Jacob Brolly,David R Chadwick
Jacob Brolly
Background: Coronavirus disease 2019 (COVID-19) and human immunodeficiency virus (HIV) are intersecting pandemics, with implications for care at an individual and global scale. ...
Drug repurposing for COVID-19: current evidence from randomized controlled adaptive platform trials and living systematic reviews [0.03%]
药物再利用在COVID-19治疗中的应用：随机对照自适应平台试验和动态系统评价的当前证据
Yolanda Augustin,Henry M Staines,Thirumalaisamy P Velavan et al.
Yolanda Augustin et al.
Introduction: The coronavirus disease 2019 (COVID-19) pandemic resulted in a race to develop effective treatments largely through drug repurposing via adaptive platform trials on a global scale. Drug repurposing trials ha...
Ilaria Brentari,Mariia Zadorozhna,Michela Alessandra Denti et al.
Ilaria Brentari et al.
Introduction: Ribonucleic acid (RNA) therapeutics are a new class of drugs whose importance is highlighted by the growing number of molecules in the clinic. ...
Management of complex regional pain syndrome in trauma and orthopaedic surgery-a systematic review [0.03%]
创伤和骨科手术中复杂区域疼痛综合征的管理-系统评价
Abdel Saed,Greg Neal-Smith,Scott Fernquest et al.
Abdel Saed et al.
Introduction: Complex regional pain syndrome (CRPS) is a neurological pain disorder that is challenging to diagnose and manage, resulting in increased morbidity and costs. It most commonly occurs following traumatic injur...
Hanna Tabisz,Aleksandra Modlinska,Sławomir Kujawski et al.
Hanna Tabisz et al.
Introduction: Whole-body cryotherapy (WBC) is a controlled exposure of the whole body to cold to gain health benefits. In recent years, data on potential applications of WBC in multiple clinical settings have emerged. ...
Optimizing lipid management-impact of the COVID 19 pandemic upon cardiovascular risk in England [0.03%]
血脂管理的优化——英国新冠肺炎疫情对心血管疾病风险的影响
Julia L Newton,Joseph Hamed,Helen Williams et al.
Julia L Newton et al.
Background: We sought to understand the impact of the COVID-19 pandemic on lipid-lowering therapy prescribing as a potential cause of the excess cardiovascular mortality seen post-pandemic in England. We examined temporal...
Luca Miranda,Marco Quaranta,Francesco Oliva et al.
Luca Miranda et al.
Background: Chronic low back pain, common from the sixth decade, negatively impacts the quality of life of patients and health care systems. Recently, mesenchymal stem cells (MSCs) have been introduced in the management o...
Alex McKeown
Alex McKeown
Introduction: Integrated care is an established approach to delivery in parts of the healthcare infrastructure, and an ideal which, it is claimed, should be realized system-wide. Its ethical weight derives from its defenc...
Loneliness-a clinical primer [0.03%]
孤独-临床指南
Zohar Lederman
Zohar Lederman
Introduction: loneliness is prevalent worldwide. It is also associated with an increased risk for depression, high blood pressure, cardiovascular disease, stroke and early death. As such, loneliness is a major public heal...