Tislelizumab combined with gemcitabine plus cisplatin for muscle-invasive upper tract urothelial carcinoma: A retrospective single-center cohort analysis [0.03%]
替雷利珠单抗联合吉西他滨和顺铂治疗肌层浸润性上尿路尿路上皮癌：一项单中心队列回顾性分析研究
Jingwen Zhang,Yongshuang Xiao,Donghua Cai et al.
Jingwen Zhang et al.
ObjectiveGemcitabine plus cisplatin is the standard adjuvant regimen for postoperative management of muscle-invasive upper tract urothelial carcinoma. This study investigated whether adding tislelizumab to gemcitabine plus cisplatin improve...
Serum high-density lipoprotein partially mediates the inverted L-shaped association between estimated glucose disposal rate and risk of kidney stones: A cross-sectional study from National Health and Nutrition Examination Survey [0.03%]
基于NHANES的横断面研究：估计葡萄糖处置率与肾结石风险之间呈倒L形关联，血清高密度脂蛋白部分介导了这一关联
Junzhi Liu,Xiaoyi Li,Kun Xu et al.
Junzhi Liu et al.
ObjectiveKidney stones, affecting approximately 10% of adults worldwide, pose substantial clinical and economic burdens. Although insulin resistance is implicated in lithogenesis, the association between estimated glucose disposal rate, a s...
Involvement of increased arginase-1+ group 2 innate lymphoid cells and myeloid-derived suppressor cells in endometrial carcinoma: A pilot study [0.03%]
增高的精氨酸酶-1阳性先天性淋巴细胞亚群和髓源性抑制细胞在子宫内膜癌中作用的初步研究
Zhangyun Gong,Zhimin Lu,Anan Pan et al.
Zhangyun Gong et al.
BackgroundEndometrial carcinoma is a prevalent gynecologic malignancy with a relatively low survival rate. Emerging studies have demonstrated that crosstalk between group 2 innate lymphoid cells (ILC2s) and myeloid-derived suppressor cells ...
Predicting time-to-event outcomes in critically ill patients with intracerebral hemorrhage using machine learning [0.03%]
利用机器学习预测脑内出血危重患者的事件时间结局
Jianhua Chen,Mengjie Wang,Xiaoqin Xia et al.
Jianhua Chen et al.
BackgroundIntracerebral hemorrhage is associated with high mortality in intensive care settings. Current prognostic models have limitations, including poor interpretability and insufficient validation in critically ill populations. In this ...
External iliac artery thrombosis following open reduction of acetabular fracture by para-rectus approach: A case report [0.03%]
经旁正中入路髋臼骨折切开复位后的髂外动脉血栓形成：1例报告
Wenlian Song,Kecheng Lao,Jinli Chen et al.
Wenlian Song et al.
BackgroundExternal iliac artery thrombosis is a rare vascular complication that can result in a series of serious adverse outcomes. Existing studies on external iliac artery thrombosis after open reduction of acetabular fracture have primar...
Li Juan,Chen Weiping
Li Juan
The objective of this study was to investigate the clinical characteristics and underlying causes of misdiagnosis in pulmonary granulomas, analyze the diagnostic challenges and differential diagnostic process, and improve clinical understan...
Clinical applications of esketamine: Current status and future perspectives [0.03%]
艾斯氯胺酮的临床应用：现状与未来展望
Hui Li,Jingjing Deng,Tao Liu et al.
Hui Li et al.
Ketamine, a dissociative anesthetic, has been extensively used in clinical anesthesia and sedation. However, its use in general anesthesia is gradually declining because of numerous adverse effects. In 2019, esketamine was introduced to the...
Clinical application and optimization strategies for antibody-drug conjugates in solid tumors [0.03%]
抗体偶联药物在实体瘤中的临床应用及优化策略
Jie Qu,Xiaoyue Zhao,Linzhu Zhang et al.
Jie Qu et al.
Despite the availability of multiple treatments for solid tumors, the prognosis of advanced solid tumors remains poor. Antibody-drug conjugates, a novel type of antitumor drugs, which are created by conjugating cytotoxic small-molecule drug...
Association between the Zhejiang University index and metabolic dysfunction-associated fatty liver disease as analyzed in National Health and Nutrition Examination Survey: A retrospective observational study [0.03%]
基于NHANES的浙江大学指数与代谢失调相关脂肪肝病关联的回顾性观察研究
Wei Fu,Xiaoyue Wu,Guobin Cheng et al.
Wei Fu et al.
ObjectiveTo evaluate the association between the Zhejiang University index, a composite metabolic indicator, and the risk and severity of metabolic dysfunction-associated fatty liver disease.MethodsThis cross-sectional study utilized data f...
Development and validation of a dynamic prognostic score for hepatitis B virus-related acute-on-chronic liver failure [0.03%]
乙型肝炎病毒相关急性-on-慢性肝功能衰竭的预后评分体系的建立和验证
Jiemenglu Li,Jian Yang,Chunyan Jiang et al.
Jiemenglu Li et al.
ObjectiveHepatitis B virus-related acute-on-chronic liver failure is a rapidly progressive syndrome associated with high mortality. The aim of this study was to develop a dynamic prognostic score for precise outcome prediction in patients w...