CD36 and SR-B1 polymorphisms exhibit distinct association patterns in active and latent tuberculosis [0.03%]
CD36和SR-B1多态型在活动性和潜伏性结核病中的关联模式不同
Ezza Binte Tariq,Urooj Subhan,Farah Deeba et al.
Ezza Binte Tariq et al.
Introduction. Host genetics plays a pivotal role in determining disease susceptibility among individuals infected with Mycobacterium tuberculosis. Scavenger receptors (SRs) such as CD36 and SR-B1 mediate pathogen recognition and lipid uptak...
David Broderick,Kristi Biswas,Raymond Kim et al.
David Broderick et al.
Introduction. Biofilms have been implicated as a potential cause of chronic rhinosinusitis (CRS), with patients showing an increased prevalence of biofilms, likely contributing to antibiotic ineffectiveness in these individuals. In many env...
Potential confounding factors in currently used antibiotic susceptibility assays for the honey bee pathogen Melissococcus plutonius [0.03%]
用于蜜蜂病原体Melissococcus plutonius的当前抗生素敏感性测定的潜在干扰因素
Peter Fowler,Robyn Hawley,Meghan O Milbrath
Peter Fowler
Introduction. Melissococcus plutonius is the causative agent of European foulbrood (EFB), a disease of honey bees that is endemic in many areas of the USA. Only one antibiotic, oxytetracycline (OTC), is approved for EFB management, and ther...
Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in paediatric patients in Japan (2020-2023) [0.03%]
日本儿科患者中肺炎链球菌血清型分布及抗生素耐药性（2020-2023）
Satoshi Nakano,Takao Fujisawa,Shota Koide et al.
Satoshi Nakano et al.
Introduction. Streptococcus pneumoniae remains a major pathogen causing invasive diseases in children worldwide. Although pneumococcal conjugate vaccines (PCVs) have significantly reduced the disease burden, non-vaccine serotypes and antimi...
The synergistic pathogenic mechanism of Brucella melitensis M5-90 effector protein BspC in regulating host cell apoptosis, inflammation and oxidative stress [0.03%]
布鲁氏菌M5-90效应蛋白BspC调节宿主细胞凋亡、炎症和氧化应激的协同致病机制
Shuanghong Yin,Li Li,Lan Zhu et al.
Shuanghong Yin et al.
Introduction. Brucellosis is a zoonotic contact infectious disease caused by Brucella. Recently, researchers screened a series of Brucella effector proteins and identified the functions of most of them, which play important roles in the int...
Targeted detection of Helicobacter pylori resistance to clarithromycin and levofloxacin using single-cell Raman spectroscopy [0.03%]
单细胞拉曼光谱技术检测幽门螺旋菌克拉霉素和左氧氟沙星耐药性
Ziman Wu,Xinying Li,Xiaowen Dou et al.
Ziman Wu et al.
Introduction. Helicobacter pylori infection is a major global health concern, and its increasing antibiotic resistance poses significant challenges to eradication therapy. Traditional methods for detecting H. pylori resistance are time-cons...
The role of molecular diagnostics in pleural empyema: insights from a 4-year analysis of microbial trends and antimicrobial use [0.03%]
分子诊断在胸腔脓肿中的作用：来自4年分析的微生物趋势和抗菌药物使用的启示
Amy Carroll,Emma McGuire,Pietro Coen et al.
Amy Carroll et al.
Introduction. Pleural empyema is common but microbiological diagnosis is challenging, often leading to prolonged empiric broad-spectrum antimicrobial use.Hypothesis. 16S rRNA PCR on operative pleural tissue will increase diagnostic yield an...
Clinical outcomes and risk factors associated with bloodstream infections caused by multidrug-resistant Gram-negative bacteria in hospitalized patients: a prospective cohort study in Libya [0.03%]
利比亚住院患者由多重耐药革兰阴性菌导致血流感染的临床结局及危险因素：前瞻性队列研究
Mohanned Mohamed Alwashaish
Mohanned Mohamed Alwashaish
Introduction. Bloodstream infections (BSIs) caused by multidrug-resistant Gram-negative bacteria (MDR-GNB) are a major cause of mortality, with limited treatment options.Gap/Hypothesis. Despite the global rise of MDR-GNB, prospective data o...
Mechanism of azole resistance in Candida glabrata isolates from India: clinical vs. induced perspectives [0.03%]
印度光滑假丝酵母菌株唑类抗药性机制：临床与诱导视角的区别
Kalpana Pawar,Ashutosh Singh
Kalpana Pawar
Introduction. Candida glabrata is a pathogenic yeast in humans, recognized for its genomic plasticity and increasing prevalence of antifungal resistance, including multidrug-resistant phenotypes, especially in the US and European countries....
In vitro efficacy of disinfectants against Cutibacterium acnes [0.03%]
消毒剂对Cutibacterium acnes体外效力的研究
Koyo Yoshihara,Shoji Seyama,Juri Koizumi et al.
Koyo Yoshihara et al.
Introduction. The abnormal proliferation of Cutibacterium acnes, a human skin commensal bacterium, aggravates acne. Prompt and aggressive treatment of acne in its initial stages is essential because of the increased psychological distress e...