Rapid deprotection and purification of ceftaroline free base from its phosphoramidate prodrug [0.03%]
卡巴匹林酸磷酰胺前药去保护和净化生成卡巴匹林酸盐基快速方法研究
Souvik Roy,Robert D Kina,Nathaniel N Koloian et al.
Souvik Roy et al.
Contemporary pharmaceutical design often incorporates functional groups to improve the pharmacokinetic/pharmacodynamic profile of a desired active chemical entity. These compounds are known as prodrugs. While prodrug enhancements may improv...
Corrigendum: Genomic characterization of Haemophilus influenzae harbouring an exogenous resistance gene [0.03%]
高致病性流感嗜血杆菌中寄生的外源耐药基因的基因组特征纠正说法
Emi Tanaka,Takeaki Wajima,Sonoe Hirano et al.
Emi Tanaka et al.
Published Erratum
Journal of medical microbiology. 2025 Sep;74(9):002075. DOI:10.1099/jmm.0.002075 2025
Corrigendum: Fosfomycin resistance in extended-spectrum beta-lactamase producing Escherichia coli isolated from urinary tract-infected patients in a tertiary care hospital [0.03%]
氟喹诺酮类和头孢菌素类抗菌药物敏感的超广谱β-内酰胺酶产 fosfomycin-resistant产ESBL大肠杆菌菌株在中国医院感染患者的尿液中频繁出现的备注公告
Priksha Thakur,Narinder Kaur,Shubham Chauhan et al.
Priksha Thakur et al.
Published Erratum
Journal of medical microbiology. 2025 Sep;74(9). DOI:10.1099/jmm.0.002076 2025
Role and mechanism of hexyl-aminolevulinate ethosome-mediated antimicrobial photodynamic therapy in reversing fluconazole resistance in Nakaseomyces glabrata (Candida glabrata) [0.03%]
他莫昔芬逆转Nakaseomyces glabrata(Candida glabrata)对氟康唑耐药性的作用及机制:叶酸受体介导的乙醇胺-壳聚糖包载阿霉素脂质体的作用
Yingzhe Wang,Yingting Huang,Wei Long et al.
Yingzhe Wang et al.
Introduction. Azoles are extensively employed as clinical antifungal agents; however, their long-term and widespread application contributed to the progressive emergence of azole resistance. A significant increase in infections caused by az...
Alexandre Giraud-Gatineau,Kouessi Dagbo,Helena Pětrošová et al.
Alexandre Giraud-Gatineau et al.
Leptospirosis is a re-emerging zoonosis caused by a diverse range of pathogenic Leptospira, which are divided into species, serogroups and serovars. Although advances in genomics have recently refined species classification, serotyping, whi...
Parasitology of the twenty-first century: are we moving in the right direction? [0.03%]
21世纪的寄生虫学:我们是否走在正确的道路上?
Kinga Kowalewska-Grochowska,Romina Reyes,Pauline Tomlin
Kinga Kowalewska-Grochowska
For thousands of years, parasitic infections have represented a constant challenge to human health. Despite constant progress in science and medicine, the challenge has remained mostly unchanged over the years, partly due to the vast comple...
Combination effect of meropenem and antifungals against Escherichia coli- Candida albicans dual-species biofilms in vitro and in vivo using a silkworm model [0.03%]
甲氧苄氨嘧啶与抗真菌药对大肠杆菌-白色念珠菌双物种生物被膜的联合效应:体外及体内(家蚕模型)研究
Sanae Kurakado,Kakeru Yasuda,Yasuhiko Matsumoto et al.
Sanae Kurakado et al.
Introduction. Biofilms are a primary form of device-associated infections and typically exhibit high tolerance to antimicrobial agents. In biofilms formed by multiple microbial species, microorganisms may show even greater tolerance, compli...
Effects of novel organoantimony compounds on the fungal pathogen Cryptococcus neoformans [0.03%]
新型 organoantimony化合物对真菌病原体Cryptococcus neoformans的影响
Kaitlyn Cotton,Jacob A Lieberman,Nikolay Gerasimchuk et al.
Kaitlyn Cotton et al.
Introduction. Cryptococcus neoformans is an opportunistic fungal pathogen that causes pulmonary cryptococcosis, or an acute or chronic infection in the lungs, and cryptococcal meningitis, an infection of the brain and spinal column, in immu...
Enhancing mortality prediction in AIDS and disseminated Talaromyces marneffei: the impact of novel inflammatory markers in a nomogram [0.03%]
预测艾滋病和马尔尼菲青霉病死亡率的影响因素及预警模型的建立
Yan Zhang,Xia Zhang,Huaizhong Cui et al.
Yan Zhang et al.
Introduction. Talaromyces marneffei (TM) is a common opportunistic infection among patients with AIDS, characterized by rapid systemic dissemination and a high mortality rate. Early identification of patients at risk of death is critical to...
Overview of US public health laboratory leadership development programmes and implementation opportunities [0.03%]
美国公共卫生实验室领导力发展项目概述及实施机遇
Emily L McCutchen,Kathleen A Street,Amanda M Harvey
Emily L McCutchen
Introduction. The public health laboratory system in the United States (USA) is extensive and focuses on the health of the nation's population by providing testing for the identification and spread mitigation of public health concerns. Test...