Nethusan Sivanesan,Gabriela M Diaz,Preston C Sprenkle
Nethusan Sivanesan
Purpose of review: This review presents the latest research in tissue-based genomic testing in localized prostate cancer (PCa). Here we explore the current and most commonly used genomic assays, their clinical application...
Biochemical recurrence after radical prostatectomy and postoperative radiotherapy: current evidence and controversial issues [0.03%]
根治性前列腺切除术后生化复发后的放疗:当前证据及争议问题
Mattia Longoni,Fabian Falkenbach,Markus Graefen et al.
Mattia Longoni et al.
Purpose of review: This review explores challenges in managing biochemical recurrence (BCR) after radical prostatectomy and postoperative radiotherapy for prostate cancer (PCa) highlighting gaps in risk stratification, im...
Cost-effectiveness of serum, urine, and tissue-based prostate cancer biomarkers [0.03%]
基于血液、尿液和组织的前列腺癌生物标志物的成本效益分析
Veerain K Gupta,Brian D Cortese,Ruchika Talwar
Veerain K Gupta
Purpose of review: Prostate cancer remains a leading malignancy among men in the United States. While prostate-specific antigen (PSA) screening improves early detection, it also leads to over-diagnosis and over-treatment....
Emerging strategies: conservative management of upper tract urothelial carcinoma [0.03%]
新兴策略:上尿路尿路上皮癌的保守治疗
Orel Hemo,Tomer Hasdai,Hen Hendel et al.
Orel Hemo et al.
Purpose of review: Upper tract urothelial carcinoma (UTUC) is a rare yet aggressive malignancy, representing 5-10% of urothelial cancers. While radical nephroureterectomy (RNU) has traditionally offered excellent oncologi...
Paolo Zaurito,Armando Stabile,Francesco Montorsi et al.
Paolo Zaurito et al.
Purpose of review: Multiparametric MRI (mpMRI) has been included in the diagnostic pathway of prostate cancer (PCa). However, the role of this imaging modality in predicting clinical outcomes after diagnosis has been poor...
Prostate-specific membrane antigen positron-emission tomography for novel risk-stratification of biochemical recurrence [0.03%]
前列腺特异性膜抗原正电子发射断层扫描用于生化复发危险分层
Madeleine J Karpinski,Claudia Kesch,Boris A Hadaschik et al.
Madeleine J Karpinski et al.
Purpose of review: The variety of prostate cancer aggressiveness in patients with biochemical recurrence (BCR) leads to the unmet need of accurate risk stratification. This review examined the recently published risk stra...
Salvage treatment of local recurrence following radical and partial nephrectomy [0.03%]
根治性肾切除术和部分肾切除术后再发的补救治疗
Davide Perri,Carlotta Palumbo,Alessandro Volpe
Davide Perri
Purpose of review: Standardized definition of local recurrence after radical or partial nephrectomy is still lacking. Due to its rarity, data on natural history, oncological outcomes and prognostic factors are scarce and ...
Christian Corsini,Edoardo Pozzi,Andrea Salonia
Christian Corsini
Purpose of review: The aim of this study was to outline the role of genetic abnormalities, including chromosomal anomalies, single-gene mutations, epigenetic changes, and mitochondrial DNA (mtDNA) defects, in male factor ...
Small tools, big impact and redefining endourology: the paradigm shift of ureteroscopy for large stones and percutaneous nephrolithotomy for small stones - a literature review [0.03%]
化繁为简,影响深远——再思输尿管软镜与经皮肾镜的适应证变迁:文献回顾
Maria Florencia Frascheri,Pablo Contreras,Dmitry Enikeev et al.
Maria Florencia Frascheri et al.
Purpose of review: We aim to review the evolving paradigm in endourology, where technology has led us to manage small stones with ureteroscopy (URS) and large stones with miniaturized percutaneous nephrolithotomy (mPCNL) ...