Depression severity and efficacy outcomes: post hoc analyses from a phase 3 trial of esmethadone for the adjunctive treatment of major depressive disorder with inadequate response to standard antidepressants [0.03%]
氟西丁联合托莫西汀治疗难治性抑郁症的III期临床试验：预设亚组分析
Clotilde Guidetti,George I Papakostas,Steven Stahl et al.
Clotilde Guidetti et al.
Esmethadone is under development as an adjunctive treatment for major depressive disorder in patients with inadequate response to standard antidepressants. In the phase 3 study REL-1017-301, esmethadone did not meet the primary endpoint of ...
An observational study on the effects of as-needed use of various antipsychotic drugs for agitation due to psychotic disorders [0.03%]
一项研究精神疾病所致激越症时按需使用各种抗精神病药物效果的观察性研究
Kotaro Hatta,Fumiyoshi Morikawa,Satoshi Yamasaki et al.
Kotaro Hatta et al.
This multicenter, 6-month naturalistic observational study investigated the time from as-needed (PRN) administration of psychotropic medications to the onset of calming in patients with acute psychotic disorders. Newly admitted patients exh...
Patient treatment preference as a predictor of clinical outcomes in subjects with treatment-resistant depression: a comparative effectiveness research trial for antidepressant incomplete and nonresponders with treatment-resistant depression (ASCERTAIN-TRD) [0.03%]
预测治疗抵抗性抑郁患者临床疗效的患者治疗偏好：抗抑郁药部分反应和无反应治疗抵抗性抑郁患者的比较有效性研究（ASCERTAIN-TRD）
Stefania Chaikali,Clotilde Guidetti,Madhukar H Trivedi et al.
Stefania Chaikali et al.
Major depressive disorder (MDD) is a severe and debilitating illness. Despite the available treatments, clinical outcomes remain suboptimal, and hence, it is crucial to identify predictive factors for response. This is a secondary analysis ...
Unspoken needs: an essential perspective in the treatment of schizophrenia [0.03%]
不容忽视的隐性需求——治疗精神分裂症的一个重要视角
Alessandra Martinelli,Giovanni de Girolamo
Alessandra Martinelli
Despite increasing attention to patient-centered care, the treatment of schizophrenia remains predominantly clinician-driven, with limited integration of patients' subjective needs. This paper critically examines the concept of unmet needs ...
The effects of lurasidone on five symptom domains and individual items in schizophrenia: Post-hoc analysis from Phase 3 study [0.03%]
鲁拉西酮对五个症状领域及单项在精神分裂症中的影响：来自III期研究的事后分析
Itaru Miura,Kentaro Takai,Shunji Toya et al.
Itaru Miura et al.
The aim of this analysis was to examine the impact of treatment with lurasidone on a broad range of symptoms during an acute episode of schizophrenia. In patients with an acute exacerbation of schizophrenia treated with lurasidone in a 6-we...
Beyond symptom reduction: targeting cognitive deficits in obsessive-compulsive disorder treatment [0.03%]
超越单纯缓解症状：正视强迫症治疗中的认知缺陷
Sam Rashkovich,Ganeev Singh,Eric Hollander
Sam Rashkovich
Same outcome, different walls: rethinking comparisons in prison suicide research [0.03%]
殊途同归：重新思考监狱自杀研究中的比较问题
Raffaella Calati,Franca Crippa,Stefano Tambuzzi et al.
Raffaella Calati et al.
Transcranial direct current stimulation and cognitive modifiability in obsessive compulsive disorder: a reaction to recent findings by Pellegrini et al [0.03%]
经颅直流电刺激和强迫症的认知可塑性：对Pellegrini等最近研究结果的评论
Rodolfo Leuzzi,Bernardo Dell&#x;Osso
Rodolfo Leuzzi