Development and evaluation of a virtual microscopy application for automated assessment of Ki-67 expression in breast cancer [0.03%]
乳腺癌Ki-67表达自动化评估的虚拟显微镜应用的研发与评估
Juho Konsti,Mikael Lundin,Heikki Joensuu et al.
Juho Konsti et al.
Background: The aim of the study was to develop a virtual microscopy enabled method for assessment of Ki-67 expression and to study the prognostic value of the automated analysis in a comprehensive series of patients with...
Differential effects of frozen storage on the molecular detection of bacterial taxa that inhabit the nasopharynx [0.03%]
冷冻保存对鼻咽部细菌分子检测的差异影响
Brenda A Kwambana,Nuredin I Mohammed,David Jeffries et al.
Brenda A Kwambana et al.
Background: Frozen storage often precedes metagenomic analysis of biological samples; however, the freezing process can have adverse effects on microbial composition. The effect of freezing on the detection of bacteria in...
Immunohistochemical staining of radixin and moesin in prostatic adenocarcinoma [0.03%]
前列腺腺癌中Radixin和Moesin的免疫组化染色
Tanner L Bartholow,Uma R Chandran,Michael J Becich et al.
Tanner L Bartholow et al.
Background: Some members of the Protein 4.1 superfamily are believed to be involved in cell proliferation and growth, or in the regulation of these processes. While the expression levels of two members of this family, rad...
COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma [0.03%]
低温PCR高分辨率熔解曲线分析技术提高结直肠癌KRAS突变检测的准确性
Colin C Pritchard,Laura Akagi,Poluru L Reddy et al.
Colin C Pritchard et al.
Background: KRAS mutational analysis is the standard of care prior to initiation of treatments targeting the epidermal growth factor receptor (EGFR) in patients with metastatic colorectal cancer. Sensitive methods are req...
Use of the GenoType(R) MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda [0.03%]
基因型MTBDRplus试验用于评估乌干达农村地区结核病患者的药物敏感性菌株状况
Joel Bazira,Benon B Asiimwe,Moses L Joloba et al.
Joel Bazira et al.
Background: Drug resistance levels and patterns among Mycobacterium tuberculosis isolates from newly diagnosed and previously treated tuberculosis patients in Mbarara Uganda were investigated. ...
Accumulation of advanced glycation end (AGEs) products in intensive care patients: an observational, prospective study [0.03%]
重症监护患者的晚期糖基化终产物(AGEs)累积：一项观察性前瞻性研究
Wendela L Greven,Jitty M Smit,Johannes H Rommes et al.
Wendela L Greven et al.
Background: Oxidative stress plays an important role in the course and eventual outcome in a majority of patients admitted to the intensive care unit (ICU). Markers to estimate oxidative stress are not readily available i...
Comparison of haematological parameters determined by the Sysmex KX - 2IN automated haematology analyzer and the manual counts [0.03%]
Sysmex KX-2IN全 自动血液分析仪与手工计数的对比研究
Samuel O Ike,Thomas Nubila,Ernest O Ukaejiofo et al.
Samuel O Ike et al.
Background: This study was designed to determine the correlation between heamatological parameters by Sysmex KX-21N automated hematology analyzer with the manual methods. ...
The combined positive impact of Lean methodology and Ventana Symphony autostainer on histology lab workflow [0.03%]
精益管理方法与Ventana Symphony自动染色机在组织病理学实验室工作流程中的联合积极作用
Lewis A Hassell,Crystal F Glass,Clinton Yip et al.
Lewis A Hassell et al.
Background: Histologic samples all funnel through the H&E microtomy staining area. Here manual processes intersect with semi-automated processes creating a bottleneck. We compare alternate work processes in anatomic patho...
SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma [0.03%]
SNAI1表达与间质表型的关联性研究——对46例口腔鳞癌进行免疫组化分析
Joerg Schwock,Grace Bradley,James C Ho et al.
Joerg Schwock et al.
Background: SNAI1 can initiate epithelial-mesenchymal transition (EMT), leading to loss of epithelial characteristics and, in cancer, to invasion and metastasis. We hypothesized that SNAI1 reactivation occurs in oral squa...
Immunohistochemical and other prognostic factors in B cell non Hodgkin lymphoma patients, Kampala, Uganda [0.03%]
乌干达坎帕拉B细胞非霍奇金淋巴瘤患者的免疫组化和其他预后因素研究
Lynnette K Tumwine,Claudio Agostinelli,Cristina Campidelli et al.
Lynnette K Tumwine et al.
Background: Non Hodgkin lymphomas are the most common lymphomas in Uganda. Recent studies from developed countries have shown differences in survival for the different immunophenotypes. Such studies are lacking in Africa ...