Editorial: introducing the new Co-Editors-in-Chief of Current Opinion in Neurology [0.03%]
现任主编述评：神经病学观点新主编上任
David Eidelberg,Jean-Marc Léger
David Eidelberg
Widening the spectrum of inflammatory disorders of the central nervous system [0.03%]
扩大中枢神经系统炎症性疾病的谱系
Francesc Graus
Francesc Graus
David A Reardon,Patrick Y Wen,Kai W Wucherpfennig et al.
David A Reardon et al.
Purpose of review: Immunotherapy has emerged as a cornerstone of modern oncology with regulatory approvals for a variety of immunotherapeutics being achieved for a spectrum of cancer indications. Nonetheless the role of t...
Céline Louapre,Benedetta Bodini,Catherine Lubetzki et al.
Céline Louapre et al.
Purpose of review: Studies of large longitudinal cohorts of patients with multiple sclerosis (MS) have emphasized the prognostic value of conventional MRI markers, at least during early stages. Advanced imaging metrics de...
Alan J Thompson
Alan J Thompson
Purpose of review: Understanding the mechanisms underlying progression in multiple sclerosis (MS) and identifying appropriate therapeutic targets is a key challenge facing the MS community. This challenge has been champio...
Endothelial cells and lymphatics at the interface between the immune and central nervous systems: implications for multiple sclerosis [0.03%]
中枢神经系统和免疫系统交界处的内皮细胞和淋巴管：多发性硬化症的潜在治疗靶点
Céline Meyer,Guillaume Martin-Blondel,Roland S Liblau
Céline Meyer
Purpose of review: The central nervous system (CNS) has a unique relationship with the immune system. This review highlights the distinct roles of lymphatic vessels and endothelial cells in the interface between CNS and i...
Pediatric multiple sclerosis [0.03%]
儿童多发性硬化症
Anusha K Yeshokumar,Sona Narula,Brenda Banwell
Anusha K Yeshokumar
Purpose of review: This review discusses the epidemiologic factors involved in the pathogenesis of pediatric multiple sclerosis (MS), which have been the focus of numerous studies in the last several years. We also review...
Redefining progressive encephalomyelitis with rigidity and myoclonus after the discovery of antibodies to glycine receptors [0.03%]
抗甘氨酸受体抗体发现后波动性脑脊髓炎伴强直阵挛的重新定义
Sarah J Crisp,Bettina Balint,Angela Vincent
Sarah J Crisp
Purpose of review: This review highlights the recent discovery of antibodies to glycine receptor (GlyR-Ab) and discusses the relationship between these antibodies and neurological disorders. ...
Romain Marignier,Alvaro Cobo Calvo,Sandra Vukusic
Romain Marignier
Purpose of review: The discovery of highly specific auto-antibodies directed against the water channel aquaporin 4 was a quantum leap in the definition, classification and management of neuromyelitis optica (NMO). Herein,...
CNS syndromes associated with antibodies against metabotropic receptors [0.03%]
元神经肽受体自身抗体相关的中枢神经系统综合征
Eric Lancaster
Eric Lancaster
Purpose of review: Autoantibodies to Central nervous system (CNS) metabotropic receptors are associated with a growing family of autoimmune brain diseases, including encephalitis, basal ganglia encephalitis, Ophelia syndr...