Validation of the C-WATCH score for predicting severity in patients with upper gastrointestinal bleeding at a tertiary public hospital in Lima, Peru [0.03%]
在秘鲁利马一家三级公立医院中验证C-WATCH评分在预测上消化道出血患者严重程度方面的有效性
Jorge Espinoza-Ríos,Renatto Ruiz-Cortez,Brenda Santiago et al.
Jorge Espinoza-Ríos et al.
Background: Upper gastrointestinal bleeding (UGIB) remains one of the most common emergencies in gastroenterology, with mortality rates reaching 14% in some settings. Despite advances in management, mortality has remained...
Dual GIP/GLP-1 receptor agonist tirzepatide ameliorates hepatic steatosis and inflammatory responses in a MASLD mouse model associated with the CCL2/CCR2 axis [0.03%]
双GIP和GLP-1受体激动剂tirzepatide通过CCL2/CCR2轴改善MASLD小鼠模型的肝脂肪变性和炎症反应
Yongning Pan,Fanfan Song,Xuehua Liu et al.
Yongning Pan et al.
Background/objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common multisystem chronic progressive liver disease with a rising burden. Tirzepatide (TZP), a dual agonist of glucose-dependen...
Training satisfaction, competency gaps and well-being in gastroenterology residency in Spain: results of a national SEPD survey [0.03%]
西班牙胃肠病学住院医师培训满意度、胜任力差距和幸福感：SEPD全国调查结果
Marisa Iborra,María Dolores Martín-Arranz,Judith Gómez-Camarero et al.
Marisa Iborra et al.
Objective: To explore the training experience, competency needs and professional wellbeing of Gastroenterology trainees in Spain, with a particular focus on factors associated with burnout. ...
Association of red blood cell distribution width to albumin ratio with all-cause and cardiovascular mortality among adults with MASLD [0.03%]
红细胞分布宽度与白蛋白比率与MASLD成人全因和心血管死亡率的相关性
Ze-Bin Ni,Lian-Zhen Huang,Qi-Rong Yao et al.
Ze-Bin Ni et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health burden. Identifying robust prognostic biomarkers is crucial for early risk stratification. The red blood cell distrib...
Post-splenectomy early biochemical trajectories and predictors in 935 patients with Wilson disease: a group-based trajectory modeling study [0.03%]
935例威尔森病患者术后早期生化转归及预测指标：基于聚类的轨迹模型研究
Xiuquan Shi,Sihuan Zhu,Ning Sang et al.
Xiuquan Shi et al.
Background: Splenectomy is commonly used to alleviate portal hypertension-related hypersplenism in patients with Wilson's disease (WD) cirrhosis. However, early post-splenectomy biochemical responses vary substantially am...
Risk factors for residual cancer and lymph node metastasis after non-curative endoscopic resection of colorectal cancer: a multicenter retrospective study [0.03%]
非治愈性内镜下切除术后大肠癌残留病灶及淋巴结转移的危险因素分析——多中心回顾性研究
Soo Young Oh,Hyung-Hoon Oh,Young Il Kim et al.
Soo Young Oh et al.
Background and aims: Following a non-curative endoscopic resection of T1 colorectal cancer, current guidelines recommend additional surgery based on high-risk pathological features. However, the actual rates of residual d...
Construction and validation of a machine learning-based prediction model for social isolation in patients with colorectal cancer after stoma surgery [0.03%]
基于机器学习的预测模型在结直肠癌造口术患者社会孤立感中的构建与验证
Wenqian Zhang,Liangliang Qu
Wenqian Zhang
Objective: To investigate the current status and influencing factors of social alienation in patients with enterostomy after colorectal cancer surgery, and to establish a risk prediction model for social alienation in thi...
A linear clinical prediction model and nomogram evaluating risk of portal vein thrombosis in liver cirrhosis [0.03%]
一种评估肝硬化患者门静脉血栓形成的线性临床预测模型及评分图表
Zian Wang,Feng Jiang,Jinglan Jin et al.
Zian Wang et al.
Introduction: As one of the complications of liver cirrhosis, portal vein thrombosis (PVT) brings a significant clinical challenge. To find the predictive clinical variables evaluating the probability of PVT, a prediction...
Association of a novel Fat-Muscle-BMI Index (FMBI) with NAFLD, liver fibrosis, and atherosclerotic cardiovascular disease risk: a cross-sectional study in 1,592 Chinese adults [0.03%]
新型Fat-Muscle-BMI指数（FMBI）与非酒精性脂肪肝、肝纤维化和动脉粥样硬化心血管病风险相关性的横断面研究：对中国1592名成年人的研究
Xiaokang Wu,Xinjiang Hou,Jiafeng Yin et al.
Xiaokang Wu et al.
Background: Non-alcoholic fatty liver disease (NAFLD) is a global burden with unmet non-invasive biomarker needs; BMI and FMRs have limitations, and their combined index FMBI is unstudied. We aim to explore FMBI's associa...
ETV4 as a potential target gene for alleviating proliferation metastasis of HCC [0.03%]
靶向调控ETV4基因对抗肝癌增殖侵袭功能的研究
Yuan Yuan,Qinglin Tan,Maolin Zhu et al.
Yuan Yuan et al.
Background: Hepatocellular carcinoma (HCC) develops and progresses via the RAF/MERK/ERK signaling pathway. Sorafenib, a first-line therapy for advanced HCC, inhibits the RAF gene. However, RAF dimerization and ERK activat...