Fibronodular hepatocellular carcinoma-a new variant of liver cancer: clinical, pathological and radiological correlation [0.03%]
纤维结节型肝细胞癌——一种新型的肝癌：临床、病理与影像学相关性研究
Jonathan Tefera,Margarita Revzin,Julius Chapiro et al.
Jonathan Tefera et al.
Aims: To establish and define a new, not previously reported hepatocellular carcinoma (HCC) variant, termed fibronodular HCC (FN-HCC). Methods: ...
Determination of cerebrospinal fluid adenosine deaminase activity cut-off for the diagnosis of tuberculous meningitis in Hong Kong [0.03%]
测定脑脊液腺苷脱氨酶活性诊断香港地区结核性脑膜炎的临界值
Toby Chun Hei Chan,Sammy Pak Lam Chen,Chloe Miu Mak et al.
Toby Chun Hei Chan et al.
Aims: Tuberculous meningitis (TBM) is a severe infection which may lead to serious complication and mortality. Prompt diagnosis and treatment are essential. There is a need for a simple and fast laboratory test to differe...
Łukasz Pawliński,Ewa Tobór,Maciej Suski et al.
Łukasz Pawliński et al.
Aims: The research work was conducted to find new biomarkers and potential drug targets in Gaucher disease type 1 (GDt1) by analysing the serum proteins. ...
Observational Study
Journal of clinical pathology. 2021 Jan;74(1):25-29. DOI:10.1136/jclinpath-2020-206580 2021
Cryptosporidium spp surveillance and epidemiology in Ireland: a longitudinal cohort study employing duplex real-time PCR based speciation of clinical cases [0.03%]
利用基于临床病例的双联实时PCR鉴定技术在爱尔兰开展隐孢子虫的监测及流行病学研究：一项纵向队列研究
Jennifer K O&#x;Leary,Liam Blake,Dan Corcoran et al.
Jennifer K O&#x;Leary et al.
Cryptosporidium is a leading cause of gastroenteritis (cryptosporidiosis), with significant morbidity and mortality worldwide. Irish cryptosporidiosis incidence rates are consistently the highest reported in Europe. A retrospective, longitu...
High methionyl-tRNA synthetase expression predicts poor prognosis in patients with breast cancer [0.03%]
甲硫氨酰-tRNA合成酶表达增高预示乳腺癌患者预后不良
Qin Jin,Gang Liu,Biao Wang et al.
Qin Jin et al.
Aims: Methionyl-tRNA synthetase (MARS) is known to play a critical role in initiating translation and protection against cellular damages in vivo. The aim of this study was to clarify the role of MARS in breast cancer (BC...
Clinical relevance of the in situ assay for HBV DNA: a cross-sectional study in patients with chronic hepatitis B [0.03%]
慢性乙型肝炎患者中HBV DNA原位检测的临床意义：横断面研究
Danping Liu,Tong Xu,Bisheng Shi et al.
Danping Liu et al.
Aims: The visualisation of HBV DNA in liver sections of patients with chronic hepatitis B (CHB) in our previous report uncovered a mosaic distribution of viral antigens and nucleic acids. Here we aim to further explore th...
Marietjie Venter,Karin Richter
Marietjie Venter
Countries globally are affected by the COVID-19 pandemic, with nearly two million cases and 120 000 deaths occurring within 4 months of the discovery of the severe acute respiratory syndrome coronavirus-2 in December 2019 in China. Accurate...
Gene of the month: APOL1 [0.03%]
基因解读：APOL1基因
Shanel Raghubeer,Tahir S Pillay,Tandi Edith Matsha
Shanel Raghubeer
Apolipoprotein L1 (APOL1) is a protein encoded by the APOL1 gene, found only in humans and several primates. Two variants encoding two different isoforms exist for APOL1, namely G1 and G2. These variants confer increased protection against ...
Non-fusion mutations in endometrial stromal sarcomas: what is the potential impact on tumourigenesis through cell cycle dysregulation? [0.03%]
非融合型子宫内膜间质肉瘤的突变及其通过细胞周期失调导致肿瘤发生的潜在影响？
Snehal B Patel,Colin McCormack,Jennelle C Hodge
Snehal B Patel
Targeted next-generation sequencing using the 50-gene Ion AmpliSeq Cancer Hotspot Panel v2 identified two significant point mutations in endometrial stromal sarcomas (ESS). Case 1 is a uterine mass from a quadragenarian woman with a karyoty...
Next-generation sequencing and histological response assessment in peritoneal metastasis from pancreatic cancer treated with PIPAC [0.03%]
下一代测序和PIPAC治疗胰腺癌腹膜转移的组织学反应评估
Malene Nielsen,Martin Graversen,Signe Bremholm Ellebæk et al.
Malene Nielsen et al.
Background: Peritoneal metastasis from pancreatic cancer (PM-PC) may be treated with repeated pressurised intraperitoneal aerosol chemotherapy (PIPAC). Utility of next-generation sequencing (NGS) to detect cancer-related ...