Molecular docking, dynamics and free energy analyses of Acinetobacter baumannii OXA class enzymes with carbapenems investigating their hydrolytic mechanisms [0.03%]
鲍曼不动杆菌OXA酶与碳青霉烯类抗生素分子对接、动力学和自由能分析，探究其水解机制
Balajee Ramachandran,Jeyaraman Jeyakanthan,Bruno S Lopes
Balajee Ramachandran
Introduction. Acinetobacter baumannii is a critical priority pathogen listed by the World Health Organization due to increasing levels of resistance to carbapenem classes of antibiotics. It causes wound and other nosocomial infections, whic...
Molecular characterization of respiratory syncytial virus circulating in Tunisia between 2015 and 2018 [0.03%]
2015至2018年在突尼斯流行的呼吸道合胞病毒的分子特征分析
Amira Jerbi,Imene Fodha,Meriam Ben Hamida-Rebai et al.
Amira Jerbi et al.
Introduction. Respiratory syncytial virus (RSV) is the most frequently identified viral agent in children with lower respiratory tract infection (LRTI). No data are available to date regarding RSV genotypes circulating in Tunisia.Aim. The a...
Molecular detection of Mycobacterium tuberculosis in poor-quality cough specimens [0.03%]
低质量咳嗽标本中结核分枝杆菌的分子检测
Tondani A Mboneni,Owen O Eales,Ntsoaki L Mosina et al.
Tondani A Mboneni et al.
Clinical specimens unfit for laboratory processing represent missed opportunities for diagnosing tuberculosis. Poor-quality cough specimens (n=61) from presumptive tuberculosis cases were cultured and GeneXpert MTB/RIF (Xpert) successfully ...
Validation of a single-step, single-tube reverse transcription loop-mediated isothermal amplification assay for rapid detection of SARS-CoV-2 RNA [0.03%]
用于快速检测SARS-CoV-2 RNA的一步法单管逆转录环介导等温扩增测定的验证
Jean Y H Lee,Nickala Best,Julie McAuley et al.
Jean Y H Lee et al.
Introduction. The SARS-CoV-2 pandemic of 2020 has resulted in unparalleled requirements for RNA extraction kits and enzymes required for virus detection, leading to global shortages. This has necessitated the exploration of alternative diag...
The epidemiology and molecular characteristics of linezolid-resistant Staphylococcus capitis in Huashan Hospital, Shanghai [0.03%]
上海华山医院克林霉素抗性表皮葡萄球菌的流行病学和分子特征研究
Li Ding,Pei Li,Yang Yang et al.
Li Ding et al.
Introduction. Linezolid-resistant (LZR) Staphylococcus capitis has recently emerged in our hospital, and its potential resistance mechanisms are still not clear.Aim. This study aimed to investigate the epidemiology, clinical and genetic cha...
Molecular characterization of a novel bla CTX-M-3-carrying Tn 6741 transposon in Morganella morganii isolated from swine [0.03%]
来自猪的摩根菌中产生新型bla CTX-M-3基因的Tn 6741转座子的分子特性分析
Xingwei Luo,Yajun Zhai,Dandan He et al.
Xingwei Luo et al.
Introduction. The bla CTX-M-3 gene has rarely been reported in Morganella morganii strains and its genetic environment has not yet been investigated.Aim. To identify the bla CTX-M-3 gene in M. morganii isolated from swine and characterize i...
Streptomyces from traditional medicine: sources of new innovations in antibiotic discovery [0.03%]
来源于传统医药的链霉菌：抗生素研究中新颖的创新来源
Gerry A Quinn,Aiya M Banat,Alyaa M Abdelhameed et al.
Gerry A Quinn et al.
Given the increased reporting of multi-resistant bacteria and the shortage of newly approved medicines, researchers have been looking towards extreme and unusual environments as a new source of antibiotics. Streptomyces currently provides m...
Does sub-culturing of positive MRSA blood cultures affect vancomycin MICs? [0.03%]
体外分传阳性MRSA菌血培养是否会影响万古霉素的最小抑菌浓度？
Izumo Kanesaka,Takamitsu Ito,Ritsuko Shishido et al.
Izumo Kanesaka et al.
Introduction. Empirical vancomycin (VAN) treatment failure for methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia, with significantly higher mortality, has been reported for MRSA strains with reduced VAN susceptibility.Aim. Our ...
Comparative Study
Journal of medical microbiology. 2020 Aug;69(8):1095-1099. DOI:10.1099/jmm.0.001225 2020
Improved treatment strategies can result in better outcomes following one-stage exchange surgery for MRSA periprosthetic joint infection [0.03%]
改良的治疗策略可以改善MRSA假体周围关节感染一期翻修手术的效果
Malte Ohlmeier,Sergei Filitarin,Giorgio Delgado et al.
Malte Ohlmeier et al.
Introduction. Periprosthetic joint infections caused by methicillin-resistant Staphylococcus aureus (MRSA-PJIs) are rare, with only a few studies reporting the treatment outcomes and even fewer reporting outcomes with one-stage exchange.Aim...
The One Health European Joint Programme (OHEJP), 2018-2022: an exemplary One Health initiative [0.03%]
2018-2022年“欧盟一体健康联合计划”（OHEJP）：一项典范的“一体健康”行动
Helen L Brown,Jade L Passey,Maria Getino et al.
Helen L Brown et al.