Therapeutic effects of silibinin in preclinical animal models of gastrointestinal cancers: a systematic review and meta‑analysis [0.03%]
白飞灵对胃肠肿瘤的治疗作用：系统评价和荟萃分析
Davood Mohammadi,Amir Hossein Aghayan,Diba Mohammadi et al.
Davood Mohammadi et al.
Background: Gastrointestinal (GI) cancers represent a leading cause of cancer-related mortality worldwide. Silibinin, the primary active constituent of milk thistle, possesses anti-proliferative, pro-apoptotic, and anti-i...
Malignancy in mirror image anatomy reveals situs inversus totalis as an anatomic modifier of oncologic care [0.03%]
镜像解剖中的恶性肿瘤揭示了完全内脏反位是一种需要修正的解剖标志以优化肿瘤治疗效果的因素
Zhongan Liu,Ganxin Wang,Kai Huang et al.
Zhongan Liu et al.
Background: Situs inversus totalis (SIT) is a rare congenital laterality anomaly characterized by complete mirror-image transposition of the thoracic and abdominal viscera. Although SIT is not a proven cancer-predispositi...
Association of immunohistochemistry-based molecular subtypes with adnexal involvement in endometrial cancer [0.03%]
基于免疫组化分子亚型的子宫内膜癌副滋养物受累情况及其临床病理特征分析
Oğuz Kaan Köksal,Hande Nur Öncü,Firdevs Şahin Duran et al.
Oğuz Kaan Köksal et al.
Background: Adnexal involvement in endometrial cancer is traditionally regarded as an anatomical spread pattern within FIGO stage IIIA; however, its biological heterogeneity remains incompletely understood. The 2023 FIGO ...
Clinical characteristics and long-term treatment outcomes in childhood myelodysplastic neoplasm: a nationwide population-based study in Korea [0.03%]
韩国全国人群队列研究中儿童髓系肿瘤的临床特征和长期治疗结局
Minwoong Kang,Eun Sang Yi,Jung Yoon
Minwoong Kang
Background: Childhood myelodysplastic neoplasm (cMDS) is a rare condition with distinct biological and clinical characteristics. To characterize the epidemiological features of cMDS, including incidence, demographics, and...
Safety and tolerability of PARP inhibitors in cancer patients: a network meta-analysis of randomized controlled trials [0.03%]
聚腺苷二磷酸核糖聚合酶抑制剂的安全性和耐受性：随机对照试验的网络meta分析
Chenyu Wei,Shujing Liu,Jiexuan Hu et al.
Chenyu Wei et al.
Background: Poly(ADP-ribose) polymerase inhibitors (PARPi) for the treatment of homologous recombination (HR)-deficient cancers have revolutionized cancer treatment in recent years. Despite documented clinical benefits, t...
Immunohistochemical evaluation of molecular subtypes in muscle invasive bladder cancer with demographic correlation [0.03%]
肌层浸润性膀胱癌的分子亚型免疫组化评估及人口统计学关联分析
Pranita Mohanty,Megha Subhangini
Pranita Mohanty
Background: Muscle-invasive bladder cancer (MIBC) is a biologically heterogeneous malignancy with variable clinical outcomes. Molecular subtyping has improved understanding of tumor biology and therapeutic stratification....
Uncovering the mechanism of DCLK3 in colorectal cancer progression through WGCNA and machine learning [0.03%]
通过WGCNA和机器学习揭示DCLK3在结直肠癌进展中的机制
Lu Yang,Yanru Han,Juanjuan Ji et al.
Lu Yang et al.
Background: Colorectal cancer (CRC) is a prevalent malignant tumor of the digestive tract with high morbidity and mortality rates. Although doublecortin like kinase 3 (DCLK3) is upregulated in CRC and promotes disease pro...
CXCR6 and its correlated G protein-coupled receptors and PI3K-AKT pathways were associated with the progression of thyroid cancer [0.03%]
趋化因子受体CXCR6及其相关G蛋白偶联受体和PI3k-AKT通路与甲状腺癌进展有关
Yiting Yao,Linlang Huang,Rui Xia et al.
Yiting Yao et al.
Background: Immunogenic cell death (ICD) is closely linked to thyroid cancer (THCA). We mined ICD-linked prognostic genes for survival predictors and unpacked their potential biology. ...
Prognostic value of tertiary lymphoid structures in high-risk esophageal squamous cell carcinoma following neoadjuvant chemoimmunotherapy [0.03%]
新辅助化疗免疫治疗后高危食管鳞癌患者三级淋巴器官的预后价值分析
Dongdong Huang,Yuejun Han,Hui Wu et al.
Dongdong Huang et al.
Background: Tertiary lymphoid structures (TLSs) are implicated in anti-tumor immunity. However, their prognostic value in esophageal squamous cell carcinoma (ESCC) following neoadjuvant chemoimmunotherapy (NCI) remains un...
Factors contributing to the missed diagnosis of incidental gallbladder cancer (IGBC): an integrated analysis of clinical features and ultrasound radiomics [0.03%]
意外型胆囊癌漏诊因素：临床特征与超声影像组学综合分析
Zhiping Pan,Xu Sun,Zhenhua Shen et al.
Zhiping Pan et al.
Background: Incidental gallbladder cancer (IGBC) is often diagnosed only during or after cholecystectomy, and preoperative identification remains challenging. This study preliminarily explored factors contributing to IGBC...