PD-L1 expression is an unfavourable prognostic indicator in Asian renal cell carcinomas [0.03%]
程序性死亡配体1的表达在亚洲肾细胞癌中是不利的预后指标
Joe Yeong,Zitong Zhao,Jeffrey Chun Tatt Lim et al.
Joe Yeong et al.
Background/aims: The programmed cell death receptor 1 (PD-1) checkpoint inhibitor, nivolumab, has been approved for the treatment of metastatic renal cell carcinoma (RCC). However, the understanding of the expression and ...
Perineural invasion as a predictive factor for survival outcome in gastric cancer patients: a systematic review and meta-analysis [0.03%]
神经周围侵袭在胃癌患者生存结果预测中的作用：系统回顾和meta分析
Bochao Zhao,Wu Lv,Di Mei et al.
Bochao Zhao et al.
Aims: The prognostic significance of perineural invasion (PNI) for gastric cancer (GC) patients was under debate. This study aimed to review relevant studies and evaluate the impact of PNI on the survival outcome of GC pa...
Diagnostic value of bone marrow core biopsy patterns in lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia and description of its mutational profiles by targeted NGS [0.03%]
骨髓活检模式在淋巴浆细胞淋巴瘤/瓦尔登斯特伦巨球蛋白血症诊断中的价值及其突变图谱的描绘
Julia Garcia-Reyero,Nerea Martinez Magunacelaya,Sonia Gonzalez de Villambrosia et al.
Julia Garcia-Reyero et al.
Aims: The aim of this study was to describe the characteristics of the bone marrow infiltration found in a series of clinically defined lymphoplasmacytic lymphoma (LPL)/Waldenström macroglobulinaemia (WM) and IgM-monoclo...
Multiplex immunohistochemistry/immunofluorescence (mIHC/IF) for PD-L1 testing in triple-negative breast cancer: a translational assay compared with conventional IHC [0.03%]
用于三阴性乳腺癌PD-L1检测的多重免疫组化/免疫荧光（mIHC/IF）的转化实验与传统IHC对比研究
Joe Yeong,Tira Tan,Zi Long Chow et al.
Joe Yeong et al.
Background: Programmed death-ligand 1 (PD-L1) monoclonal antibody therapy has recently gained approval for treating metastatic triple-negative breast cancer (TNBC) -, in particular in the PD-L1+ patient subgroup of the re...
Application of 2016 WHO classification in the diagnosis of paediatric high-grade MYC-negative mature B-cell lymphoma with Burkitt-like morphological features [0.03%]
2016年WHO分类在MYC阴性儿童高度侵袭性Burkitt样成熟B细胞淋巴瘤诊断中的应用价值分析
Lei Zhang,Laura E Brown,Laurel M Bowen et al.
Lei Zhang et al.
Aims: Historically, there has been no consensus on the diagnostic classification of high-grade B-cell lymphoma (HGBCL) with morphological features of Burkitt lymphoma (BL) but no MYC gene rearrangement (MYC-negative). The...
My approach to endoscopic ultrasound-guided fine-needle aspiration biopsy specimens of the pancreas [0.03%]
我的胰腺内镜超声引导下的细针抽吸活检标本诊断方法
Newton A C S Wong
Newton A C S Wong
Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) is the optimal method for sampling lesions of the pancreas. This procedure is being performed at increasing numbers of hospitals and therefore, more and more cellular pat...
Accuracy of the revised Vienna Classification for predicting postendoscopic resection outcomes for gastric and oesophageal neoplasms: a retrospective cohort study of patients from a UK tertiary referral centre [0.03%]
改良维也纳分类预测胃食管神经病内镜切除术后转归的准确性：英国三级转诊中心患者的回顾性队列研究
Jen Kuan,Elizabeth Ratcliffe,Stephen Hayes et al.
Jen Kuan et al.
Aims: To review the effectiveness of the revised Vienna classification (rVC) at predicting histological outcome and defining the postendoscopic resection (ER) clinical management plan of gastro-oesophageal dysplasia and e...
High CXCR4 expression in adenoid cystic carcinoma of the head and neck is associated with increased risk of locoregional recurrence [0.03%]
头颈部腺样囊性癌中高CXCR4表达与局部区域复发风险增加相关
Thomas J W Klein Nulent,Robert J J van Es,Matthijs H Valstar et al.
Thomas J W Klein Nulent et al.
Aim: Treatment options for head and neck adenoid cystic carcinoma (AdCC) are limited in advanced disease. Chemokine receptor type 4 (CXCR4) is present in various tumour types, including AdCC. Upregulation is associated wi...
Multicenter Study
Journal of clinical pathology. 2020 Aug;73(8):476-482. DOI:10.1136/jclinpath-2019-206273 2020
Paraneoplastic leukemoid reactions induced by cytokine-secreting tumours [0.03%]
细胞因子分泌肿瘤所致的副肿瘤性类白血病反应
Ibrahim A Abukhiran,Judy Jasser,Sergei Syrbu
Ibrahim A Abukhiran
Paraneoplastic leukemoid reaction (PLR) is the extreme leukocytosis that occurs due to a non-haematolymphoid cytokine-secreting tumour (CST) in the absence of bone marrow infiltration by that solid tumour. The clinical presentation is widel...
Grating-based phase-contrast CT (PCCT): histopathological correlation of human liver cirrhosis and hepatocellular carcinoma specimen [0.03%]
基于光栅的相位对比CT(PCCT)与人肝硬化和肝细胞癌标本的病理组织切片相关性研究
Melanie A Kimm,Marian Willner,Enken Drecoll et al.
Melanie A Kimm et al.
Aims: To correlate signal intensities in grating-based phase-contrast CT (PCCT) images obtained at a synchrotron light source and a conventional X-ray source with tissue components in human liver cirrhosis and hepatocellu...