Association between COVID-19 status and Leydig cell functional capacity among men in hospitalized cohorts [0.03%]
新冠肺炎住院男性患者的生殖内分泌变化及睾丸间质细胞功能受损的横断面研究
Ravinder Anand-Ivell,Xinyuan Yang,Alexander W Tarr et al.
Ravinder Anand-Ivell et al.
Background: The first wave of the COVID-19 pandemic in the UK in 2020 led to significant morbidity, hospitalization, and death, particularly amongst elderly men. Recent meta-analyses confirmed that SARS-CoV-2 infection le...
Correlations between the cumulative metabolic score for visceral fat and its dynamic trajectories with the onset of cardiovascular disease in middle-aged and older adults: findings from two prospective cohorts [0.03%]
关于内脏脂肪累积代谢评分及其动态轨迹与中老年人心血管病发病关联的前瞻性队列研究
Lisi Xu,Miao Sun
Lisi Xu
Background: Cardiovascular disease (CVD) remains a leading cause of global mortality. The metabolic score for visceral fat (Mets-VF) integrates metabolic dysfunction and visceral adiposity, yet the effects of its long-ter...
Age-related patterns in prostate cancer: epidemiology, pathology, treatment, and survival [0.03%]
前列腺癌的年龄相关模式：流行病学、病理学、治疗和生存状况
Xin Zhang,Chuanlin Wang,Sen Pan et al.
Xin Zhang et al.
Background: Contemporary, systematic comparisons of prostate cancer (PCa) across the entire age spectrum regarding incidence, pathology, treatment, and long-term outcomes remain lacking. ...
A systems biology approach to identify common molecular signatures in Hashimoto's thyroiditis and rheumatoid arthritis [0.03%]
系统生物学方法识别桥本甲状腺炎和类风湿关节炎的共同分子标志物
Jian-Bin Wei,Yuan Lin,Qing-Ying Xu et al.
Jian-Bin Wei et al.
Background: Hashimoto's thyroiditis (HT) and rheumatoid arthritis (RA) are prevalent autoimmune disorders with substantial clinical overlap, yet the shared molecular mechanisms underlying their comorbidity remain poorly u...
Real-world outcomes of tadalafil plus mirabegron combination therapy in men with lower urinary tract symptoms and overactive bladder symptoms: a retrospective cohort study [0.03%]
坦洛新联合米拉贝隆治疗下尿路症状及过度活动膀胱综合征的疗效分析：回顾性队列研究
Abdurrahman İnkaya,Hasan Samet Güngör
Abdurrahman İnkaya
Background: Men with mixed lower urinary tract symptoms (LUTS) often have storage symptoms that drive bother and quality-of-life impairment. Evidence on tadalafil plus mirabegron in routine clinical practice is limited. ...
Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS) [0.03%]
基于美国食品药品监督管理局不良事件报告系统（FAERS）的真实世界不良事件的 disproportionality 分析：评估 α-1 受体阻滞剂、5α 还原酶抑制剂和 PDE5I 治疗前列腺增生的安全性特征
Zihao Zhao,Changjing Wu,Yang Xiong et al.
Zihao Zhao et al.
Objective: To compare the real-world safety profiles of α1-adrenoceptor antagonists (α1-blockers), 5α-reductase inhibitors (5ARIs), and phosphodiesterase type 5 inhibitor (PDE5I) used in the treatment of benign prostat...
Development and validation of machine learning prognostic models for overall survival in non-surgical prostate cancer patients with bone metastases [0.03%]
开发并验证非手术前列腺癌骨转移患者整体生存期的机器学习预测模型及其验证研究
Qilin Yang,Ben Wang,Yang Yang et al.
Qilin Yang et al.
Objective: To construct and interpret a machine learning model for predicting overall survival in nonsurgical prostate cancer with bone metastases (PCBM). ...
Immune-mediated pathways between red blood cell traits and prostate cancer: a causal relationship network based on Mendelian randomization evaluation [0.03%]
基于孟德尔随机化评估的红细胞表型与前列腺癌之间免疫介导的路径及因果关系网络分析
Ting Yang,Jinyu Zhang,Jiongzheng Li et al.
Ting Yang et al.
Background: Although both the immune and hematopoietic systems play important roles in prostate cancer (PCa), few studies have comprehensively investigated the combined influence of these systems on PCa risk. ...
Frailty and frailty progression in relation to the risk of benign prostatic hyperplasia/lower urinary tract symptoms among Chinese middle-aged and older men: a prospective cohort study [0.03%]
脆弱性及脆弱性的进展与中国中老年男性良性前列腺增生/下尿路症状风险的关系：前瞻性队列研究
Liangliang Li,Antao Dong,Kun Liu et al.
Liangliang Li et al.
Background: Frailty and benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS) are age-related conditions, but their longitudinal relationship remains unclear. This study investigated associations between fr...
Current treatment for erectile dysfunction: an umbrella review of systematic reviews and meta-analyses [0.03%]
勃起功能障碍的当前治疗方法：系统评价和meta分析的伞式评价
Jian Ma,Jintao Wei,Jinze Li et al.
Jian Ma et al.
Objective: This umbrella review aimed to summarize and provide a general evaluation of the effectiveness of current treatments for erectile dysfunction (ED) and assess the quality of evidence. ...