A viable but nonculturable state of Mycobacterium avium in response to macrolide antibiotics: a recipe for relapses? [0.03%]
鸟分枝杆菌对大环内酯类抗生素的休眠反应：复发的原因？
Iris Schuiermanni,Eva Terschlüsen,Henrieke de Man et al.
Iris Schuiermanni et al.
Mycobacterium avium complex disease is difficult to treat, with high failure and recurrence rates despite multidrug, macrolide-based treatments. The bacterial mechanisms involved in this drug tolerance and persistence are incompletely under...
A testing time for gradient strips: an evaluation of ETEST for the antimicrobial susceptibility testing of Neisseria gonorrhoeae [0.03%]
新病原体检验方法评价：奈瑟氏淋球菌的ETEST药敏试验检测评估研究
Rachel Pitt-Kendall,Jack Minshull,Sandhya Vivekanand et al.
Rachel Pitt-Kendall et al.
Introduction. Antimicrobial susceptibility testing (AST) of Neisseria gonorrhoeae isolates is recommended in the UK to ensure antimicrobial stewardship and detection of multi-drug and extensively resistant cases. In diagnostic and reference...
Robert J Shorten,Katharine Hayden,Mathew A Diggle
Robert J Shorten
A nanoluciferase-tagged Schmallenberg virus (SBV): an efficient tool for measuring and tracking viral infection dynamics [0.03%]
一种纳米型荧光素酶标记的施马尔巴赫病毒（SBV）：一种有效测量和追踪病毒感染动力学的工具
Franziska Sick,Andrea Aebischer,Martin Beer et al.
Franziska Sick et al.
Introduction. Schmallenberg virus (SBV) is an arthropod-borne virus and belongs to the Simbu serogroup within the family Peribunyaviridae, genus Orthobunyavirus. Infection of naïve ruminants at critical stages of gestation can result in se...
Reduction of resources with mRNA host-response whole blood testing on patients presenting to the emergency department with suspected infections: a retrospective analysis of 30 cases [0.03%]
基于mRNA宿主反应全血检测的急诊疑似感染患者资源消耗减少：一项回顾性分析
Alan H B Wu,Shane Falcinelli,Rama Yakubu
Alan H B Wu
Introduction. The TriVerity™ test (Inflammatix Inc.) uses the patient's mRNA expression patterns from whole blood to provide a site-agnostic likelihood of bacterial infection and/or viral infection. The test also reports an illness severit...
Correlation in the change of gut microbiota with clinical periodontal parameters in grade C periodontitis patients after non-surgical periodontal therapy [0.03%]
非手术牙周治疗后CPC患者口腔临床参数变化与肠道菌群的相关性研究
Elif Mutafcilar Velioglu,Uğur Arslan,Seyit Ali Kayis et al.
Elif Mutafcilar Velioglu et al.
Introduction. Intestinal dysbiosis is associated with systemic health, and approaches targeting the microbiome can influence the host. Oral and intestinal microbiota are interrelated; therefore, we aimed to determine whether non-surgical pe...
The lingering legacy of one letter in antimicrobial susceptibility testing [0.03%]
抗生素药物敏感性试验中一个字母影响的长久遗留问题
Saied Ali,Fidelma Fitzpatrick
Saied Ali
For decades, the 'Intermediate' (I) category in antimicrobial susceptibility testing was frequently misinterpreted as indicative of therapeutic failure, rather than an opportunity for dose optimization. This misunderstanding shaped prescrib...
Surveillance of genomic diversity and antimicrobial resistance in enterotoxigenic Escherichia coli in England, 2015-2023 [0.03%]
英格兰2015-2023年肠毒素型大肠杆菌基因组多样性和抗菌药物耐药性的监测
Delia-Gabriela Grigoruta,Ching-Ying J Poh,Ella V Rodwell et al.
Delia-Gabriela Grigoruta et al.
Introduction. Enterotoxigenic Escherichia coli (ETEC) are one of the leading causes of gastrointestinal infections globally, primarily affecting children in low- and middle-income countries and travellers to endemic regions.Gap Statement. T...
Induction of lipid A modification genes in Pseudomonas aeruginosa cells tolerant to a commercially available contact lens disinfection solution [0.03%]
铜绿假单胞菌的耐药性与其脂多糖lipid A修饰有关
Yasmin Hilliam,Stuart D Armstrong,R F Langendonk et al.
Yasmin Hilliam et al.
Introduction. Pseudomonas aeruginosa has a high propensity to develop drug resistance and is a leading cause of bacterial keratitis, particularly amongst contact lens (CL) wearers. Although CL wearers are advised to regularly disinfect thei...
Unravelling three-way interactions between Clostridioides difficile, microbiota and the host [0.03%]
解密艰难梭菌、微生物组和宿主三者之间的相互作用关系
Kavana K Bywater-Brenna,Meera Unnikrishnan
Kavana K Bywater-Brenna
Clostridioides difficile infection is a global issue, representing a huge financial burden on healthcare systems worldwide which is further exacerbated by high recurrence rates. Infection is closely linked with the gut microbiome status, wi...