Magnus Hallin,Omar L Qassid,Robin L Jones et al.
Magnus Hallin et al.
Medulloblastoma cancer stem cells: molecular signatures and therapeutic targets [0.03%]
髓母细胞瘤癌症干细胞：分子特征和治疗靶点
Hisham F Bahmad,Robert J Poppiti
Hisham F Bahmad
Medulloblastoma (MB) is the most common malignant primary intracranial neoplasm diagnosed in childhood. Although numerous efforts have been made during the past few years to exploit novel targeted therapies for this aggressive neoplasm, the...
Integrated characterisation of cancer genes identifies key molecular biomarkers in stomach adenocarcinoma [0.03%]
综合特征谱分析鉴定出胃腺癌关键分子标志物
Haifeng Wang,Liyijing Shen,Yaoqing Li et al.
Haifeng Wang et al.
Aims: Gastric cancer is one of the leading causes for cancer mortality. Recent studies have defined the landscape of genomic alterations of gastric cancer and their association with clinical outcomes. However, the pathoge...
Prognostic value of perineural invasion in prostate needle biopsies: a population-based study of patients treated by radical prostatectomy [0.03%]
前列腺针吸活检中穿神经侵犯的预后价值：一项根治性前列腺切除术患者的队列研究
Peter Ström,Tobias Nordström,Brett Delahunt et al.
Peter Ström et al.
Aims: Despite being one of the major pathways for the spread of malignant tumours, perineural invasion (PNI) has not conclusively been shown to have an independent prognostic value for prostate cancer. Prostatic biopsy co...
De novo haemoglobin sabine masquerading as double heterozygosity for HbQ-India and β-thalassemia trait: first report from South Asia [0.03%]
新发的血红蛋白萨宾病伪装成印度HbQ和β-地中海贫血双重杂合性：南亚首例报告
Manu Jamwal,Jasbir Kaur,Sanjeev Chhabra et al.
Manu Jamwal et al.
Flagging performance of Sysmex XN-10 haematology analyser for malaria detection [0.03%]
Sysmex XN-10血液分析仪在疟疾检测中的表现警告信号性能评估
Cécile Dumas,Pauline Tirard-Collet,Fanélie Mestrallet et al.
Cécile Dumas et al.
Aim: The aim was to assess the flagging performance of Sysmex XN-10 haematology analyser for malaria detection through the parasitic red blood cell ('pRBC') alarm. ...
Norris Hollie,Saja Asakrah
Norris Hollie
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) occurs in approximately 9% of non-Hodgkin B cell lymphoma. However, it occurs only rarely within the colon. The presentation is often asymptomatic, and c...
Combined use of gap-PCR and next-generation sequencing improves thalassaemia carrier screening among premarital adults in China [0.03%]
婚前成人地中海贫血筛查中联合使用gap-PCR和新一代测序技术的优势
Jianghong Zhao,Jia Li,Qiaohong Lai et al.
Jianghong Zhao et al.
Aims: Thalassaemia is one of the most common genetics disorders in the world, especially in southern China. The aim of the present study was to investigate the feasibility of combining the gap-PCR and next-generation sequ...
Gene of the month: GLI-1 [0.03%]
基因解读：GLI-1
Runjan Chetty
Runjan Chetty
The Glioma-associated homologue-1 (GLI-1) gene was first discovered to be amplified in glioblastoma multiforme. It encodes for a zinc-finger transcription factor in the Kruppel family of proteins and is important in the sonic hedgehog signa...
An exceptional metaplastic lobular breast carcinoma diagnosed through exome sequencing [0.03%]
通过外显子组测序诊断的特殊形态的乳腺小叶癌
Anthony Bergeron,Isabelle Desmoulins,Francoise Beltjens et al.
Anthony Bergeron et al.
Metaplastic breast carcinoma is a rare subtype of breast cancer. This subtype is mostly found in association with poorly differentiated ductal breast carcinomas and rarely with other breast carcinoma types. We report the case of a 69-year-o...