NAT10 promotes the glycolysis of retinoblastoma through ac4C modification of PFKFB3 mRNA [0.03%]
NAT10通过促进PFKFB3 mRNA的ac4C修饰来促进视网膜母细胞瘤糖酵解
Zhen Li,Weiwei Xie,Layi Wang et al.
Zhen Li et al.
Retinoblastoma (RB) is the most prevalent primary intraocular malignancy in children. N-acetyltransferase-like protein 10 (NAT10)-mediated N4-acetylcytidine (ac4C) modification is involved in regulating cancer progression. This study aimed ...
Multiple-day dexamethasone for controlling delayed chemotherapy-induced nausea and vomiting with low-emetic-risk chemotherapy [0.03%]
使用低致吐性化疗药物治疗的延迟性化疗引起的恶心呕吐多次给药地塞米松控制临床试验
Akari Yamashita,Toshinobu Hayashi,Mototsugu Shimokawa et al.
Akari Yamashita et al.
Pan-cancer analysis of TRPV1: a novel immune infiltration-related biomarker for tumor prognosis and immunotherapy response prediction [0.03%]
TRPV1的泛癌症分析：一种与免疫浸润相关的肿瘤预后和免疫治疗反应预测新型生物标志物
Feixiang Wang,Boyun Deng,Maohua Qin et al.
Feixiang Wang et al.
There were several studies on Transient receptor potential vanilloid 1 (TRPV1), the research on TRPV1 in cancer remains unclear. The expression, prognostic, single-cell value, immune cell infiltration, and immune check-point (ICI) of TRPV1 ...
Early termination of NCT04617067, a phase II, open label, clinical trial of oral paricalcitol in combination with gemcitabine and NAB-paclitaxel therapy in advanced pancreatic cancer [0.03%]
提前终止NCT04617067：一项二期、开放标签、口服派西洛汀与吉西他滨和白蛋白结合型紫杉醇联合治疗晚期胰腺癌的临床试验
David Easty,Ray McDermott,Adrian G Murphy et al.
David Easty et al.
Molecular features of early- vs. late-onset gastric cancer: a systematic review and meta-analysis [0.03%]
早发和晚发胃癌的分子特征系统评价和meta分析
Xinmei Lin,Wenhan Shi,Zitong Zhou et al.
Xinmei Lin et al.
Background: Early-onset gastric cancer (EOGC), diagnosed before age 50, is characterized by distinct clinicopathological features, though its molecular landscape remains poorly defined. ...
Scrutinizing the potential role of non-coding RNAs as biomarkers in Egyptian females with early and metastatic breast cancer [0.03%]
探究非编码RNA在埃及早期和晚期乳腺癌女性患者中作为生物标志物的潜力
Eman ElAlfy,Nourhan E Gaber,Madiha H Helmy et al.
Eman ElAlfy et al.
Comparative analysis of prevalences of sensorineural hearing loss from chemoradiotherapy versus radiotherapy in head and neck cancer patients: a systematic review and meta-analysis [0.03%]
头颈部癌症患者接受化学放射治疗与单纯放射治疗后感音神经性听力损失患病率的比较分析：系统评价和Meta分析
John Bukuru,Olivier Sibomana
John Bukuru
Introduction: Head and neck cancer (HNC) is the seventh most prevalent cancer globally. Chemoradiotherapy (CRT) and radiotherapy (RT) are the two most common treatment modalities for HNC. However, both treatments are asso...
Baseline ¹8F-FDG PET/CT radiomics predict early progression and survival in small cell lung cancer [0.03%]
基线¹⁸F-FDG PET/CT影像组学预测小细胞肺癌的早期进展和生存期
Cheng-Yin Liu,Li-Fan Lin,Chen-Liang Tsai et al.
Cheng-Yin Liu et al.
Background: To determine whether baseline ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) radiomic markers of thoracic tumor burden and metabolic heterogeneity predict early pr...
T-cell exhaustion indicator characterizes the tumor microenvironment landscape and predicts colon adenocarcinoma prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing [0.03%]
T细胞衰竭标志物通过整合单细胞RNA测序和批量RNA测序表征肿瘤微环境并预测结肠腺癌预后
Haifeng Sun,Ning Hu,Shaowei Ma et al.
Haifeng Sun et al.
Background: Colon adenocarcinoma (COAD) is the most common type of colon cancer, posing a significant threat to public health. In the tumor microenvironment (TME), T cells differentiate into terminally exhausted T cells (...
A prognostic nomogram for elderly patients with inoperable esophageal cancer undergoing intensity-modulated radiotherapy [0.03%]
不可手术的老年食管癌患者接受调强放疗的预后列线图模型
Hailiang Zhang,Yukang Yang,Rong Li et al.
Hailiang Zhang et al.
Objectives: To develop and validate a prognostic nomogram incorporating clinical and nutritional factors for individualized survival prediction in elderly patients with inoperable esophageal squamous cell carcinoma (ESCC)...