Efficient and reproducible identification of mismatch repair deficient colon cancer: validation of the MMR index and comparison with other predictive models [0.03%]
结肠癌错配修复缺陷的高效和可重复识别：MMR指数的验证及其他预测模型的比较
Patrick Joost,Pär-Ola Bendahl,Britta Halvarsson et al.
Patrick Joost et al.
Background: The identification of mismatch-repair (MMR) defective colon cancer is clinically relevant for diagnostic, prognostic and potentially also for treatment predictive purposes. Preselection of tumors for MMR analy...
An observational study on the expression levels of MDM2 and MDMX proteins, and associated effects on P53 in a series of human liposarcomas [0.03%]
MDM2和MDMX蛋白表达水平及其对一组人类脂肪肉瘤中P53的影响的观察性研究
Nader Touqan,Christine P Diggle,Edlo T Verghese et al.
Nader Touqan et al.
Background: Inactivation of wild type P53 by its main cellular inhibitors (MDM2 and MDMX) is a well recognised feature of tumour formation in liposarcomas. MDM2 over-expression has been detected in approximately 80% of li...
The relationship between lymphovascular invasion and angiogenesis, hormone receptors, cell proliferation and survival in patients with primary operable invasive ductal breast cancer [0.03%]
原发性可手术侵袭性导管乳腺癌患者中淋巴管侵犯与血管生成、激素受体、细胞增殖和存活之间的关系
Zahra Ma Mohammed,Donald C McMillan,Joanne Edwards et al.
Zahra Ma Mohammed et al.
Background: Several well-established tumour prognostic factors are used to guide the clinical management of patients with breast cancer. Lymphovascular invasion and angiogenesis have also been reported to have some promis...
Metabolic markers GAPDH, PKM2, ATP5B and BEC-index in advanced serous ovarian cancer [0.03%]
代谢标志GAPDH、PKM2、ATP5B和BECI指数在晚期浆液性卵巢癌中的作用
Elisabet Hjerpe,Suzanne Egyhazi Brage,Joseph Carlson et al.
Elisabet Hjerpe et al.
Background: A deregulated energy metabolism is a hallmark of malignant disease that offers possible future targets for treatment. We investigated the prognostic value of the glycolytic enzymes glyceraldehyde 3-phosphate d...
A mill based instrument and software system for dissecting slide-mounted tissue that provides digital guidance and documentation [0.03%]
一种基于磨床的仪器和软件系统，用于解剖载玻片上的组织，提供数字指导和记录
Nils Adey,Dale Emery,Derek Bosh et al.
Nils Adey et al.
Background: Dissection of specific Areas Of Interest (AOIs) of slide-mounted tumor samples is often used to enrich for cancer cells in order to generate better signal to noise ratios in subsequent biochemical characteriza...
Women with familial risk for breast cancer have an increased frequency of aldehyde dehydrogenase expressing cells in breast ductules [0.03%]
有乳腺癌家族史的女性其乳腺导管上皮中乙醛脱氢酶阳性细胞的比例较高
Björn L Isfoss,Bo Holmqvist,Helena Jernström et al.
Björn L Isfoss et al.
Background: Knowledge is limited regarding the association between stem cells in histologically benign breast tissue and risk factors for breast cancer, and hence we addressed this issue in the present study. Recently, we...
Investigation of factors potentially influencing calcitonin levels in the screening and follow-up for medullary thyroid carcinoma: a cautionary note [0.03%]
髓母细胞甲状腺癌筛查和随访中可能影响降钙素水平的因素调查———致病因素注意说明注释
Christoph Guesgen,Arnulf Willms,Axel Zwad et al.
Christoph Guesgen et al.
Background: The malignant transformation of thyroid C cells is associated with an increase in human calcitonin (hCT), which can thus be helpful in the early diagnosis of medullary thyroid carcinoma (MTC). For this reason,...
Segmental arterial mediolysis of left gastric artery: a case report and review of pathology [0.03%]
胃左动脉节段性中层病理性离解症一例并文献复习
Azra Tabassum,Sanaz Sasani,Adeeb J Majid et al.
Azra Tabassum et al.
Background: Segmental arterial mediolysis (SAM) is a rare non inflammatory vascular disease that can present with massive haemorrhage, which may lead to death without prompt surgical intervention. ...
Comparison of metabolic ratios of urinary estrogens between benign and malignant thyroid tumors in postmenopausal women [0.03%]
绝经后妇女甲状腺良恶性肿瘤患者尿雌激素代谢比值的比较研究
Ju-Yeon Moon,Eun Jig Lee,Woong Youn Chung et al.
Ju-Yeon Moon et al.
Background: Estrogen metabolism may be associated with the pathophysiological development of papillary thyroid carcinoma (PTC). Methods: ...
Julia Alcaide,Rafael Funez,Antonio Rueda et al.
Julia Alcaide et al.
Background: Alterations to apoptosis are a common occurrence in human tumours. The aim of our study was to determine the influence of apoptotic variations on the carcinogenesis and prognosis of colorectal carcinomas (CRCs...