Comparison of automated and manual FISH for evaluation of HER2 gene status on breast carcinoma core biopsies [0.03%]
乳腺癌核心活检HER2基因状态评估的FISH手工操作和自动化操作对比研究
Christian Ohlschlegel,Doris Kradolfer,Margreth Hell et al.
Christian Ohlschlegel et al.
Background: Positive HER2 status identifies breast carcinomas that might respond to trastuzumab treatment. Manual HER2 fluorescent in situ hybridisation (FISH) is the most readily used method to detect HER2 gene amplifica...
Pre-operative hypoalbuminaemia predicts poor overall survival in rectal cancer: a retrospective cohort analysis [0.03%]
术前低白蛋白血症可预测结直肠癌患者总体生存率较低：一项回顾性队列分析
Pramodh C Chandrasinghe,Dileepa S Ediriweera,Sumudu K Kumarage et al.
Pramodh C Chandrasinghe et al.
Background: Serum albumin is a marker of nutrition and inflammation. It has recently emerged as a predictor of outcome after surgery for rectal cancer. Our aim was to evaluate if pre-operative serum albumin would predict ...
Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study [0.03%]
萎缩性胃炎和胃癌患者血清miR-20a-5p、let-7a及miR-320a表达水平及其与血清胃蛋白酶原变化关系的病例对照研究
Qian Xu,Qi-Guan Dong,Li-Ping Sun et al.
Qian Xu et al.
Background: The identification of serial miRNAs targeting the same functional gastric protein could provide new and effective serological biomarkers for the diagnosis of gastric cancer (GC). The aim of this study was to e...
Porntipa Sirivanichsuntorn,Somboon Keelawat,Kittipong Danuthai et al.
Porntipa Sirivanichsuntorn et al.
Background: Mucoepidermoid carcinoma (MEC) can be classified into low-, intermediate-, and high-grade tumors based on its histological features. MEC is mainly composed of three cell types (squamous or epidermoid, mucous a...
Prognostic impact of Skp2, ER and PGR in male and female patients with soft tissue sarcomas [0.03%]
Skp2、ER和PGR在软组织肉瘤男性和女性患者中的预后价值
Sveinung W Sorbye,Thomas K Kilvaer,Andrej Valkov et al.
Sveinung W Sorbye et al.
Background: S-phase kinase-associated protein 2 (Skp2) is a member of mammalian F-box proteins. The purpose of this study is to clarify the prognostic significance of expression of Skp2 related to gender, estrogen recepto...
Morphological distribution of μ chains and cd15 receptors in colorectal polyp and adenocarcinoma specimens [0.03%]
μ链和CD15受体在大肠息肉及腺癌中的形态分布研究
Caterina Defendenti,Fabiola Atzeni,Anna Maria Croce et al.
Caterina Defendenti et al.
Background: We have recently investigated the localisation of immunoglobulin-producing cells (IPCs) in inflamed intestinal tissue samples from patients with inflammatory bowel disease (IBD), and identified two main patter...
Cervical lymph node metastases from thyroid cancer: does thyroglobulin and calcitonin measurement in fine needle aspirates improve the diagnostic value of cytology? [0.03%]
甲状腺癌颈部淋巴结转移：细针穿刺液测定甲状腺球蛋白和降钙素对细胞学诊断价值的提高？
Enke Baldini,Salvatore Sorrenti,Cira Di Gioia et al.
Enke Baldini et al.
Background: Measurement of thyroglobulin (Tg) protein in the washout of the needle used for fine needle aspiration biopsy cytology (FNAB-C) has been shown to increase the sensitivity of FNAB-C in identifying cervical lymp...
Quantification of fractal dimension and Shannon's entropy in histological diagnosis of prostate cancer [0.03%]
前列腺癌组织病理学诊断中的分形维数与香农熵的量化分析
Pedro Francisco Ferraz de Arruda,Márcio Gatti,Fernando Nestor Facio Jr et al.
Pedro Francisco Ferraz de Arruda et al.
Background: Prostate cancer is a serious public health problem that affects quality of life and has a significant mortality rate. The aim of the present study was to quantify the fractal dimension and Shannon's entropy in...
A simple immunohistochemical panel comprising 2 conventional markers, Ki67 and p53, is a powerful tool for predicting patient outcome in luminal-type breast cancer [0.03%]
在乳腺癌 Luminal型中，包含Ki67和p53两个传统标记物的简单免疫组化模型可有效预测患者预后
Takayuki Kobayashi,Keiichi Iwaya,Tomoyuki Moriya et al.
Takayuki Kobayashi et al.
Background: Ki67 is widely used in order to distinguish the "A" and "B" subtypes of luminal-type breast cancer. This study aimed to validate the prognostic value of adding p53 to Ki67 for characterizing luminal-type breas...
13-year-old tuberous sclerosis patient with renal cell carcinoma associated with multiple renal angiomyolipomas developing multifocal micronodular pneumocyte hyperplasia [0.03%]
一名13岁结节硬化症并发肾细胞癌和多发性肾血管肌脂瘤致肺泡上皮增生症患者
Carl Ludwig Behnes,Gunther Schütze,Christoph Engelke et al.
Carl Ludwig Behnes et al.
Background: The autosomal dominant tumor syndrome tuberous sclerosis complex is caused by the mutated TSC1 gene, hamartin, and the TSC2 gene, tuberin. Patients with this complex develop typical cutaneus symptoms such as p...
Case Reports
BMC clinical pathology. 2013 Feb 5:13:4. DOI:10.1186/1472-6890-13-4 2013