Effects of DNA methylation and polygenic scores on self-reported suicidal ideation in psychoses: no evidence of epigenetic basis of polygenic risk [0.03%]
表观遗传学角度研究多态风险在精神疾病中的作用：未发现多基因风险的表观遗传学依据
George Nader,Matisse Ducharme,Philip Gerretsen et al.
George Nader et al.
Introduction: Schizophrenia is a significant clinical problem. Unfortunately, there are currently no biomarkers available for accurately identifying patients with schizophrenia who may be vulnerable to suicide. Because ge...
Prenatal diagnosis and genetic counselling of a de-novo 11p13p11.2 duplication with normal phenotype [0.03%]
染色体11p13p11.2新生重复致胎儿正常表型的产前诊断及遗传咨询
Xu Liu,Lan He,Yanting Chai et al.
Xu Liu et al.
Background: Proximal 11p duplication is often derived from a balanced translocation in a parent or inherited from a carrier (father or mother) with normal phenotype, and part of this duplication is a de-novo mutation. The...
The DNA methyltransferase complex conundrum: novel DNA methyltransferase 1 mutation in an Indian patient with dementia and sensory neural hearing loss on a background of long-standing psychosis [0.03%]
DNA甲基转移酶复合物难题：背景存在长期精神病的印度痴呆和感觉神经性听力损失患者的新型DNA甲基转移酶1突变
Mude Jeevan Naik,Pannaga Prasad Ganapathi,Manik Inder Singh Sethi et al.
Mude Jeevan Naik et al.
Epigenetic alterations, like DNA methylation, are increasingly recognised as integral to the development of both neurological and psychiatric disorders. Mutations in the DNA methyltransferase 1 (DNMT1) gene have also been linked to specific...
Genetic testing for susceptibility to major depressive disorder: a review of the behavioural repercussions of disclosing test results [0.03%]
抑郁症易感性的基因检测：披露结果的行为后果综述
Duru Kaya,Ulliana Savitskaya,Nicole Bloom
Duru Kaya
Predictive genetic testing for major depressive disorder (MDD) has become a widespread technological advancement to aid the process of early diagnosis and treatment selection. Despite these tests' growing accessibility to the public, scant ...
How do your genes feel? A qualitative investigation of subjective experience of anorexia nervosa in patients with high vs. low polygenic risk [0.03%]
基因感受如何？一项关于高多基因风险和低多基因风险厌食症患者的主观体验定性调查研究
Katarina Lindstedt,Elin Monell,Andreas Birgegård et al.
Katarina Lindstedt et al.
Objective: Genome-wide association studies (GWAS) implicate psychiatric, metabolic, and anthropometric factors in anorexia nervosa. We developed an 'experiential genetics' design, layering qualitative methodology atop GWA...
Expression of miR-195-5p in the serum of children with autism spectrum disorder and its correlation with the severity of the disease [0.03%]
自闭症患儿血清中miR-195-5p表达及与病情严重程度的关系研究
Jielin Gao,Yafei Hou,Jie Mao et al.
Jielin Gao et al.
Objective: The target of this research was to explore the serum miR-195-5p expression in children with autism spectrum disorder (ASD) and its association with the disease severity. ...
A 19q13 microdeletion syndrome presenting with punding, frangophilia, hypermetamorphosis, frontal lobe and vermal hypoplasia, with depression misdiagnosed as schizophrenia, treated with mirtazapine [0.03%]
以强迫性筑巢症、对法语的病态爱恋和过度翻箱倒柜行为为特征的19q13微缺失综合征，伴有额叶和小脑蚓部发育不全，误诊为精神分裂症的抑郁症使用米氮平治疗
João Gama Marques,Josef Finsterer
João Gama Marques
Chromosome 19q13 microdeletion syndrome is a rare genetic disorder characterized by prenatal and postnatal growth retardation, intellectual disability, expressive language impairment, ectodermal dysplasia, and slender habitus. We present a ...
Reflections on schizophrenia and genetics: a response to Gama Marques and Finsterer [0.03%]
关于精神分裂症和遗传学的反思：对Gama Marques和Finsterer的回应
Luis M Rojo-Bofill,Cecilia Sanjuan-Ortiz,Monica Rosello et al.
Luis M Rojo-Bofill et al.
How the human genome project has increased the prevalence of pseudoschizophrenia and decreased the prevalence of true schizophrenia? [0.03%]
人类基因组计划如何增加了假 schizophrenia 的流行率并降低了真 schizophrenia 的流行率？
João Gama Marques,Josef Finsterer
João Gama Marques