Kohei Fujikura,Daisuke Yamashita,Makoto Yoshida et al.
Kohei Fujikura et al.
Aims: To characterise the karyotypic abnormalities and heterogeneities in intravascular lymphoma (IVL). Methods: G-banded karyotyping w...
Irene Gullo,Ana Marques,Regina Pinto et al.
Irene Gullo et al.
The determination of molecular aberrations within tumours is important for diagnostic, prognostic and predictive purposes. Pathologists play a critical role in the workflow of molecular diagnostics, by assuring accurate pathological diagnos...
Immunoinformatic approach to assess SARS-CoV-2 protein S epitopes recognised by the most frequent MHC-I alleles in the Brazilian population [0.03%]
利用免疫信息学方法评估SARS-CoV-2蛋白S表位被巴西人群中常见的MHC-I等位基因所识别的情况
Ronald Rodrigues de Moura,Almerinda Agrelli,Carlos André Santos-Silva et al.
Ronald Rodrigues de Moura et al.
Aims: Brazil is nowadays one of the epicentres of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and new therapies are needed to face it. In the context of specific immune response against the v...
Molecules in pathogenesis: angiotensin converting enzyme 2 (ACE2) [0.03%]
分子在病理生理中的作用：血管紧张素转换酶2(ACE2)
Owen Wiese,Annalise E Zemlin,Tahir S Pillay
Owen Wiese
The renin-angiotensin system is mainly associated with the regulation of blood pressure, but recently many other functions of this system have been described. ACE2, an 805-amino acid monocarboxypeptidase type I transmembrane glycoprotein, w...
Stemness in high-grade serous carcinoma of tubo-ovarian origin causes multiple immunohistochemical pitfalls: a case report [0.03%]
来自输卵管卵巢的高级别浆液性癌中的干细胞样特性会引起多种免疫组化陷阱：一个病例报告
Mieke R Van Bockstal,David Augusto
Mieke R Van Bockstal
Non-neoplastic colorectal disease biopsies: evaluation and differential diagnosis [0.03%]
非肿瘤性结肠疾病活检标本的评估及鉴别诊断
Michelle Moore,Roger M Feakins,Gregory Y Lauwers
Michelle Moore
A wide variety of non-neoplastic conditions may be encountered on colorectal biopsy encompassing idiopathic, infectious, vascular and immune-mediated aetiologies. Although interpretation of such biopsies may be challenging, appreciation of ...
Predictive molecular pathology in the time of coronavirus disease (COVID-19) in Europe [0.03%]
欧洲新型冠状病毒疾病(COVID-19)时期的预测分子病理学
Umberto Malapelle,Pasquale Pisapia,Antonino Iaccarino et al.
Umberto Malapelle et al.
Aims: Lung cancer predictive biomarker testing is essential to select advanced-stage patients for targeted treatments and should be carried out without delays even during health emergencies, such as the coronavirus (COVID...
Digital pathology and COVID-19 and future crises: pathologists can safely diagnose cases from home using a consumer monitor and a mini PC [0.03%]
数字病理学和COVID-19以及未来危机：病理学家可以使用消费级显示器和迷你PC在家安全地进行诊断工作
Alessia Cimadamore,Antonio Lopez-Beltran,Marina Scarpelli et al.
Alessia Cimadamore et al.
Gene of the month: IDH1 [0.03%]
本月基因：IDH1基因
Cassandra Bruce-Brand,Dhirendra Govender
Cassandra Bruce-Brand
Isocitrate dehydrogenase 1 (IDH1) encodes a protein which catalyses the oxidative decarboxylation of isocitrate to α-ketoglutarate. Mutant IDH1 favours the production of 2-hydroxyglutarate, an oncometabolite with multiple downstream effect...
Hanna Ferløv Schwensen,Line Kristine Borreschmidt,Merete Storgaard et al.
Hanna Ferløv Schwensen et al.
There is growing evidence of histopathological changes in autopsied individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, data on histopathological changes in autopsied patients with eradicated COV...