Tim J Hartung,Joseph Kuchling,Carsten Finke
Tim J Hartung
Purpose of review: Brain MRI is central to the diagnostic work-up of autoimmune encephalitis (AE). This review summarizes established patterns on routine MRI sequences across antibody-defined AE types and highlights emerg...
Cellular immunophenotyping in multiple sclerosis: advances and clinical implications [0.03%]
多发性硬化细胞免疫分型的进展及临床意义
Thiemo M Möllenkamp,Louisa Müller-Miny,Gerd Meyer Zu Hörste
Thiemo M Möllenkamp
Purpose of review: Multiple sclerosis is a clinically heterogeneous disease that is driven by complex immune mechanisms. This review summarizes recent methodological advances in immunophenotyping and discusses clinical im...
Paroxysmal movement disorders: an update on genetics, mechanisms, and emerging therapeutic strategies [0.03%]
阵发性运动障碍：遗传学、机制及新兴治疗策略的新进展
Maria Makrygianni,Robert Erro,Maria Stamelou
Maria Makrygianni
Purpose of review: This review will discuss the latest genetic and pathophysiological spectrum of paroxysmal movement disorders and emerging therapeutic strategies. ...
Autoimmune encephalitis and paraneoplastic neurologic syndrome: clinical diagnosis [0.03%]
自身免疫性脑炎和副肿瘤神经综合征的临床诊断
Soon-Tae Lee
Soon-Tae Lee
Purpose of review: Autoimmune encephalitis (AE) and paraneoplastic neurologic syndromes (PNS) are increasingly identified as causes of rapidly progressive immune-mediated neurologic syndromes. This review outlines diagnos...
Rosa Cortese,Alessia Bianchi,Nicola De Stefano
Rosa Cortese
Purpose of review: Recent advances in magnetic resonance imaging (MRI) have substantially expanded the ability to investigate multiple sclerosis (MS) pathobiology in-vivo. Beyond its diagnostic role, MRI now captures bloo...
Yotam Menuchin-Lasowski,Tanja Kuhlmann
Yotam Menuchin-Lasowski
Purpose of review: Current concepts suggest that relapse associated worsening as well as progression independent of relapse activity contributes to the long-term disability outcome of people with multiple sclerosis (MS). ...
Maria Trojano,Pietro Iaffaldano
Maria Trojano
Purpose of review: This review summarizes recent key advancements in multiple sclerosis (MS) achieved through the utilization of big data from diverse sources and advanced analytical techniques. ...
Gianmarco Bellucci,Sergio E Baranzini
Gianmarco Bellucci
Purpose of review: This review highlights the latest advances in the genetics of multiple sclerosis (MS). While earlier research defined the polygenic architecture of disease susceptibility, recent efforts have focused on...
Philippe Ryvlin,Daniel Friedman
Philippe Ryvlin