Autoimmune encephalitis with anti-leucine-rich glioma-inactivated 1 or anti-contactin-associated protein-like 2 antibodies (formerly called voltage-gated potassium channel-complex antibodies) [0.03%]
抗L-糖醇脱氢酶氧化酶/还原酶1或抗接触素关联蛋白样2抗体(先前称为电压门控钾通道复合物抗体)相关自身免疫性脑炎
Anna E M Bastiaansen,Agnes van Sonderen,Maarten J Titulaer
Anna E M Bastiaansen
Purpose of review: Twenty years since the discovery of voltage-gated potassium channel (VGKC)-related autoimmunity; it is currently known that the antibodies are not directed at the VGKC itself but to two closely associat...
Myelin oligodendrocyte glycoprotein antibodies: How clinically useful are they? [0.03%]
少突胶质细胞髓鞘寡突胶质细胞糖蛋白抗体的临床实用性如何?
Markus Reindl,Sven Jarius,Kevin Rostasy et al.
Markus Reindl et al.
Purpose of review: Serum IgG autoantibodies against the myelin oligodendrocyte glycoprotein (MOG) are present in atypical demyelinating disorders such as neuromyelitis optica spectrum disorders (NMOSD) or acute disseminat...
Co-occurrence of migraine and atopy in children and adolescents: myth or a casual relationship? [0.03%]
儿童和青少年偏头痛与特应性共病:迷思还是偶然关系?
Aynur Özge,Derya Uluduz,Hayrunnisa Bolay
Aynur Özge
Purpose of review: To clarify the causal relationship between migraine and atopic disorders in children and adolescents. Recent findings: ...
Rami Burstein,Pamela Blake,Aaron Schain et al.
Rami Burstein et al.
Purpose of review: To summarize recent clinical and preclinical studies on extracranial pathophysiologies in migraine. It challenges the opinion-based notion that the headache phase of migraine occurs without input from p...
Laura H Schulte,Arne May
Laura H Schulte
Purpose of review: One of the most discussed topics in migraine pathophysiology is where migraine attacks originate. Although recent evidence suggests central attack generating loci, there is an ongoing debate about the i...
Calcitonin gene-related peptide monoclonal antibodies for migraine prevention: comparisons across randomized controlled studies [0.03%]
针对偏头痛预防的 calcitonin 相关肽单克隆抗体:随机对照研究比较分析
Dimos D Mitsikostas,Uwe Reuter
Dimos D Mitsikostas
Purpose of review: The results of phase 2 randomized controlled trials for the prevention of episodic and chronic migraine demonstrating the efficacy and safety of four mAbs targeting the calcitonin gene-related peptide (...
Samaira Younis,Anders Hougaard,Mark B Vestergaard et al.
Samaira Younis et al.
Purpose of review: To present an updated and streamlined overview of the metabolic and biochemical aspect of the migraine pathophysiology based on findings from phosphorous (P) and hydrogen (H) magnetic resonance spectros...
Seizures and risk of epilepsy in autoimmune and other inflammatory encephalitis [0.03%]
自身免疫性及其他炎性脑病的癫痫发作与癫痫风险的关系
Marianna Spatola,Josep Dalmau
Marianna Spatola
Purpose of review: The aim of this study was to assess the seizure manifestations and risk of epilepsy in encephalitis associated with antibodies against neuronal cell-surface (autoimmune encephalitis) or myelin-associate...
Detecting synaptic autoantibodies in psychoses: need for more sensitive methods [0.03%]
精神疾病中突触自身抗体的检测:需要更敏感的方法
Joseph C Masdeu
Joseph C Masdeu
Purpose of review: Schizophrenic psychosis affects near 1% of the population. It typically starts in the first three decades of life, leading most often to chronic disability: antipsychotic treatment is palliative, not cu...
Postviral autoimmune encephalitis: manifestations in children and adults [0.03%]
病毒感染后的自身免疫性脑炎:儿童和成人患者的临床表现
Harald Prüss
Harald Prüss
Purpose of review: Autoimmune encephalitis is an increasingly recognized neuropsychiatric condition seen in patients of all ages. Herpes virus infections of the brain can antedate the development of pathogenic autoantibod...