Cell culture model predicts human disease: Altered expression of junction proteins and matrix metalloproteinases in cervical dysplasia [0.03%]
细胞培养模型预测人类疾病：宫颈发育不良时连接蛋白和基质金属蛋白酶表达的变化
Niina Kivi,Mikko Rönty,Jussi Tarkkanen et al.
Niina Kivi et al.
Background: Cervical cancer is necessarily caused by human papillomaviruses, which encode three oncogenes manifesting their functions by interfering with a number of cellular proteins and pathways: the E5, E6, and E7 prot...
Theodor K Mayer,Roberto L Vargas,Ann E Knebel et al.
Theodor K Mayer et al.
Background: Screening and determining the immune status of individuals for hepatitis B is usually done by detecting hepatitis B surface antigen (HBsAg) and hepatitis B surface antigen-specific antibodies (HBsAb). In some ...
Prognostic impact of CD57, CD68, M-CSF, CSF-1R, Ki67 and TGF-beta in soft tissue sarcomas [0.03%]
CD57、CD68、M-CSF、CSF-1R、Ki67和TGF-β在软组织肉瘤中的预后价值
Sveinung W Sorbye,Thomas K Kilvaer,Andrej Valkov et al.
Sveinung W Sorbye et al.
Background: Prognostic markers in curable STS may have the potential to guide therapy after surgical resection. The purpose of this study was to clarify the prognostic impact of the presence of cells and growth factors be...
Evaluation of chemiluminescence, toluidine blue and histopathology for detection of high risk oral precancerous lesions: A cross-sectional study [0.03%]
化学发光、 toluidine蓝和组织病理学检测高危口腔癌前病变的评价：横断面研究
Shweta Ujaoney,Mukta B Motwani,Shirish Degwekar et al.
Shweta Ujaoney et al.
Background: Early detection holds the key to an effective control of cancers in general and of oral cancers in particular. However, screening procedures for oral cancer are not straightforward due to procedural requiremen...
Prognostic impact of peritumoral lymphocyte infiltration in soft tissue sarcomas [0.03%]
软组织肉瘤肿瘤周淋巴细胞浸润的预后价值
Sveinung W Sorbye,Thomas K Kilvaer,Andrej Valkov et al.
Sveinung W Sorbye et al.
Background: The purpose of this study was to clarify the prognostic significance of peritumoral lymphocyte infiltration in the capsule of soft tissue sarcomas (STS). Multiple observations in preclinical and clinical studi...
Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas [0.03%]
人类胶质瘤中LAT1/4F2hc表达与病理分级、增殖和血管生成的关系
Zhen Haining,Nobuyuki Kawai,Keisuke Miyake et al.
Zhen Haining et al.
Background: LAT1/4F2hc heterodimeric complex is a major route for the transport of large neutral essential amino acids through the plasma membrane. Although it has been shown that LAT1/4F2hc is highly expressed in a varie...
Dual color chromogenic in situ hybridization for determination of HER2 status in breast cancer: a large comparative study to current state of the art fluorescence in situ hybridization [0.03%]
乳腺癌HER2状态检测的双色显色原位杂交方法的大样本比较研究：与当前荧光原位杂交技术的状态对比研究
Jens Mollerup,Ulla Henriksen,Sven Müller et al.
Jens Mollerup et al.
Background: Chromogenic in situ hybridization (CISH) is fast becoming a well established technique for easy and sensitive determination of HER2 gene status in breast cancer. However, for the chromogenic method to achieve ...
Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer [0.03%]
结肠癌中胶原三联重复序列含1蛋白和核因子(E2相关因子-3)样分子3的检测
Marco Palma,Lissett Lopez,Margarita García et al.
Marco Palma et al.
Background: Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 (NFE2L3) may be useful biomarker candidates for the diagnosis of colorectal cancer (CRC) since they have shown...
A retrospective analysis of glycol and toxic alcohol ingestion: utility of anion and osmolal gaps [0.03%]
回顾性分析甘油和有毒醇类摄入：阴离子隙和渗透压间隙的临床意义
Matthew D Krasowski,Rebecca M Wilcoxon,Joel Miron
Matthew D Krasowski
Background: Patients ingesting ethylene glycol, isopropanol, methanol, and propylene glycol ('toxic alcohols') often present with non-specific signs and symptoms. Definitive diagnosis of toxic alcohols has traditionally b...
Molecular preservation by extraction and fixation, mPREF: a method for small molecule biomarker analysis and histology on exactly the same tissue [0.03%]
基于提取和固定的分子级保存方法（mPREF）：同一组织中小分子生物标志物分析与组织学研究
Jeffrey R Shuster,Raymond S Lance,Dean A Troyer
Jeffrey R Shuster
Background: Histopathology is the standard method for cancer diagnosis and grading to assess aggressiveness in clinical biopsies. Molecular biomarkers have also been described that are associated with cancer aggressivenes...