Stainable hepatic iron in 341 African American adults at coroner/medical examiner autopsy [0.03%]
341名非洲裔美国成人尸体解剖肝铁定性分析
James C Barton,Ronald T Acton,Asia K Richardson et al.
James C Barton et al.
Background: Results of previous autopsy studies indicate that increased hepatic iron stores or hepatic iron overload is common in African Americans dying in hospitals, but there are no reports of hepatic iron content in o...
Tissue eosinophilia: a morphologic marker for assessing stromal invasion in laryngeal squamous neoplasms [0.03%]
喉部鳞状细胞瘤浸润的组织学标志--嗜酸性炎症反应评估的价值
Mahmoud Said,Sam Wiseman,Jun Yang et al.
Mahmoud Said et al.
BACKGROUND: The assessment of tumor invasion of underlying benign stroma in neoplastic squamous proliferation of the larynx may pose a diagnostic challenge, particularly in small biopsy specimens that are frequently tangentially sectioned. ...
Gene deletion of P-Selectin and ICAM-1 does not inhibit neutrophil infiltration into peritoneal cavity following cecal ligation-puncture [0.03%]
基因P-选择素和ICAM-1敲除小鼠在盲肠结扎穿孔术后腹腔中性粒细胞浸润不受影响
Elahé T Crockett,Crystal Remelius,Karen Hess et al.
Elahé T Crockett et al.
BACKGROUND: Neutrophil infiltration is one of the critical cellular components of an inflammatory response during peritonitis. The adhesion molecules, P-selectin and intercellular adhesion molecule (ICAM)-1, mediate neutrophil-endothelial c...
In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR [0.03%]
甲醛固定和PCR过程中错误频繁的跨损伤合成导致的体外突变artifact
Nancy Quach,Myron F Goodman,Darryl Shibata
Nancy Quach
BACKGROUND: Clinical specimens are routinely fixed in 10% buffered formalin and paraffin embedded. Although DNA is commonly extracted from fixed tissues and amplified by PCR, the effects of formalin fixation are relatively unknown. Formalin...
Age-related differences in 1p and 19q deletions in oligodendrogliomas [0.03%]
少突胶质瘤中1号染色体短臂和19号染色体短臂的缺失与年龄相关的差异
Yvonne Myal,Marc R Del Bigio,Roy H Rhodes
Yvonne Myal
BACKGROUND: Recent reports indicate that anaplastic oligodendrogliomas frequently show allelic losses on chromosome arms 1p and 19q, and that these deletions are associated with better chemotherapeutic response and overall patient survival....
The utility of cytokeratins 7 and 20 (CK7/20) immunohistochemistry in the distinction of short-segment Barrett esophagus from gastric intestinal metaplasia: Is it reliable? [0.03%]
CK7/20免疫组化在短段巴雷特食管和胃肠道代谢鉴别中的作用：可靠吗？
Ozlem Kurtkaya-Yapicier,Rasim Gencosmanoglu,Erol Avsar et al.
Ozlem Kurtkaya-Yapicier et al.
BACKGROUND: The purpose of the present correlative immunohistochemical study was to assess the utility of cytokeratin (CK7 and CK20) expression in the diagnosis of short-segment Barrett esophagus, particularly its efficacy in differentiatin...
Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation [0.03%]
正常人体组织中IA类和II类磷脂酰肌醇3-激酶酶的地形学表达与分化有关
Soha Salama El Sheikh,Jan Domin,Prakitpunthu Tomtitchong et al.
Soha Salama El Sheikh et al.
BACKGROUND: Growth factor, cytokine and chemokine-induced activation of PI3K enzymes constitutes the start of a complex signalling cascade, which ultimately mediates cellular activities such as proliferation, differentiation, chemotaxis, su...
Gender dimorphism in differential peripheral blood leukocyte counts in mice using cardiac, tail, foot, and saphenous vein puncture methods [0.03%]
不同采血方法小鼠外周血白细胞性别二态性差异的影响
Diana C Doeing,Jessica L Borowicz,Elahé T Crockett
Diana C Doeing
BACKGROUND: In many animal models that investigate the pathology of various diseases, there is a need to monitor leukocyte counts and differentials. However, various researchers use a range of different techniques in male and female laborat...
Optimization of biotinyl-tyramide-based in situ hybridization for sensitive background-free applications on formalin-fixed, paraffin-embedded tissue specimens [0.03%]
基于生物素酪酰胺的原位杂交法在甲醛固定石蜡包埋组织标本上的优化应用于高敏感背景无忧型实验中
Mark F Evans,Holly A Aliesky,Kumarasen Cooper
Mark F Evans
BACKGROUND: Over the past five years in situ hybridization techniques employing tyramide amplification reagents have been developed and promise the potential detection of low/single-copy nucleic acid sequences. However the increased sensiti...
Membrane androgen binding sites are preferentially expressed in human prostate carcinoma cells [0.03%]
膜雄激素结合位点在人类前列腺癌细胞中优先表达
Efstathios N Stathopoulos,Constantina Dambaki,Marilena Kampa et al.
Efstathios N Stathopoulos et al.
Background: Prostate cancer is one of the most frequent malignancies in males. Nevertheless, to this moment, there is no specific routine diagnostic marker to be used in clinical practice. Recently, the identification of ...