Gene of the month: the 2019-nCoV/SARS-CoV-2 novel coronavirus spike protein [0.03%]
基因解读：2019-nCoV/SARS-CoV-2新型冠状病毒S刺突糖蛋白基因
Tahir S Pillay
Tahir S Pillay
The year 2020 has seen a major and sustained outbreak of a novel betacoronavirus (severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2) infection that causes fever, severe respiratory illness and pneumonia, a disease called COVID-19...
Camilla Paulla de Souza,Beatriz Alves,Jaques Waisberg et al.
Camilla Paulla de Souza et al.
Aims: To determine the expression of the cyclooxygenase-2 (COX-2) gene in patients with breast cancer attended at the Centro Universitário Saúde ABC/Faculdade de Medicina do ABC (CUS-ABC/FMABC) outpatient clinic. Breast...
Clinicopathological and molecular features of hereditary leiomyomatosis and renal cell cancer-associated renal cell carcinomas [0.03%]
遗传性平滑肌瘤病和肾细胞癌相关的肾细胞癌的临床病理和分子特征
Mitsuko Furuya,Yasuhiro Iribe,Yoji Nagashima et al.
Mitsuko Furuya et al.
Aims: Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an autosomal dominant disorder caused by germline mutations in fumarate hydratase (FH). Affected families have an increased risk of renal cell carcinoma (RC...
SARS-CoV-2 detection in formalin-fixed paraffin-embedded tissue specimens from surgical resection of tongue squamous cell carcinoma [0.03%]
舌鳞状细胞癌手术切除标本石蜡块中SARS-CoV-2的检测
Elena Guerini-Rocco,Sergio Vincenzo Taormina,Davide Vacirca et al.
Elena Guerini-Rocco et al.
In the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, pathologists can be exposed to infection handling surgical specimens. Guidelines related to safety procedures in the laboratory have been released. However, there...
Implementing a structured digital-based online pathology curriculum for trainees at the time of COVID-19 [0.03%]
新冠肺炎疫情期间基于数字的在线病理学培训项目的设计与实施
Simon F Roy,Matthew J Cecchini
Simon F Roy
L1 cell adhesion molecule (L1CAM) in stage IB cervical cancer: distinct expression in squamous cell carcinomas and adenocarcinomas [0.03%]
宫颈癌IB期的L1细胞粘附分子(L1CAM)：鳞状细胞癌和腺癌中的不同表达
Joao Paulo Mancusi de Carvalho,Rafael C Salim,Filomena Marino Carvalho et al.
Joao Paulo Mancusi de Carvalho et al.
Aims: L1 cell adhesion molecule (L1CAM) has been shown to be correlated with tumour progression, attributed to its possible association with epithelial-mesenchymal transition (EMT), characterised by the expression of vime...
Prodipto Pal,Runjan Chetty
Prodipto Pal
Sclerosing pneumocytoma (SP) is a rare benign low-grade tumour of the lung, and typically presents as single discrete coin lesions on imaging. Multiple SP is an exceedingly rare entity and thus reported sparingly. We review the literature o...
Perineural invasion predicts for locoregional failure in patients with oesophageal adenocarcinoma treated with neoadjuvant chemoradiotherapy [0.03%]
术前放化疗治疗食管腺癌患者中瘤周神经侵犯预示局部区域复发风险升高
Ankur K Patel,Xueliang Pan,Diana M Vila et al.
Ankur K Patel et al.
Aim: The prognostic significance of perineural invasion (PNI) in oesophageal adenocarcinoma (EAC) is unclear. We examined the association of PNI with clinical outcomes in patients treated with neoadjuvant chemoradiotherap...
SMARCA family of genes [0.03%]
SMARCA基因家族
Runjan Chetty,Stefano Serra
Runjan Chetty
The SMARCA subgroup of genes belong to the SWI1/SNF1 family that are responsible chromatin remodelling and repair. Inactivating mutations in the main SMARCA genes A2 and A4 lead to loss of expression of their respective proteins within the ...
Cytology in the time of coronavirus disease (COVID-19): an Italian perspective [0.03%]
新型冠状病毒肺炎(COVID-19)时期细胞病理学的意大利观点
Elena Vigliar,Antonino Iaccarino,Dario Bruzzese et al.
Elena Vigliar et al.
Introduction: The coronavirus disease 2019 (COVID-19) is changing the way we practice pathology, including fine needle aspiration (FNA) diagnostics. Although recommendations have been issued to prioritise patients at high...
Comparative Study
Journal of clinical pathology. 2021 Apr;74(4):261-263. DOI:10.1136/jclinpath-2020-206614 2021