Andreas F Hottinger
Andreas F Hottinger
Purpose of review: In recent years, advances in the understanding of the regulatory mechanisms of the immune system has led to the development of new approaches for cancer treatment. Currently, immune checkpoint inhibitor...
Andreas F Hottinger
Andreas F Hottinger
Filip Scheperjans
Filip Scheperjans
Purpose of review: Gastrointestinal dysfunction is highly prevalent in Parkinson's disease and may precede motor symptoms by more than a decade. It has been proposed that the neurodegenerative cascade may actually be init...
Noninvasive brain stimulation after stroke: it is time for large randomized controlled trials! [0.03%]
中风后非侵入性脑刺激：是时候做大规模的随机对照试验了！
Christian Grefkes,Gereon R Fink
Christian Grefkes
Purpose of review: We here provide an update about studies published recently in the field of noninvasive neuromodulation of the motor system, aiming at facilitating recovery of function after stroke. ...
Behavioral self-management strategies for practice and exercise should be included in neurologic rehabilitation trials and care [0.03%]
神经康复试验和治疗中应包含行为的自我管理策略用于实践和锻炼
Bruce H Dobkin
Bruce H Dobkin
Purpose of review: Rehabilitation trials and postacute care to lessen impairments and disability after stroke, spinal cord injury, and traumatic brain injury almost never include training to promote long-term self-managem...
Stephanie Efthymiou,Andreea Manole,Henry Houlden
Stephanie Efthymiou
Purpose of review: Neuromuscular diseases are clinically and genetically heterogeneous and probably contain the greatest proportion of causative Mendelian defects than any other group of conditions. These disorders affect...
Alexander M Rossor,Pedro J Tomaselli,Mary M Reilly
Alexander M Rossor
Purpose of review: Charcot-Marie-Tooth disease (CMT) is one of the commonest inherited neuromuscular diseases with a population prevalence of 1 in 2500. This review will cover recent advances in the genetics and pathomech...
Olivier Benveniste,Werner Stenzel,Yves Allenbach
Olivier Benveniste
Purpose of review: Inflammatory myopathies are rare diseases. Their diagnosis criteria are historically based on their clinical phenotype (topography of the muscle weakness, presence of skin lesions and/or of extra-skin/m...
Matthew A White,Jemeen Sreedharan
Matthew A White
Purpose of review: Amyotrophic lateral sclerosis (ALS), like other neurodegenerative diseases, remains incurable, but gene mutations linked to ALS are providing clues as to how to target therapies. It is important for res...