Eser Bulus,Ayse Altintas,Aksel Siva
Eser Bulus
Purpose of review: The diagnosis of multiple sclerosis (MS) is often challenging and misdiagnosis remains an important contemporary problem, with considerable consequences for patients. This review aims to specify the app...
Update on novel multiple sclerosis treatments: from dismal defeat to scintillating success [0.03%]
多发性硬化症的新疗法进展：从完全失败到巨大成功
Bruce Cree,Hans-Peter Hartung
Bruce Cree
Purpose of review: To review novel multiple sclerosis (MS) therapies currently in clinical trials. Recent findings: Sixty-seven clinica...
Maria A Rocca,Paolo Preziosa,Massimo Filippi
Maria A Rocca
Purpose of review: To summarize recent advancements in understanding multiple sclerosis (MS) pathophysiology, predicting disease course, and monitoring treatment responses using MRI. ...
Dongmei Jia,Fu-Dong Shi,Wei Jiang
Dongmei Jia
Purpose of review: This comprehensive overview summarized the latest advances of multiple sclerosis (MS) in China, including the diagnostic and treatment challenges, research and future directions under health policy reco...
Maurizio Severino,Mark W Green
Maurizio Severino
Purpose of review: The scope of this review is to discuss persistent aura without infarction, a rare, highly disabling, yet apparently benign clinical condition, straddling neurology, neuro-ophthalmology, and psychiatry, ...
Tuberculosis of the central nervous system: current concepts in diagnosis and treatment [0.03%]
中枢神经系统的结核病：诊断和治疗的新概念
Ravindra Kumar Garg
Ravindra Kumar Garg
Purpose of review: The outcome of central nervous system (CNS) tuberculosis has shown little improvement over several decades, with diagnosis remaining unconfirmed in nearly half of the cases. This review highlights curre...
Cecilia Friedrichs-Maeder,Grégory Lepeu,Maxime O Baud
Cecilia Friedrichs-Maeder
Purpose of review: Cortical excitability, defined as the cortex's responsiveness to incoming stimuli, is a fundamental concept in neuroscience and a targetable mechanism for controlling brain dysfunctions such as epilepsy...
Neha Lonkar,Eicke Latz,Róisín M McManus
Neha Lonkar
Purpose of review: Immunometabolism is an emerging field of research investigating the ability of immune cells to modulate their metabolic activity for optimal function. While this has been extensively examined in periphe...
SEEG in 2025: progress and pending challenges in stereotaxy methods, biomarkers and radiofrequency thermocoagulation [0.03%]
2025年的SEEG：脑立体定向技术、生物标志物及射频热凝面临的进展与挑战
Philippe Ryvlin
Philippe Ryvlin
Purpose of review: Technological innovations and clinical research in SEEG have dramatically increased with its worldwide dissemination. In this review, we summarize the main advances in the field from the last 5 years. ...