A simple and cost-effective method of DNA extraction from small formalin-fixed paraffin-embedded tissue for molecular oncologic testing [0.03%]
一种从小型福尔马林固定石蜡包埋组织中提取DNA进行分子肿瘤检测的简单且低成本的方法
Anthony N Snow,Aaron A Stence,Jonathan A Pruessner et al.
Anthony N Snow et al.
Background: Extraction of DNA from formalin-fixed, paraffin-embedded (FFPE) tissue is a critical step in molecular oncologic testing. As molecular oncology testing becomes more important for prognostic and therapeutic dec...
Clinical chemistry profiles in injection heroin users from Coastal Region, Kenya [0.03%]
肯尼亚沿海地区注射海洛因使用者的临床化学特征分析
Tom Were,Jesca O Wesongah,Elly Munde et al.
Tom Were et al.
Background: Although the co-burden of injection drug use and HIV is increasing in Africa, little is known about the laboratory markers of injection drug use and anti-retroviral treatment (ART) in Kenyan injection drug use...
Evaluation and clinical significance of the stomach age model for evaluating aging of the stomach-a multicenter study in China [0.03%]
胃龄模型评估及其临床意义的多中心研究
Qin-Yan Gao,Zhen-Hua Wang,Yun Cui et al.
Qin-Yan Gao et al.
Background: A higher prevalence of chronic atrophic gastritis (CAG) occurs in younger adults in Asia. We used Stomach Age to examine the different mechanisms of CAG between younger adults and elderly individuals, and esta...
Comparability of HbA1c and lipids measured with dried blood spot versus venous samples: a systematic review and meta-analysis [0.03%]
基于干燥血斑和静脉采血管检测糖化血红蛋白及血脂的可比性：系统综述和meta分析
Eshan T Affan,Devarsetty Praveen,Clara K Chow et al.
Eshan T Affan et al.
Background: Levels of haemoglobin A1c (HbA1c) and blood lipids are important determinants of risk in patients with diabetes. Standard analysis methods based upon venous blood samples can be logistically challenging in res...
Dermal wound transcriptomic responses to Infection with Pseudomonas aeruginosa versus Klebsiella pneumoniae in a rabbit ear wound model [0.03%]
兔耳伤口模型中铜绿假单胞菌和肺炎克雷伯氏菌感染引起的真皮伤口转录组响应差异分析
Kai P Leung,Peter D&#x;Arpa,Akhil K Seth et al.
Kai P Leung et al.
Background: Bacterial infections of wounds impair healing and worsen scarring. We hypothesized that transcriptome analysis of wounds infected with Klebsiella pneumoniae (K.p.) or Pseudomonas aeruginosa (P.a.) would indica...
Serum TFF3 may be a pharamcodynamic marker of responses to chemotherapy in gastrointestinal cancers [0.03%]
血清TFF3可能是胃肠道癌症化疗反应的药效学标志物
Li Xiao,Yun-Peng Liu,Chuan-Xing Xiao et al.
Li Xiao et al.
Background: As a secreted protein, serum trefoil factor 3 (TFF3) has been reported to be a biomarker of several malignancies. We further investigated whether TFF3 can be applied as a biomarker for and predictor of respons...
Fabrice Mac-Way,Andrea Trombetti,Christian Noel et al.
Fabrice Mac-Way et al.
Background: Bisphosphonates have been widely used for treatment of high bone resorption states. It lowers bone turnover by inhibiting osteoclasts bone resorption with various mechanisms of actions: inhibition of osteoclas...
Case Reports
BMC clinical pathology. 2014 Jul 8:14:31. DOI:10.1186/1472-6890-14-31 2014
alphaB-crystallin is a marker of aggressive breast cancer behavior but does not independently predict for patient outcome: a combined analysis of two randomized studies [0.03%]
角蛋白αB-晶体蛋白是侵袭性乳腺癌的标志物但并不独立预示患者的结果：对两项随机研究的联合分析
Triantafyllia Koletsa,Flora Stavridi,Mattheos Bobos et al.
Triantafyllia Koletsa et al.
Background: alphaB-crystallin is a small heat shock protein that has recently been characterized as an oncoprotein correlating with the basal core phenotype and with negative prognostic factors in breast carcinomas. The p...
Autologous anti-SOX2 antibody responses reflect intensity but not frequency of antigen expression in small cell lung cancer [0.03%]
自体抗SOX2抗体反应反映了小细胞肺癌中抗原表达的强度而非频率
Sukru Atakan,Hulya Bayiz,Serpil Sak et al.
Sukru Atakan et al.
Background: Anti-SOX2 antibody responses are observed in about 10 to 20% of small cell lung cancer (SCLC) patients. The aim of this study was to determine whether such responses reflect a particular pattern of SOX2 protei...
Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer [0.03%]
胸苷磷酸化酶的表达与转移性结直肠癌患者的无进展生存期相关
Elinor Bexe Lindskog,Kristoffer Derwinger,Bengt Gustavsson et al.
Elinor Bexe Lindskog et al.
Background: 5-Fluorouracil (5-FU) is the cornerstone of chemotherapeutic treatment for patients with colorectal cancer. The enzyme thymidine phosphorylase (TP) catalyzes the conversion of 5-FU to its active metabolite, 5-...