mspms: an R package and GUI for multiplex substrate profiling by mass spectrometry [0.03%]
Mspms：一种用于多重底物谱分析的R包和GUI
Charlie Bayne,Brianna Hurysz,David J Gonzalez et al.
Charlie Bayne et al.
Background: Multiplex Substrate Profiling by Mass Spectrometry (MSP-MS) is a powerful method for determining the substrate specificity of proteolytic enzymes, which is essential for developing protease inhibitors, diagnos...
Identification of differentially expressed genes in RNA-seq data via semi-rigid orthogonal sparse KL-NMTF [0.03%]
基于半刚性正交稀疏KL-NMTF的RNA序数据中差异表达基因识别
Grazia Gargano,Flavia Esposito,Nicoletta Del Buono et al.
Grazia Gargano et al.
CNValidatron: accurate and efficient validation of PennCNV calls using computer vision [0.03%]
CNValidatr：利用计算机视觉准确而高效地验证PennCNV结果
Simone Montalbano,G Bragi Walters,Gudbjorn F Jonsson et al.
Simone Montalbano et al.
Background: Large, rare copy number variants (CNVs) are a main source of genetic variation in the genome and are important in both evolution and disease risk. CNVs can be detected using different data sources, including g...
zDUR: reference-free FASTQ compressor with high compression ratio and speed [0.03%]
具有高压缩比和速度的参考无关型FASTQ压缩器zDUR
Artem Ershov,Renpeng Ding,Qian Fu et al.
Artem Ershov et al.
Background: High-throughput sequencing technologies generate massive amounts of FASTQ data comprising nucleotide sequences, quality scores, and read identifiers, necessitating efficient compression to alleviate storage an...
A negative binomial latent factor model for paired microbiome sequencing data [0.03%]
配对微生物组测序数据的负二项隐含因子模型
Hyotae Kim,Nazema Y Siddiqui,Lisa Karstens et al.
Hyotae Kim et al.
Background: Microbiome sequencing data are often collected from several body sites and exhibit dependencies. Our objective is to develop a model that enables joint analysis of data from different sites by capturing the un...
QuAPPro: an R shiny app for quantification and alignment of polysome profiles [0.03%]
基于R语言的定量和多聚核糖体图谱比对工具QuAPPro应用程序
Chiara Schiller,Matthias Lemmer,Sonja Reitter et al.
Chiara Schiller et al.
Background: Polysome profiling is a widespread technique to study mRNA translation. After separation of cellular particles by ultracentrifugation on a sucrose-density gradient, a UV absorbance profile is recorded during e...
CRESCENT, a comprehensive RNA-Seq expression, splicing, and coding/non-coding element network tool [0.03%]
CRESCENT，一个综合性的RNA测序表达、剪接和编码/非编码元件网络工具
Gilles Sireta,Gwendal Cueff,Vincent Darbot et al.
Gilles Sireta et al.
Background: Traditional short-read RNA-Seq analysis pipelines predominantly focus on protein-coding genes, often overlooking other genomic sequences such as transposable elements (TEs) and non-coding RNA dynamics and do n...
Sebastian Raubach,Miriam Schreiber,Ruth Hamilton et al.
Sebastian Raubach et al.
Background: Accurate acquisition of phenotypic data is critical for cataloguing and utilising genetic variation in cultivated crops, landraces, and their wild relatives. The collection of phenotypic data using handwritten...
Mehmet Ali Balikci,Cyrille Mesue Njume,Ali Cakmak
Mehmet Ali Balikci
Biomarkers play a pivotal role in disease diagnosis and prognosis by offering molecular insights into biological states. The rapid growth of high-throughput omics technologies has enabled the generation of large-scale biomarker datasets, ye...
Violeta de Anca Prado,Fábio Pértille,Pedro Sá et al.
Violeta de Anca Prado et al.