Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea [0.03%]
盐化古菌翻译起始因子5A修饰途径的解析
Laurence Prunetti,Michael Graf,Ian K Blaby et al.
Laurence Prunetti et al.
Translation initiation factor 5A (IF5A) is essential and highly conserved in Eukarya (eIF5A) and Archaea (aIF5A). The activity of IF5A requires hypusine, a posttranslational modification synthesized in Eukarya from the polyamine precursor s...
Arshan Nasir,Kyung Mo Kim,Violette Da Cunha et al.
Arshan Nasir et al.
The archaeal ancestor scenario (AAS) for the origin of eukaryotes implies the emergence of a new kind of organism from the fusion of ancestral archaeal and bacterial cells. Equipped with this "chimeric" molecular arsenal, the resulting cell...
Unusually High Archaeal Diversity in a Crystallizer Pond, Pomorie Salterns, Bulgaria, Revealed by Phylogenetic Analysis [0.03%]
保加利亚普莫里亚盐田结晶池中极高古菌多样性的确立及系统发育分析
Margarita Kambourova,Iva Tomova,Ivanka Boyadzhieva et al.
Margarita Kambourova et al.
Recent studies on archaeal diversity in few salterns have revealed heterogeneity between sites and unique structures of separate places that hinder drawing of generalized conclusions. Investigations on the archaeal community composition in ...
NADP-Dependent Aldehyde Dehydrogenase from Archaeon Pyrobaculum sp.1860: Structural and Functional Features [0.03%]
来自古菌Pyrobaculum sp.1860的NADP依赖性的醛脱氢酶：结构和功能特征
Ekaterina Yu Bezsudnova,Tatiana E Petrova,Natalia V Artemova et al.
Ekaterina Yu Bezsudnova et al.
We present the functional and structural characterization of the first archaeal thermostable NADP-dependent aldehyde dehydrogenase AlDHPyr1147. In vitro, AlDHPyr1147 catalyzes the irreversible oxidation of short aliphatic aldehydes at 60-85...
Thiago Rodrigues,Aline Belmok,Elisa Catão et al.
Thiago Rodrigues et al.
In recent years, archaeal diversity surveys have received increasing attention. Brazil is a country known for its natural diversity and variety of biomes, which makes it an interesting sampling site for such studies. However, archaeal commu...
Characterization of a Thermostable 8-Oxoguanine DNA Glycosylase Specific for GO/N Mismatches from the Thermoacidophilic Archaeon Thermoplasma volcanium [0.03%]
来源于高温嗜酸古菌Thermoplasma volcanium的耐热型GO/N错配特异DNA嘌呤甘露糖苷酶的鉴定与性质研究
Miki Fujii,Chieri Hata,Munetada Ukita et al.
Miki Fujii et al.
The oxidation of guanine (G) to 7,8-dihydro-8-oxoguanine (GO) forms one of the major DNA lesions generated by reactive oxygen species (ROS). The GO can be corrected by GO DNA glycosylases (Ogg), enzymes involved in base excision repair (BER...
Birth of Archaeal Cells: Molecular Phylogenetic Analyses of G1P Dehydrogenase, G3P Dehydrogenases, and Glycerol Kinase Suggest Derived Features of Archaeal Membranes Having G1P Polar Lipids [0.03%]
古菌细胞的起源：G1P脱氢酶、G3P脱氢酶和甘油激酶的分子系统发育分析表明，具有G1P极性脂质的古菌膜具有衍生特征
Shin-Ichi Yokobori,Yoshiki Nakajima,Satoshi Akanuma et al.
Shin-Ichi Yokobori et al.
Bacteria and Eukarya have cell membranes with sn-glycerol-3-phosphate (G3P), whereas archaeal membranes contain sn-glycerol-1-phosphate (G1P). Determining the time at which cells with either G3P-lipid membranes or G1P-lipid membranes appear...
Discovering Antioxidant Molecules in the Archaea Domain: Peroxiredoxin Bcp1 from Sulfolobus solfataricus Protects H9c2 Cardiomyoblasts from Oxidative Stress [0.03%]
产硫酸盐嗜热古菌科索沃硫磺泉栖生物中超氧化物歧化酶Bcp1的抗氧化分子发现及其对H9c2心肌细胞氧化应激的保护作用
Carmen Sarcinelli,Gabriella Fiorentino,Elio Pizzo et al.
Carmen Sarcinelli et al.
Peroxiredoxins (Prxs) are ubiquitous thiol peroxidases that are involved in the reduction of peroxides. It has been reported that prokaryotic Prxs generally show greater structural robustness than their eukaryotic counterparts, making them ...
Archaea and Bacteria Acclimate to High Total Ammonia in a Methanogenic Reactor Treating Swine Waste [0.03%]
高氨氮条件下猪场废水厌氧消化体系微生物适应机制研究
Sofia Esquivel-Elizondo,Prathap Parameswaran,Anca G Delgado et al.
Sofia Esquivel-Elizondo et al.
Inhibition by ammonium at concentrations above 1000 mgN/L is known to harm the methanogenesis phase of anaerobic digestion. We anaerobically digested swine waste and achieved steady state COD-removal efficiency of around 52% with no fatty-a...
Archaeal DNA Polymerase-B as a DNA Template Guardian: Links between Polymerases and Base/Alternative Excision Repair Enzymes in Handling the Deaminated Bases Uracil and Hypoxanthine [0.03%]
古菌DNA聚合酶-B作为DNA模板监护者：聚合酶与碱基/替代切除修复酶在处理脱氨基碱基尿嘧啶和次黄嘌呤方面的联系
Javier Abellón-Ruiz,Sonoko Ishino,Yoshizumi Ishino et al.
Javier Abellón-Ruiz et al.
In Archaea repair of uracil and hypoxanthine, which arise by deamination of cytosine and adenine, respectively, is initiated by three enzymes: Uracil-DNA-glycosylase (UDG, which recognises uracil); Endonuclease V (EndoV, which recognises hy...