Philippe Ryvlin,Daniel Friedman
Philippe Ryvlin
SUDEP update 2026: recent advances in experimental and clinical research [0.03%]
婴儿猝死综合征研究进展(2026)——实验与临床研究的新近成果
Philippe Ryvlin,Sylvain Rheims
Philippe Ryvlin
Purpose of review: This review summarizes experimental and clinical research advances in the field of sudden unexpected death in epilepsy (SUDEP) over the past 3 years. ...
Ann Subota,Colin B Josephson
Ann Subota
Purpose of review: Epilepsy increases risk of cardiovascular morbidity and mortality, and growing evidence suggests broader systemic effects, including on bone health. This review examines the evolving concepts of the "ep...
Harley Mocker,Jacob Pellinen,Christopher Elder
Harley Mocker
Purpose of review: This review discusses the current state of the evidence related to the relationship between the cerebellum and epilepsy, highlighting evidence on neurostimulation of the cerebellum for treatment of epil...
Celia Greenlaw,Coral M Stredny
Celia Greenlaw
Purpose of review: Autoimmune encephalitis-associated epilepsy (AEAE) is initially caused by an aberrant innate and/or adaptive immune system, and then the seizure nidus persists from the ensuing structural damage resulti...
Blood-based biomarkers of Alzheimer's disease: potential utility in clinical practice [0.03%]
血液生物标志物预测阿尔茨海默病的临床应用潜力
Xuemei Zeng,Nya Nicholson,Thomas K Karikari
Xuemei Zeng
Purpose of review: Blood-based biomarkers (BBMs) for Alzheimer's disease are beginning to enter clinical practice. As this integration advances, it is essential to critically examine their strengths, limitations, and read...
Integration over reduction: multimodal PET and fluid biomarkers in Alzheimer's disease and beyond [0.03%]
整合与简化:阿尔茨海默病及其他疾病的多模态PET和液体生物标志物
Marina Bluma,Konstantinos Chiotis,Agneta Nordberg
Marina Bluma
Purpose of review: Biomarker-based Alzheimer's disease (AD) diagnosis has shifted clinical practice from syndromic, dementia-stage diagnosis to a biologically defined framework anchored in amyloid positron emission tomogr...
Sophie Adler,Konrad Wagstyl
Sophie Adler
Purpose of review: Recent advances in the capabilities and usability of artificial intelligence (AI) architectures coupled with increased availability of neuroimaging datasets has fuelled a rapid expansion in AI applicati...
Clinical amyloid and tau positron emission tomography imaging in Alzheimer's disease: image interpretation in the era of anti-amyloid therapies [0.03%]
阿尔茨海默病时代的抗淀粉样蛋白疗法:PET 成像指导下的临床淀粉样蛋白和tau 病理学影像解读
Gregory Mathoux,Elif Harput,Débora E Peretti et al.
Gregory Mathoux et al.
Purpose of review: The introduction of disease-modifying anti-amyloid therapies has shifted the role of positron emission tomography (PET) imaging in Alzheimer's disease from confirming diagnosis to actively guiding clini...