Kiran Belani,G Burkhard Mackensen
Kiran Belani
Purpose of review: The purpose of this review is to detail the current state of utilization of echocardiographic modalities in structural heart disease interventions (transthoracic, transesophageal, and intracardiac), and...
Fie Juul Praastrup,Lone Nikolajsen,Camilla Gaarsdal Uhrbrand
Fie Juul Praastrup
Purpose of review: The purpose of this review is to summarize clinical evidence on intraoperative methadone, with emphasis on its analgesic efficacy, safety profile, and potential role within multimodal perioperative stra...
Conscientious objection [0.03%]
良心拒斥义务
Jennifer Lucero,Gail A Van Norman
Jennifer Lucero
Purpose of review: Modern medical ethics has prioritized patient rights and the importance of patient autonomy. This review article discusses the role conscientious objection plays within anesthesia while prioritizing the...
Suzetrigine, a selective NaV1.8 inhibitor in acute and chronic pain: mechanistic insights, clinical outcomes, and future perspectives [0.03%]
选择性钠离子通道NaV1.8抑制剂苏泽替尼在急性疼痛和慢性疼痛中的作用机制、临床疗效及未来前景展望
Steven L Chen,Matthew A Liu,Matthew W Swisher
Steven L Chen
Purpose of review: The opioid epidemic and limitations of current nonopioid analgesics have created a need for safer, effective pain therapies. Suzetrigine, a first-in-class selective NaV1.8 inhibitor, was approved by the...
Jonathan Gorky,Andres de Lima,Wanda M Popescu
Jonathan Gorky
Purpose of review: There is emerging literature suggesting that hyperoxia during anesthesia can lead to worse postoperative outcomes. We examine the subset of this literature pertaining to thoracic surgery, especially in ...
Delirium postcardiac surgery: etiologies and potential mitigation strategies [0.03%]
心脏手术后谵妄的原因及潜在的缓解策略
Jessica Y Rove,Mikita Fuchita,Hillary Lum et al.
Jessica Y Rove et al.
Purpose of review: Postoperative delirium remains one of the most common complications after cardiac surgery. This review summarizes the latest evidence on pathobiological mechanisms, prevention, and treatment of postoper...
Patients with adult congenital heart disease presenting for noncardiac surgery [0.03%]
成人先天性心脏病的非心脏手术患者的麻醉处理
Christian Refakis,Benjamin Marsh,Anjalee Dave et al.
Christian Refakis et al.
Purpose of review: With advances in surgical, medical, and anesthetic management, most patients born with congenital heart disease survive into adulthood. Patients with adult congenital heart disease (ACHD) present in inc...
Preoperative anemia in cardiac surgery patients: how to achieve clinical optimization - a narrative review [0.03%]
心脏手术患者的术前贫血：如何实现临床优化——综述性文章
Lena Saal-Bauernschubert,Amon Faske,Patrick Meybohm
Lena Saal-Bauernschubert
Purpose of review: Anemia is a common comorbidity in patients with cardiac disease, with iron deficiency accounting for approximately 80% of cases. Preoperative anemia has consistently been associated with increased morbi...
Will prothrombin complex concentrate replace plasma in cardiac surgical bleeding in North America? [0.03%]
凝血酶原复合物浓缩剂会取代北美心脏手术出血中的血浆吗？
Justyna Bartoszko,Nadia Gabarin,Kenichi Tanaka et al.
Justyna Bartoszko et al.
Purpose of review: There is increasing interest in four-factor prothrombin complex concentrate (4F-PCC) for treatment of acquired coagulopathic bleeding in cardiac surgery. Plasma, traditionally the treatment of choice, h...