Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences [0.03%]
预测人类HLA-G基因蛋白异构体中最为有害的错义nsSNP并对其结构和功能影响进行计算机模拟评估
Elaheh Emadi,Fatemeh Akhoundi,Seyed Mehdi Kalantar et al.
Elaheh Emadi et al.
Background: The Human Leukocyte Antigen G (HLA-G) protein is an immune tolerogenic molecule with 7 isoforms. The change of expression level and some polymorphisms of the HLA-G gene are involved in various pathologies. The...
Characterization of bovine MHC DRB3 diversity in global cattle breeds, with a focus on cattle in Myanmar [0.03%]
全球牛种中牛MHC DRB3多态性的鉴定，重点关注缅甸的牛种
Guillermo Giovambattista,Kyaw Kyaw Moe,Meripet Polat et al.
Guillermo Giovambattista et al.
Background: Myanmar cattle populations predominantly consist of native cattle breeds (Pyer Sein and Shwe), characterized by their geographical location and coat color, and the Holstein-Friesian crossbreed, which is highly...
Transcriptomic and anatomic profiling reveal the germination process of different wheat varieties in response to waterlogging stress [0.03%]
转录组和解剖谱系分析揭示了不同小麦品种对水涝胁迫的发芽过程
Changwei Shen,Jingping Yuan,Hong Qiao et al.
Changwei Shen et al.
Background: Waterlogging is one of the most serious abiotic stresses affecting wheat-growing regions in China. Considerable differences in waterlogging tolerance have been found among different wheat varieties, and the me...
Microsatellite variation revealed panmictic pattern for Triatoma brasiliensis (Triatominae: Reduviidae) in rural northeastern Brazil: the control measures implications [0.03%]
微卫星变异表明巴西锥虫(Triatoma brasiliensis)在巴西东北部农村呈现泛混交模式：对控制措施的意义
Claudia Mendonça Bezerra,Carlota Josefovicz Belisário,Grasielle Caldas D&#x;Ávilla Pessoa et al.
Claudia Mendonça Bezerra et al.
Background: Triatoma brasiliensis Neiva, 1911 is the main vector of Trypanosoma cruzi in the caatinga of Northeastern Brazil. Despite of its epidemiological relevance, there are few studies on its genetic variability. Usi...
MCC-SP: a powerful integration method for identification of causal pathways from genetic variants to complex disease [0.03%]
MCC-SP：一种强大的整合方法，用于从遗传变异到复杂疾病的因果通路识别
Yuchen Zhu,Jiadong Ji,Weiqiang Lin et al.
Yuchen Zhu et al.
Background: Genome-wide association studies (GWAS) have successfully identified genetic susceptible variants for complex diseases. However, the underlying mechanism of such association remains largely unknown. Most diseas...
A 31-bp indel in the 5' UTR region of GNB1L is significantly associated with chicken body weight and carcass traits [0.03%]
GNB1L基因5'UTR区域的31-碱基对插入/删除与鸡体重要素和屠体性状显著相关
Tuanhui Ren,Ying Yang,Wujian Lin et al.
Tuanhui Ren et al.
Background: G-protein subunit beta 1 like (GNB1L) encodes a G-protein beta-subunit-like polypeptide. Chicken GNB1L is upregulated in the breast muscle of high feed efficiency chickens, and its expression is 1.52-fold that...
Identification and genetic analysis of EMS-mutagenized wheat mutants conferring lesion-mimic premature aging [0.03%]
EMS诱变小麦突变体的鉴定及其遗传分析发现该突变体具有模拟病斑早衰的表型
Weiwei Kong,Liming Wang,Pei Cao et al.
Weiwei Kong et al.
Background: Lesion-mimic and premature aging (lmpa) mutant lmpa1 was identified from the ethyl methane sulfonate (EMS) mutant library in the bread wheat variety Keda 527 (KD527) background. To reveal the genetic basis of ...
Phenotypic and molecular marker analysis uncovers the genetic diversity of the grass Stenotaphrum secundatum [0.03%]
表型和分子标记分析揭示了草类Stenotaphrum secundatum的遗传多样性
Ying Luo,Xiujie Zhang,Jiahong Xu et al.
Ying Luo et al.
Background: Stenotaphrum secundatum is an important grass with a rich variety of accessions and great potential for development as an economically valuable crop. However, little is known about the genetic diversity of S. ...
A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology [0.03%]
系统流行病学中识别差异特异路径的一种新型路径特异效应统计方法
Hongkai Li,Zhi Geng,Xiaoru Sun et al.
Hongkai Li et al.
Background: Biological pathways play an important role in the occurrence, development and recovery of complex diseases, such as cancers, which are multifactorial complex diseases that are generally caused by mutation of m...
Characterization of two MHC II genes (DOB, DRB) in white-tailed deer (Odocoileus virginianus) [0.03%]
白尾鹿(Odocoileus virginianus)的两个MHC II基因(DOB，DRB)的特征分析
Natascha M D Ivy-Israel,Carolyn E Moore,Tonia S Schwartz et al.
Natascha M D Ivy-Israel et al.
Background: The major histocompatibility complex (MHC) is responsible for detecting and addressing foreign pathogens inside the body. While the general structure of MHC genes is relatively well conserved among mammalian s...