Patterns of HER2 expression and genomic correlates in lung cancer, with a focus on preanalytical variables impacting immunohistochemical staining results [0.03%]
肺癌中HER2表达和基因组相关性的模式，重点关注影响免疫组织化学染色结果的前分析变量
Cristiana M Pineda,Lauren O&#x;Loughlin,Heather L Benjamin et al.
Cristiana M Pineda et al.
Aims: Fam-trastuzumab deruxtecan-nxki (T-DXd) was recently approved for advanced stage or metastatic solid tumours with human epidermal growth factor receptor 2 (HER2) immunohistochemical (IHC) 3+ staining. Data on HER2 I...
Re-evaluating the relevance of extensive intraductal component (EIC) in modern breast cancer management [0.03%]
在现代乳腺癌管理中重新评估广泛的导管内成分(EIC)的相关性
Seyed Reza Taha,Fouad Boulos
Seyed Reza Taha
The concept of extensive intraductal component (EIC), currently defined by the presence of a prominent ductal carcinoma in situ (DCIS) component within an invasive tumor and extending beyond its margins, was introduced in the 1980s as a pre...
Rachel Nelan,Martina Mijuskovic,Martina Hughes et al.
Rachel Nelan et al.
Aims: Whole-genome sequencing (WGS) is beginning to be applied to cancer samples in the clinical setting. This ideally requires high-quality, minimally degraded DNA of high tumour cell content, while retaining sufficient ...
If you provide them, they will come: an observational study of online pathology report access by patients at a large, academic, tertiary care hospital in Canada [0.03%]
你会提供，他们就会来：加拿大一家大型学术三级护理医院的观察研究表明患者对在线病理报告的访问
Jacob Ranot,Pedram Noghani,Deanna Rothwell et al.
Jacob Ranot et al.
Aims: Patients of The Ottawa Hospital (TOH) are given immediate access to their pathology reports via an online patient portal. The purpose of this study was to determine how often patients accessed their reports, the soc...
The fifth edition of the WHO classification of mature T cell, NK cell and stroma-derived neoplasms [0.03%]
世卫组织关于成熟T细胞、NK细胞和基质来源肿瘤分类的第五版
Ayoma D Attygalle,Kennosuke Karube,Yoon Kyung Jeon et al.
Ayoma D Attygalle et al.
The fifth edition of the WHO Classification of Haematolymphoid Tumors (WHO-HAEM5) introduces significant advancements in the understanding and diagnosis of mature T cell and NK cell, and stroma-derived neoplasms, and incorporates molecular ...
Diagnostic dilemmas in idiopathic multicentric Castlemans disease idiopathic plasmacytic lymphadenopathy (IPL) type and IgG4-related lymphadenopathy: challenges in recognition and distinction, especially in western pathology [0.03%]
诊断困境于特发性多中心Castleman病(IPL)类型和IgG4相关淋巴结病：识别和区分的挑战，特别是在西方病理学中
Vikram Deshpande,Judith Ferry
Vikram Deshpande
Claudin18.2 expression in gallbladder cancer correlates with immune activation and a favourable prognosis [0.03%]
胆囊癌中 Claudin18.2 的表达与免疫激活和有利的预后有关
Shu-Juan Ni,Xin Wang,Lin Yuan et al.
Shu-Juan Ni et al.
Aims: Gallbladder carcinoma (GBC) is frequently diagnosed and treated in advanced stages and has a poor prognosis. Recent studies have identified claudin18.2 (CLDN18.2) as a promising target in digestive system cancer. In...
New evidence for fibrocartilaginous dysplasia representing a variant of fibrous dysplasia [0.03%]
软骨发育不良新证据表明其为良性纤维性发育异常的变异型
Carlos E De Andrea,Alvaro Lopez-Janeiro,Pancras C W Hogendoorn
Carlos E De Andrea
Several types of tumours and tumour-like lesions are recognised. Their classification is based mainly on the cell or tissue differentiation pathway found within the lesion. Not all tumour cells in a bone tumour differentiate towards a singl...
Spindle cell carcinoma of the breast resembling pseudoangiomatous stromal hyperplasia [0.03%]
类似假血管性间质增生的乳腺纺锤细胞癌
Andrew H S Lee,Anne-Marie O&#x;Shea,Ian O Ellis
Andrew H S Lee
Pseudoangiomatous stromal hyperplasia (PASH) is commonly present in gynaecomastia, can be seen in some mammary fibroepithelial lesions and in fibrocystic change, and rarely forms a mass. Spindle cell carcinoma of the breast can have a wide ...