes (PSDs) are a unique class of meroterpenoids that have been extensively studied due to their diverse biological activities. These metabolites are supposedly biosynthesized through the farnes...