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Continuous versus bolus norepinephrine administration to treat hypotension after induction of general anaesthesia in low-to-moderate risk noncardiac surgery patients: a randomised trial [0.03%] 连续输注去甲肾上腺素与间歇推注治疗非心脏手术低中风险患者全身麻醉后低血压的随机对照研究
Kristen K Thomsen,Finn Külls,Christina Vokuhl et al. Kristen K Thomsen et al.
Background: Hypotension after induction of general anaesthesia (postinduction hypotension) is common in patients undergoing noncardiac surgery and frequently requires treatment with vasopressors such as norepinephrine. We...
Development and analysis of a remimazolam pharmacokinetics and pharmacodynamics model with proposed dosing and concentrations for anaesthesia and sedation [0.03%] 雷米唑胺药代动力学和药效学模型的开发与分析及麻醉和镇静给药和浓度建议
Douglas J Eleveld,Pieter J Colin,Johannes P Van den Berg et al. Douglas J Eleveld et al.
Background: Pharmacokinetic-pharmacodynamic (PK-PD) models of remimazolam and their covariate relationships are useful for understanding drug disposition and predicting drug effects. Although clinical studies have shown t...
A nationwide approach to reduction in anaesthetic gas use: the Dutch Approach to decarbonising anaesthesia. Comment on Br J Anaesth 2025; 134: 1146-52 [0.03%] 全国范围减少麻醉气体使用的策略：荷兰在麻醉去碳化方面的做法。评论《British Journal of Anaesthesia》2025; 134: 1146-52
Peter Kranke,Giovanni Landoni,Laurentiu Marin et al. Peter Kranke et al.
Thoracic segmental spinal anaesthesia: expanding applications while keeping it safe [0.03%] thoracic 椎管内麻醉：扩大适应症并确保其安全性
Naresh W Paliwal,Imran A Khan Naresh W Paliwal
A probabilistic model of behavioural emergence from general anaesthesia in mice [0.03%] 小鼠从全身麻醉中行为觉醒的概率模型
Martha E Stone,Max B Kelz,Alex Proekt et al. Martha E Stone et al.
Background: Time to emergence from general anaesthesia is highly variable between individuals. This variability has been attributed to individual differences in anaesthetic sensitivity. However, this hypothesis has not be...
J Robert Sneyd,Anthony R Absalom J Robert Sneyd
Patient-controlled sedation using inhaled anaesthetics provides several potential advantages. In a study of healthy volunteers, low-dose inhaled sevoflurane impaired volunteers' ability to complete a button-press task without significant ca...
Q19.12024 Editorial British journal of anaesthesia. 2025 May;134(5):1278-1281. DOI:10.1016/j.bja.2025.02.026 2025
Global synergy in anaesthesia training: the crucial role of international collaborations for trainees from low-resource countries [0.03%] 全球麻醉培训中的协同作用：国际合作对低资源国家受训者的关键作用
Baththirange Malaka Munasinghe,Jayasuriya N J A Sahan Sachitra,Martin F Mayall Baththirange Malaka Munasinghe
Parafacial GABAergic neurone ablation induces behavioural resistance to volatile anaesthetic-induced hypnosis without reducing sleep [0.03%] 伏隔区GABA能神经元消融术可诱导行为抵抗吸入麻醉剂所致的催眠而不减少睡眠
Toshihiro Imamura,Andrzej Z Wasilczuk,Sarah L Reitz et al. Toshihiro Imamura et al.
Background: It is hypothesised that general anaesthetics co-opt the neural circuits regulating endogenous sleep and wakefulness to produce hypnosis. To further probe this association, we focused on the GABAergic neurones ...
Associations between anaesthetic dose-adjusted intraoperative EEG alpha power, processing speed, and postoperative delirium: analysis of data from three prospective studies [0.03%] 麻醉剂量校正的术中EEGα功率与处理速度及术后谵妄的关系：三项前瞻性研究数据的分析
Melody Reese,Mary Cooter Wright,Ken C Roberts et al. Melody Reese et al.
Background: We previously have shown that low intraoperative EEG alpha power is associated with impaired preoperative cognition, a delirium risk factor, and that intraoperative anaesthetic-dose-adjusted EEG bispectral ind...
Utilising high-volume spinal anaesthesia as an alternative to general anaesthesia: lessons from Gaza [0.03%] 高位脊麻在加沙地带作为全身麻醉的替代方法应用于高容量手术的教训
Iyad Abukarsh,Abdulrahman Abu Motlaq,Abdalmajeed Atallah et al. Iyad Abukarsh et al.