Giuseppe Gargano,Giovanni Asparago,Filippo Spiezia et al.
Giuseppe Gargano et al.
Background: Osteoporosis results in reduced bone mass and consequent bone fragility. Small interfering RNAs (siRNAs) can be used for therapeutic purposes, as molecular targets or as useful markers to test new therapies. ...
Efficacy of hydrodilatation in frozen shoulder: a systematic review and meta-analysis [0.03%]
肩关节镜下灌洗高压注射治疗冻结肩疗效的系统评价和meta分析
Daryl Poku,Rifat Hassan,Filippo Migliorini et al.
Daryl Poku et al.
Introduction: It is unclear whether hydrodilatation is beneficial in the management of frozen shoulder compared with other common conservative management modalities. This systematic review evaluates the efficacy of hydrod...
Mobilization-based engraftment of haematopoietic stem cells: a new perspective for chemotherapy-free gene therapy and transplantation [0.03%]
基于动员的造血干细胞植入：化疗无基因治疗和移植的新视角
Daniele Canarutto,Attya Omer Javed,Gabriele Pedrazzani et al.
Daniele Canarutto et al.
Introduction: In haematopoietic stem cell transplantation (HSCT), haematopoietic stem cells (HSCs) from a healthy donor replace the patient's ones. Ex vivo HSC gene therapy (HSC-GT) is a form of HSCT in which HSCs, usuall...
Benjamin Krishna,Mark Wills,Nyaradzai Sithole
Benjamin Krishna
Introduction: Long COVID is a chronic condition that follows after acute COVID-19 and is characterized by a wide range of persistent, cyclic symptoms. Sou...
Silvia Morlino,Marco Castori
Silvia Morlino
Background: Joint hypermobility (JHM) is a common physical trait. It may occur alone or in combination with musculoskeletal (MSK) pain, outside or within more complex phenotypes. Hypermobility spectrum disorders (HSD) are...
The SSS revolution in fungal diagnostics: speed, simplicity and sensitivity [0.03%]
SSS革命推动真菌诊断：快速、简便和高灵敏度
Jacob Baker,David W Denning
Jacob Baker
Introduction: Fungal disease has historically presented a diagnostic challenge due to its often non-specific clinical presentations, relative infrequency and reliance on insensitive and time-intensive fungal culture. ...
Filippo Migliorini,Gianluca Vecchio,Christian David Weber et al.
Filippo Migliorini et al.
Introduction: Transient bone osteoporosis (TBO) is characterized by persistent pain, loss of function, no history of trauma and magnetic resonance image (MRI) findings of bone marrow edema. ...
Jacob Brolly,David R Chadwick
Jacob Brolly
Background: Coronavirus disease 2019 (COVID-19) and human immunodeficiency virus (HIV) are intersecting pandemics, with implications for care at an individual and global scale. ...
Drug repurposing for COVID-19: current evidence from randomized controlled adaptive platform trials and living systematic reviews [0.03%]
药物再利用在COVID-19治疗中的应用：随机对照自适应平台试验和动态系统评价的当前证据
Yolanda Augustin,Henry M Staines,Thirumalaisamy P Velavan et al.
Yolanda Augustin et al.
Introduction: The coronavirus disease 2019 (COVID-19) pandemic resulted in a race to develop effective treatments largely through drug repurposing via adaptive platform trials on a global scale. Drug repurposing trials ha...
Ilaria Brentari,Mariia Zadorozhna,Michela Alessandra Denti et al.
Ilaria Brentari et al.
Introduction: Ribonucleic acid (RNA) therapeutics are a new class of drugs whose importance is highlighted by the growing number of molecules in the clinic. ...