Aggregation-controlled photophysics of m-THPP: restoring singlet oxygen generation via albumin and pluronic carriers [0.03%]
m-THPP的聚集调控光物理性质：通过白蛋白和PLURONIC载体恢复单线态氧生成能力
Aleksander Kolman,Anna Lewandowska-Andralojc
Aleksander Kolman
The photophysical properties of meso-tetra(hydroxyphenyl)porphyrin (m-THPP) were investigated to elucidate how aggregation in aqueous media affects its ground- and excited-state behavior and to identify carrier systems capable of preserving...
Beyond photobleaching: radical-driven photocleavage and destaining mechanisms in chromophore-biomolecule conjugates [0.03%]
超越光漂白：染料-生物大分子缀合物中自由基驱动的光裂解和去色机制
Victor Akpe,Ian E Cock
Victor Akpe
Chromophore-biomolecule conjugates have evolved far beyond their origins as passive fluorescent labels, emerging as mechanistically rich photochemical systems capable of reporting, modulating, and disrupting biological structures with molec...
Design and characterization of a photoactivatable manganese-porphyrin based nanozyme for biomedical and environmental applications [0.03%]
一种用于生物医学和环境应用的光激活锰卟啉纳米酶的开发与表征
M Agostina Biondi,Matías Rabasa,Julieta M Parisi et al.
M Agostina Biondi et al.
Nanozymes have emerged as versatile, enzyme-mimicking nanomaterials with broad applications in catalysis, biology, and medicine. In this work, we report the design and characterization of a novel photoactivatable nanozyme constructed from s...
Synthesis and photophysical properties of quaternaphthalenes: topology-dependent radiative dynamics in deep-blue emitters [0.03%]
萘类分子的拓扑结构对其深蓝色发光性质的影响研究
Minoru Yamaji,Kengo Suzuki,Hideki Okamoto
Minoru Yamaji
A series of quaternaphthalenes (QNps) containing four naphthalene chromophores were synthesized and investigated as all-hydrocarbon multi-chromophore emitters. The QNps exhibited near-UV to deep-blue fluorescence in solution and retained em...
A dicyanoisophorone-based fluorescent probe for highly selective recognition of F⁻ [0.03%]
一种高选择性识别F⁻离子的二氰基异香豆素类荧光探针
Ruonan Xie,Weiguang Zhao,Guihui Li et al.
Ruonan Xie et al.
In this study, a novel pyrazole derivative DCI-1 was rationally designed and synthesized using dicyanoisophorone as the fluorophore. The optical properties and recognition performance of DCI-1 were systematically investigated. Experimental ...
Amélie Aubert,Antoine Fayeulle,Muriel Vayssade et al.
Amélie Aubert et al.
Antibiotics can be released into the environment when used to treat bacterial infections in humans and animals. These residues are poorly removed by wastewater treatment processes, leading to the selection of bacterial antibiotic resistance...
Doubly protected ester prodrug of 5-aminolevulinic acid for enhanced cell uptake and photoinactivation [0.03%]
一种5-氨基乙酰丙酸双保护酯前药，用于增强细胞摄取和光灭活作用
Hailey S Sanders,Karolina A Rooney,Marissa A Panethiere et al.
Hailey S Sanders et al.
Photodynamic therapy (PDT) employs a molecular photosensitizer combined with light to induce localized cellular toxicity. The natural product, 5-aminolevulinic acid (5-ALA), is used in clinical PDT as a precursor drug molecule that is conve...
Spin trap-mediated conversion of singlet oxygen to hydroxyl radical in photosensitization: mechanistic insights and the role of biological reductants [0.03%]
超氧转化为羟基自由基的自旋捕获机理研究及生物还原剂的作用机制
Chiho Nishizawa,Shoko Okazaki,Keizo Takeshita et al.
Chiho Nishizawa et al.
For medical applications of photosensitization, it is crucial to identify the reactive species generated. Previous studies have shown that during photosensitization, the nitrone spin trap 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) converts sin...
Exploring the structural, morphological and optical properties of iron based metalloporphyrin in the nano regime for biomedical applications [0.03%]
基于铁的金属卟啉在纳米尺度下的结构性质、形貌性质和光学性质在生物医学中的应用研究
Anaswara Biju Mini,Nidhi Madhukumaran Nair,Arun Unnikrishna Pillai et al.
Anaswara Biju Mini et al.
Iron-Based metalloporphyrin Fe-TCPP (iron (III) tetra(4-carboxyphenyl) porphyrin) is a promising photosensitizer utilized in photodynamic therapy (PDT). In this work, the structural, morphological, optical, and cell viability characteristic...
Emission-tunable aromatic thiadiazole derivatives based on triphenylimidazole with aggregation-induced emission activity and their application in osteosarcoma imaging [0.03%]
基于三苯基咪唑的发射可调芳香硫杂稠环衍生物的聚集致发光及其在骨肉瘤成像中的应用研究
Chen Zhang,Jun Wang
Chen Zhang
Aggregation-induced emission (AIE)-active fluorescent probes have emerged as promising tools for in vivo biomarker detection and biological imaging due to their unconventional emission behavior in aggregated state. In this study, we designe...