Isocitrate dehydrogenase mutation and microenvironment in gliomas: do immunotherapy approaches matter? [0.03%]
异柠檬酸脱氢酶突变和胶质瘤微环境：免疫治疗策略重要吗？
Michael Platten
Michael Platten
Purpose of review: Gliomas with mutations in the gene for isocitrate dehydrogenase (IDH) display a unique immune microenvironment that is distinct from IDH-wildtype gliomas. This unique immune microenvironment is shaped b...
Albert Ludolph
Albert Ludolph
Roger Collet-Vidiella,Alberto De Lorenzo,Luis Querol
Roger Collet-Vidiella
Purpose of review: Autoimmune nodopathies (AN) are a recognized distinct group of immune-mediated peripheral neuropathies with unique immunopathological features and therapeutic implications. This review synthesizes recen...
Heterogeneity of frequencies of motor neuron disease across ethnicities and geographical areas: focus on Arabic countries in the Mediterranean area [0.03%]
地中海区域不同民族和地理区域运动神经元病频率的异质性：重点关注阿拉伯国家
Giancarlo Logroscino,Stefano Giannoni-Luza,Daniele Urso et al.
Giancarlo Logroscino et al.
Purpose of review: Although amyotrophic lateral sclerosis (ALS) epidemiology has been increasingly characterized in many regions, data from Arabic countries remain limited. This review aims to summarize the current knowle...
Gergo Erdi-Krausz,Pamela J Shaw
Gergo Erdi-Krausz
Purpose of review: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with few treatment options available. The approval of tofersen, an antisense oligonucleotide, for SOD1-ALS by the FDA and EMA ma...
Neurochemical biomarkers of amyotrophic lateral sclerosis: recent developments [0.03%]
肌萎缩侧索硬化症的神经化学生物标志物：最新进展
Federico Verde
Federico Verde
Review purpose: To provide an overview of the recent developments in the field of neurochemical biomarkers of amyotrophic lateral sclerosis (ALS). Recent ...
Christina Lang
Christina Lang
Purpose of review: This review summarizes recent evidence on sleep disturbances in amyotrophic lateral sclerosis (ALS), emphasizing their role as intrinsic features of the disease process rather than consequence of motor ...
The role of amino acid PET in the era of checkpoint inhibitors and targeted therapy for brain tumor treatment [0.03%]
免疫检查点抑制剂和靶向治疗时代脑肿瘤治疗中氨基酸PET的作用
Norbert Galldiks,Jana-Marie Peplinski,Manuel Kraft et al.
Norbert Galldiks et al.
Purpose of review: To summarize the role of diagnostic amino acid PET in the era of checkpoint inhibitors and targeted therapies for brain tumor treatment. ...