Expression of drug targets in primary and matched metastatic renal cell carcinoma tumors [0.03%]
原发性与匹配的肾细胞癌转移瘤中的药物靶点表达
Saadia A Aziz,Joshua A Sznol,Adebowale Adeniran et al.
Saadia A Aziz et al.
Background: Targeted therapies in renal cell carcinoma can have different effects on primary and metastatic tumors. To pave the way for predictive biomarker development, we assessed differences in expression of targets of...
Expression profiling of 21 biomolecules in locally advanced nasopharyngeal carcinomas of Caucasian patients [0.03%]
卡耐基患者局部晚期鼻咽癌的基因表达谱分析21种生物分子
Dimitrios Krikelis,Mattheos Bobos,Georgia Karayannopoulou et al.
Dimitrios Krikelis et al.
Background: Since scarce data exist on the pathogenesis of nasopharyngeal carcinoma in Caucasian patients, we attempted to elucidate the responsible molecular pathways in this patient population. ...
Low Mmp 9 and VEGF levels predict good oncologic outcome in mid and low rectal cancer patients with neoadjuvant chemoradiation [0.03%]
术前放化疗中、低位直肠癌患者低基线MMP-9和VEGF水平预示着较好的肿瘤学转归
Atilla Kurt,Fatih Yanar,Oktar Asoglu et al.
Atilla Kurt et al.
Background: The aim of this study was to evaluate apoptotic (Bcl-2, Bax expression, caspase-3 activity, and cytochrome-c) and angiogenic (MMP-9 levels and VEGF expression) markers in operable rectal cancer patients who we...
S Olatunbosun Banjoko,Falilat A Oseni,Rachel A Togun et al.
S Olatunbosun Banjoko et al.
Background: There had been conflicting reports with levels of markers of iron metabolism in HIV infection. This study was therefore aimed at investigating iron status and its possible mediation of severity of HIV- 1 infec...
Frederick G Behm,Igor M Gavin,Oleksiy Karpenko et al.
Frederick G Behm et al.
Background: Fibromyalgia (FM) is a clinical syndrome characterized by chronic pain and allodynia. The diagnosis of FM has been one of exclusion as a test to confirm the diagnosis is lacking. Recent data highlight the role...
Lack of MMP-9 expression is a marker for poor prognosis in Dukes' B colorectal cancer [0.03%]
DukesB期结直肠癌患者中MMP-9低表达提示预后不良
Selja Koskensalo,Jaana Hagström,Nina Linder et al.
Selja Koskensalo et al.
Background: Matrix metalloproteinases (MMPs) play a role in cancer progression by degrading extracellular matrix and basement membranes, assisting in tumour neovascularization and in supporting immune response in cancer. ...
Factors associated with serum CA19-9 levels among healthy children: a cross-sectional study [0.03%]
健康儿童血清CA19-9水平的相关因素分析：横断面研究
Sayo Kawai,Sueli M Oba-Shinjo,Lucy S Ito et al.
Sayo Kawai et al.
Background: CA19-9 is a tumor marker mainly used for biliary tract, pancreas and colorectum. Since the marker applies usually for adults, the normal range of serum CA19-9 among children has been rarely reported. This is t...
Trop-2 protein overexpression is an independent marker for predicting disease recurrence in endometrioid endometrial carcinoma [0.03%]
Trop-2蛋白过表达是子宫内膜样腺癌复发的独立预后指标
Eliana Bignotti,Laura Zanotti,Stefano Calza et al.
Eliana Bignotti et al.
Background: Endometrial cancer is the most common gynecologic malignancy in developed countries. Trop-2 is a glycoprotein involved in cellular signal transduction and is differentially overexpressed relative to normal tis...
Development of a new method for identification and quantification in cerebrospinal fluid of malignant cells from breast carcinoma leptomeningeal metastasis [0.03%]
脑膜转移乳腺癌脊髓液恶性细胞鉴定和量化的新方法的开发
Emilie Le Rhun,Frédéric Massin,Qian Tu et al.
Emilie Le Rhun et al.
Background: The diagnosis of leptomeningeal metastasis (LM) in patients with solid tumors remains difficult. The usual diagnostic methods of cytomorphological assessment of cerebro-spinal fluid (CSF) and gadolinium enhanc...
A first insight into the genotypic diversity of Mycobacterium tuberculosis from Rwanda [0.03%]
卢旺达结核分枝杆菌基因型多样性初探
James Gafirita,Alaine N Umubyeyi,Benon B Asiimwe
James Gafirita
Background: Mycobacterium tuberculosis complex (MTC) is the causative agent of tuberculosis (TB). Globally, increasing evidence shows that in M. tuberculosis, transmission varies from strain to strain and that different s...