Sports injuries in children [0.03%]
儿童运动损伤
Chezhiyan Shanmugam,Nicola Maffulli
Chezhiyan Shanmugam
Introduction: Sports injuries in children affect both growing bone and soft tissues, and can result in damage of growth mechanisms with subsequent lifelong, growth disturbance. This clinical review unfolds the incidence a...
Anthony R Isles,Lawrence S Wilkinson
Anthony R Isles
Introduction: The chemical marking of the DNA and surrounding histone proteins represent some of the means by which gene expression is controlled. Many of these epigenetic modifications are pre-programmed and are an impor...
Gopalakrishnan Netuveli,David Blane
Gopalakrishnan Netuveli
Background: The quality of life of elderly people has become relevant with the demographic shift that has resulted in greying of population. There are indications that concepts and concerns related to quality of life in o...
Gastric cancer [0.03%]
胃癌
Paul Lochhead,Emad M El-Omar
Paul Lochhead
Background: Gastric cancer remains a major cause of mortality and morbidity worldwide, and the total number of gastric cancer cases is predicted to rise as a result of population growth. The pathogenesis of gastric cancer...
O6-Methylguanine-DNA methyltransferase inactivation and chemotherapy [0.03%]
O6-甲基鸟嘌呤DNA-甲基转移酶失活与化疗耐药关系的研究进展
Barbara Verbeek,Thomas D Southgate,David E Gilham et al.
Barbara Verbeek et al.
Introduction: Alkylating agents are frequently used in the chemotherapy of many types of cancer. This group of drugs mediates cell death by damaging DNA and therefore, understandably, cellular DNA repair mechanisms can in...
Background: Osteoporosis (OP) is a metabolic bone disease producing reduction in bone mass with consequent bone fragility. Circular ribonucleic acid (CircRNA) is a form of RNA that forms a loop structure rather than a lin...