Patrizia D&#x;Amelio,Ilaria Roato,Marco Oderda et al.
Patrizia D&#x;Amelio et al.
Background: Dickoppf-1 (DKK-1) is a negative regulator of bone formation with tumorigenic potential. The up-regulation of DKK-1 is an early event in prostate cancer (PCa) development, thus we investigated its role as a ma...
Expression of histone deacetylases 1, 2 and 3 in urothelial bladder cancer [0.03%]
尿路上皮膀胱癌中组蛋白去乙酰化酶1、2和3的表达
Cédric Poyet,Bastian Jentsch,Thomas Hermanns et al.
Cédric Poyet et al.
Background: Histone deacetylases (HDACs) are known to be associated with an overexpression in different types of cancer such as colon and prostate cancer. In this study we aimed to evaluate the protein expression of class...
High tumor cell expression of microRNA-21 in node positive non-small cell lung cancer predicts a favorable clinical outcome [0.03%]
淋巴结阳性非小细胞肺癌中高水平的肿瘤微RNA-21预示较好的临床结局
Helge Stenvold,Tom Donnem,Sigve Andersen et al.
Helge Stenvold et al.
Background: MicroRNA (miR)-21 has been revealed as an oncogene in cancer development, and is one of the miRNAs closely connected to angiogenesis. We aimed to explore the impact of miR-21 expression in both tumor and strom...
Ephrin (Eph) receptor A1, A4, A5 and A7 expression in human non-small cell lung carcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients' survival [0.03%]
人非小细胞肺癌中EFN受体A1、A4、A5和A7的表达及其与临床病理参数、肿瘤增殖能力及患者生存率的关系研究
Constantinos Giaginis,Nikolaos Tsoukalas,Evangelos Bournakis et al.
Constantinos Giaginis et al.
Background: Ephrin (Eph) receptors are frequently overexpressed in a wide variety of human malignant tumors, being associated with tumor growth, invasion, metastasis and angiogenesis. The present study aimed to evaluate t...
Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling [0.03%]
基于MALDI质谱的胆道癌潜在血清肽类生物标志物识别研究
Neomal S Sandanayake,Stephane Camuzeaux,John Sinclair et al.
Neomal S Sandanayake et al.
Background: The aim of this discovery study was the identification of peptide serum biomarkers for detecting biliary tract cancer (BTC) using samples from healthy volunteers and benign cases of biliary disease as control ...
Should prophylactic thrombolysis be routine in clinical practice? Evidence from an autopsy case of septicemia [0.03%]
尸检病例探讨脓毒症的预防性溶栓是否应成为常规临床实践？
Kunihiro Inai,Sakon Noriki,Hiromichi Iwasaki
Kunihiro Inai
Background: Central venous catheters provide easy access for intravenous infusion and nutrition, but they can bring about complications such as catheter-related infections. Infected central venous catheters often cause no...
Case Reports
BMC clinical pathology. 2014 Jan 30;14(1):6. DOI:10.1186/1472-6890-14-6 2014
The VEGF- and PDGF-family of angiogenic markers have prognostic impact in soft tissue sarcomas arising in the extremities and trunk [0.03%]
VEGF和PDGF族血管生成标志物对肢体和躯干起源于软组织肉瘤的预后影响
Thomas K Kilvaer,Eivind Smeland,Andrej Valkov et al.
Thomas K Kilvaer et al.
Background: Soft-tissue sarcomas are rare malignant tumors of mesenchymal lineage that can arise in any part of the body. Prognosis, and hence also treatment may vary according to histologic subtype and localization. Angi...
First North American case of Hemoglobin Shepherds Bush (β 74[E18] Gly → Asp) in a central Pennsylvania family [0.03%]
Shepherd's Bush血红蛋白（β链74[G18]甘氨酸→天冬氨酸）北美首例：宾夕法尼亚州中心地区一家族病例报告
Scott L Paradise,Lauren Estep,Jordan Olson et al.
Scott L Paradise et al.
Background: Hemoglobin Shepherds Bush (Human Genome Variation Society name: HBB:c.224G > A) is an unstable hemoglobin variant resulting from a β 74 GGC to GAC mutation (Gly to Asp) that manifests clinically as hemolytic ...
Case Reports
BMC clinical pathology. 2014 Jan 15;14(1):4. DOI:10.1186/1472-6890-14-4 2014
Increased fatty acid synthase expression in prostate biopsy cores predicts higher Gleason score in radical prostatectomy specimen [0.03%]
活检标本中脂肪酸合成酶表达增加预示根治性前列腺切除术标本的Gleason评分增高
Shinsuke Hamada,Akio Horiguchi,Kenji Kuroda et al.
Shinsuke Hamada et al.
Background: Fatty acid synthase (FAS) is highly expressed in various types of cancer, and elevated expression of FAS has been suggested to be a predictor of tumor aggressiveness and poor prognosis. We examined whether FAS...
Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells [0.03%]
转录因子NFI家族成员调节人乳腺癌细胞中的磺基转移酶1A1（SULT1A1）基因表达
Aiwei Yao-Borengasser,Lora J Rogers,Vineetha K Edavana et al.
Aiwei Yao-Borengasser et al.
Background: Sulfotransferase 1A1 (SULT1A1) gene expression is tissue specific, with little to no expression in normal breast epithelia. Expression in breast tumors has been documented, but the transcriptional regulation o...