Topical application of RTA 408 lotion activates Nrf2 in human skin and is well-tolerated by healthy human volunteers [0.03%]
RTA 408外用液体制剂可激活人体皮肤中的Nrf2并被健康志愿者良好耐受
Scott A Reisman,Angela R Goldsberry,Chun-Yue I Lee et al.
Scott A Reisman et al.
Background: Topical application of the synthetic triterpenoid RTA 408 to rodents elicits a potent dermal cytoprotective phenotype through activation of the transcription factor Nrf2. Therefore, studies were conducted to i...
Clinical Trial
BMC dermatology. 2015 Jul 14:15:10. DOI:10.1186/s12895-015-0029-7 2015
Effect of etanercept therapy on psoriasis symptoms in patients from Latin America, Central Europe, and Asia: a subset analysis of the PRISTINE trial [0.03%]
安纳白介素治疗对来自拉丁美洲、中欧和亚洲的银屑病患者症状的影响：PRISTINE试验的一个子集分析
L Kemeny,M Amaya,P Cetkovska et al.
L Kemeny et al.
Background: Psoriasis prevalence and characteristics in Asia, Central Europe, and Latin America have not been thoroughly investigated and there are no large trials for biologic treatments for patients from these regions. ...
Randomized Controlled Trial
BMC dermatology. 2015 May 21:15:9. DOI:10.1186/s12895-015-0028-8 2015
Effects of tofacitinib on lymphocyte sub-populations, CMV and EBV viral load in patients with plaque psoriasis [0.03%]
托法替尼对斑块状银屑病患者淋巴细胞亚群，CMV和EBV病毒载量的影响
Fernando Valenzuela,Kim A Papp,David Pariser et al.
Fernando Valenzuela et al.
Background: Plaque psoriasis is a debilitating skin condition that affects approximately 2% of the adult population and for which there is currently no cure. Tofacitinib is an oral Janus kinase inhibitor that is being inv...
Clinical Trial
BMC dermatology. 2015 May 8:15:8. DOI:10.1186/s12895-015-0025-y 2015
Topical treatment with fresh human milk versus emollient on atopic eczema spots in young children: a small, randomized, split body, controlled, blinded pilot study [0.03%]
关于婴幼儿异位性皮炎局部 topical 使用新鲜人乳与润肤剂的对比研究：随机分割对照盲法试点实验
Teresa Løvold Berents,Jørgen Rønnevig,Elisabeth Søyland et al.
Teresa Løvold Berents et al.
Background: Public health nurses report on effects of fresh human milk as treatment for conjunctivitis, rhinitis and atopic eczema (AE), the latter being highly prevalent in early childhood. Emollients and topical cortico...
Randomized Controlled Trial
BMC dermatology. 2015 May 4:15:7. DOI:10.1186/s12895-015-0027-9 2015
Subjective stress reactivity in psoriasis - a cross sectional study of associated psychological traits [0.03%]
银屑病患者应激反应性及相关的心理特征横断面研究
Charlotta Remröd,Karin Sjöström,Åke Svensson
Charlotta Remröd
Background: Stress or psychological distress is often described as a causative or maintaining factor in psoriasis. Psychological traits may influence the appraisal, interpretation and coping ability regarding stressful si...
Validation of the global resource of eczema trials (GREAT database) [0.03%]
全球特应性皮炎临床试验数据库(GREAT数据库)的验证
Helen Nankervis,Alison Devine,Hywel C Williams et al.
Helen Nankervis et al.
Background: Eczema (syn. Atopic Eczema or Atopic Dermatitis) is a chronic, relapsing, itchy skin condition which probably results from a combination of genetic and environmental factors. The Global Resource of EczemA Tria...
Photoallergic reaction in a patient receiving vandetanib for metastatic follicular thyroid carcinoma: a case report [0.03%]
凡德他尼治疗分化型甲状腺癌的光变态反应1例报告
Jennifer Goldstein,Anisha B Patel,Jonathan L Curry et al.
Jennifer Goldstein et al.
Background: Novel targeted agents have been increasingly developed and tested in clinical trials over the past 5-10 years, many with unknown and unanticipated side effects. We describe here a case of a patient with a hist...
Clinical Trial
BMC dermatology. 2015 Feb 13:15:2. DOI:10.1186/s12895-015-0022-1 2015
Exploring the association between Morgellons disease and Lyme disease: identification of Borrelia burgdorferi in Morgellons disease patients [0.03%]
梅尔加龙病和莱姆病之间关联的探索：从梅尔加龙病患者身上鉴定出伯氏疏螺旋体
Marianne J Middelveen,Cheryl Bandoski,Jennie Burke et al.
Marianne J Middelveen et al.
Background: Morgellons disease (MD) is a complex skin disorder characterized by ulcerating lesions that have protruding or embedded filaments. Many clinicians refer to this condition as delusional parasitosis or delusiona...
Digital photography in skin cancer screening by mobile units in remote areas of Brazil [0.03%]
数字摄影在巴西偏远地区的流动皮肤癌筛查中的应用
Carlos Eduardo Goulart Silveira,Thiago Buosi Silva,José Humberto Guerreiro Tavares Fregnani et al.
Carlos Eduardo Goulart Silveira et al.
Background: Non-melanoma skin cancer (NMSC) is one of the most common neoplasms in the world. Despite the low mortality rates, NMSC can still cause severe sequelae when diagnosed at advanced stages. Malignant melanoma, th...
Maryam Salimi,Graham Ogg
Maryam Salimi
Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung,...