Abeer Shaheen,Jamal Khaddam,Fadi Kesh
Abeer Shaheen
Background: Keloid is a benign fibrous growth, which presents in scar tissue of predisposed individuals. It is a result of irregular wound healing, but the exact mechanism is unknown. However, several factors may play a r...
Randomized placebo control study of insulin sensitizers (Metformin and Pioglitazone) in psoriasis patients with metabolic syndrome (Topical Treatment Cohort) [0.03%]
代谢综合征银屑病患者使用胰岛素增敏剂（二甲双胍和吡格列酮）的随机双盲对照研究（外用治疗组）
Surjit Singh,Anil Bhansali
Surjit Singh
Background: Increased prevalence of metabolic syndrome (MS) is observed in psoriasis. Metformin has shown improvement in cardiovascular risk factors while pioglitazone demonstrated anti proliferative, anti-inflammatory an...
Randomized Controlled Trial
BMC dermatology. 2016 Aug 17;16(1):12. DOI:10.1186/s12895-016-0049-y 2016
A multicenter, randomized, open-label pilot trial assessing the efficacy and safety of etanercept 50 mg twice weekly followed by etanercept 25 mg twice weekly, the combination of etanercept 25 mg twice weekly and acitretin, and acitretin alone in patients with moderate to severe psoriasis [0.03%]
评估依那西普联合雅美罗和雅美罗单药治疗中重度斑块状银屑病患者的疗效和安全性的多中心随机开放标签Ⅱ期临床试验
Joo-Heung Lee,Jai-Il Youn,Tae-Yoon Kim et al.
Joo-Heung Lee et al.
Background: Etanercept, a soluble tumor necrosis factor receptor, and acitretin have been shown to be effective in treating psoriasis. Acitretin is widely used in Korea. However, the combination of etanercept plus acitret...
Randomized Controlled Trial
BMC dermatology. 2016 Jul 25;16(1):11. DOI:10.1186/s12895-016-0048-z 2016
Hossein Mortazavi,Amirhooshang Ehsani,Seyed Sajed Sajjadi et al.
Hossein Mortazavi et al.
Background: Allergic contact dermatitis is a common disorder in adults and children alike and appears to be on the increase. The purpose of this study was to determine the sensitization trends in Iranian children with con...
Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice [0.03%]
12-十四烷酰佛波醇十三酸酯致小鼠银屑病样皮损的系统性炎症及动脉粥样硬化的影响研究
Marie Madsen,Peter Riis Hansen,Lars Bo Nielsen et al.
Marie Madsen et al.
Background: Risk of cardiovascular disease is increased in patients with psoriasis, but molecular mechanisms linking the two conditions have not been clearly established. Lack of appropriate animal models has hampered gen...
Enzymatic debridement for the treatment of severely burned upper extremities - early single center experiences [0.03%]
酶脱残的严重烧伤上肢治疗—早期单中心经验总结
Tomke Cordts,Johannes Horter,Julian Vogelpohl et al.
Tomke Cordts et al.
Background: Severe burns of hands and arms are complex and challenging injuries. The Standard of care (SOC) - necrosectomy with skin grafting - is often associated with poor functional or aesthetic outcome. Enzymatic debr...
The first Danish family reported with an AQP5 mutation presenting diffuse non-epidermolytic palmoplantar keratoderma of Bothnian type, hyperhidrosis and frequent Corynebacterium infections: a case report [0.03%]
一丹麦家系首报AQP5突变导致的博滕型弥漫性非表皮松解型掌跖角化病、多汗症和频繁柯萨奇病毒感染：病例报告
Anne Bruun Krøigård,Liv Eline Hetland,Ole Clemmensen et al.
Anne Bruun Krøigård et al.
Background: An autosomal dominant form of diffuse non-epidermolytic palmoplantar keratoderma, palmoplantar keratoderma of Bothnian type, is caused by mutations in the AQP5 gene encoding the cell-membrane water channel pro...
Case Reports
BMC dermatology. 2016 Jun 3;16(1):7. DOI:10.1186/s12895-016-0044-3 2016
Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo [0.03%]
热处理介导的紫外线损伤角质形成细胞凋亡的抑制作用
Leslie Calapre,Elin S Gray,Sandrine Kurdykowski et al.
Leslie Calapre et al.
Background: UV radiation induces significant DNA damage in keratinocytes and is a known risk factor for skin carcinogenesis. However, it has been reported previously that repeated and simultaneous exposure to UV and heat ...
A case of erythrodermia from exacerbated psoriasis vulgaris due to treatment of acute hepatitis C [0.03%]
慢性重度银屑病继发红皮症1例
Eva Lemmenmeier,Barbara Gaus,Patrick Schmid et al.
Eva Lemmenmeier et al.
Background: Skin side effects during interferon-alpha and ribavirin treatment are common, but autoimmune dermatosis triggered by interferon-alpha is rare. We describe a case of erythrodermia from exacerbated psoriasis dur...
Case Reports
BMC dermatology. 2016 May 26;16(1):5. DOI:10.1186/s12895-016-0042-5 2016
Nipple adenoma in a female patient presenting with persistent erythema of the right nipple skin: case report, review of the literature, clinical implications, and relevancy to health care providers who evaluate and treat patients with dermatologic conditions of the breast skin [0.03%]
女性右侧乳头皮肤持续性红斑的乳头腺瘤1例及相关文献复习、临床意义和乳房皮肤病患诊治医务人员的相关性分析
Gina P Spohn,Shannon C Trotter,Gary Tozbikian et al.
Gina P Spohn et al.
Background: Nipple adenoma is a very uncommon, benign proliferative process of lactiferous ducts of the nipple. Clinically, it often presents as a palpable nipple nodule, a visible nipple skin erosive lesion, and/or with ...
Case Reports
BMC dermatology. 2016 May 20;16(1):4. DOI:10.1186/s12895-016-0041-6 2016