Early growth response protein 1 regulates promoter activity of α-plasma membrane calcium ATPase 2, a major calcium pump in the brain and auditory system [0.03%]
早期生长反应蛋白1调节α-脑和听觉系统的主要钙泵PMCA2启动子活性
Rebecca R Minich,Jin Li,Bruce L Tempel
Rebecca R Minich
Background: Along with sodium/calcium (Ca2+) exchangers, plasma membrane Ca2+ ATPases (ATP2Bs) are main regulators of intracellular Ca2+ levels. There are four ATP2B paralogs encoded by four different genes. Atp2b2 encode...
Laura V Croft,Nicholas W Ashton,Nicolas Paquet et al.
Laura V Croft et al.
Background: Maintenance of genome stability is critical in human cells. Mutations in or loss of genome stability pathways can lead to a number of pathologies including cancer. hSSB1 is a critical DNA repair protein functi...
Selective measurement of α smooth muscle actin: why β-actin can not be used as a housekeeping gene when tissue fibrosis occurs [0.03%]
α平滑肌肌动蛋白的选择性测定：在组织纤维化发生时不能用β-肌动蛋白作为管家基因的原因
Apor Veres-Székely,Domonkos Pap,Erna Sziksz et al.
Apor Veres-Székely et al.
Background: Prevalence of fibroproliferative diseases, including chronic kidney disease is rapidly increasing and has become a major public health problem worldwide. Fibroproliferative diseases are characterized by increa...
Erratum to: RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions [0.03%]
RUNX1诱导SPI1调控区域独立于DNA复制的主动去甲基化错误予以更正
Shubham Goyal,Takahiro Suzuki,Jing-Ru Li et al.
Shubham Goyal et al.
Published Erratum
BMC molecular biology. 2017 Apr 21;18(1):11. DOI:10.1186/s12867-017-0088-x 2017
Identification of suitable reference genes for real-time quantitative PCR analysis of hydrogen peroxide-treated human umbilical vein endothelial cells [0.03%]
过氧化氢处理的人脐静脉内皮细胞实时定量PCR分析中适宜的参照基因的选择与鉴定
Tianyi Li,Hongying Diao,Lei Zhao et al.
Tianyi Li et al.
Background: Oxidative stress can induce cell injury in vascular endothelial cells, which is the initial event in the development of atherosclerosis. Although quantitative real-time polymerase chain reaction (qRT-PCR) has ...
RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions [0.03%]
RUNX1诱导SPI1调节区域独立于DNA复制的主动去甲基化
Shubham Goyal,Takahiro Suzuki,Jing-Ru Li et al.
Shubham Goyal et al.
Background: SPI1 is an essential transcription factor (TF) for the hematopoietic lineage, in which its expression is tightly controlled through a -17-kb upstream regulatory region and a promoter region. Both regulatory re...
Immunoglobulin T from sea bass (Dicentrarchus labrax L.): molecular characterization, tissue localization and expression after nodavirus infection [0.03%]
欧洲 seabass IgT的分子特性、组织定位及其感染结肠病毒后的表达特征分析
Francesco Buonocore,Valentina Stocchi,Noelia Nunez-Ortiz et al.
Francesco Buonocore et al.
Background: Immunoglobulins (Igs) are fundamental components of the adaptive immune system of vertebrates, with the IgT/IgZ isotype specific of Teleosts. In this paper we describe the identification of an IgT heavy chain ...
Methylated site display (MSD)-AFLP, a sensitive and affordable method for analysis of CpG methylation profiles [0.03%]
甲基化位点展示(MSD)-AFLP技术：一种敏感且经济的分析CpG甲基化谱型的方法
Toshiki Aiba,Toshiyuki Saito,Akiko Hayashi et al.
Toshiki Aiba et al.
Background: It has been pointed out that environmental factors or chemicals can cause diseases that are developmental in origin. To detect abnormal epigenetic alterations in DNA methylation, convenient and cost-effective ...
Properties of STAT1 and IRF1 enhancers and the influence of SNPs [0.03%]
STAT1和IRF1增强子的特性及其受到单核苷酸多态性的影响
Mohamed Abou El Hassan,Katherine Huang,Manoja B K Eswara et al.
Mohamed Abou El Hassan et al.
Background: STAT1 and IRF1 collaborate to induce interferon-γ (IFNγ) stimulated genes (ISGs), but the extent to which they act alone or together is unclear. The effect of single nucleotide polymorphisms (SNPs) on in viv...
Identification of microRNAs and their response to the stress of plant allelochemicals in Aphis gossypii (Hemiptera: Aphididae) [0.03%]
棉蚜microRNA的鉴定及其对植物化感物质胁迫的响应研究
Kang-Sheng Ma,Fen Li,Ying Liu et al.
Kang-Sheng Ma et al.
Background: MicroRNAs (miRNAs) are a group of short non-coding RNAs involved in the inhibition of protein translation or in mRNA degradation. Although the regulatory roles of miRNAs in various biological processes have be...