Tissue Harvester with Functional Valve (THFV): Shidham's device for reproducibly higher specimen yield by fine needle aspiration biopsy with easy to perform steps [0.03%]
具有功能阀的组织收获器（THFV）：Shidham设备通过简单易行的步骤实现可重复性的较高细针穿刺活检标本产量
Vinod B Shidham,Ashwini W Pandit,R Nagarjun Rao et al.
Vinod B Shidham et al.
Background: Fine needle aspiration biopsy (FNAB) cytology has been a highly effective methodology for tissue diagnosis and for various ancillary studies including molecular tests. In addition to other benefits, FNAB predo...
Andrew P C McLean-Tooke,Catherine Aldridge,Kimberley Gilmour et al.
Andrew P C McLean-Tooke et al.
Background: Chronic granulomatous disease (CGD) is an inherited disorder of phagocytic cells caused by an inability to generate active microbicidal oxygen species required kill certain types of fungi and bacteria. This le...
Transcriptional profiling of degraded RNA in cryopreserved and fixed tissue samples obtained at autopsy [0.03%]
用于尸检获得的冷冻和固定组织样本中降解RNA的转录谱分析
Andrew C Haller,Deepa Kanakapalli,Rosemarie Walter et al.
Andrew C Haller et al.
Background: Traditional multiplexed gene expression methods require well preserved, intact RNA. Such specimens are difficult to acquire in clinical practice where formalin fixation is the standard procedure for processing...
Concurrent development of testicular seminoma and choriocarcinoma of the superior mediastinum, presented as cervical mass: a case report and implications about pathogenesis of germ-cell tumours [0.03%]
睾丸精原细胞瘤伴发纵隔绒毛膜癌1例及生殖细胞肿瘤发病机制的探讨
Giannis Mountzios,George Pavlakis,Evangelos Terpos et al.
Giannis Mountzios et al.
Background: Synchronous presentation of more than one germ cell tumours of different histology in the same patient is considered to be very rare. In these cases of multiple germ cell tumours, strong theoretical and clinic...
Panagiotis A Konstantinopoulos,Bruce J Dezube,Liron Pantanowitz
Panagiotis A Konstantinopoulos
Background: The spectrum of Kaposi's sarcoma (KS) has been expanded to include pre-KS lesions. Case presentation: We report, for the fi...
Histopathological evaluation of ocular microsporidiosis by different stains [0.03%]
不同染色方法对眼部微孢子虫病的病理组织学评价
Joveeta Joseph,Geeta K Vemuganti,Prashant Garg et al.
Joveeta Joseph et al.
Background: There is limited data on comparing stains in the detection of microsporidia in corneal biopsies. Hence we wanted to evaluate various stains for their ability to detect microsporidia in corneal tissue sections....
Christoph-E Heyde,Sven K Tschoeke,Markus Hellmuth et al.
Christoph-E Heyde et al.
Background: Vertebral fractures resulting from high energy trauma often comprise the risk of posttraumatic degenerative changes in the affected intervertebral discs (IVD). Particularly in conservatively treated patients, ...
Primary histologic diagnosis using automated whole slide imaging: a validation study [0.03%]
应用全视野数字病理图像进行主要组织学诊断的验证性研究
John R Gilbertson,Jonhan Ho,Leslie Anthony et al.
John R Gilbertson et al.
Background: Only prototypes 5 years ago, high-speed, automated whole slide imaging (WSI) systems (also called digital slide systems, virtual microscopes or wide field imagers) are becoming increasingly capable and robust....
Protection of early phase hepatic ischemia-reperfusion injury by cholinergic agonists [0.03%]
胆碱激动剂对肝缺血再灌注早期损伤的保护作用
Elahé T Crockett,James J Galligan,Bruce D Uhal et al.
Elahé T Crockett et al.
Background: Cytokine production is critical in ischemia/reperfusion (IR) injury. Acetylcholine binds to macrophages and inhibits cytokine synthesis, through the cholinergic anti-inflammatory pathway. This study examined t...
Real-time PCR complements immunohistochemistry in the determination of HER-2/neu status in breast cancer [0.03%]
实时定量PCR可作为免疫组化判断乳腺癌HER-2状态的补充方法
Andreea Nistor,Peter H Watson,Norman Pettigrew et al.
Andreea Nistor et al.
Background: The clinical benefit of determining the status of HER-2/neu amplification in breast cancer patients is well accepted. Although immunohistochemistry (IHC) is the most frequently used method to assess the over-e...