Paula Ribeiro Lopes Almeida,Osmar C Person,Maria Es Puga et al.
Paula Ribeiro Lopes Almeida et al.
Background: Cystic fibrosis (CF) is a life-shortening, autosomal recessive disease that leads to abnormal electrolyte concentration in exocrine secretions. Secretion stasis in paranasal sinuses determines chronic rhinosin...
Bilal H Kirmani,Sion G Jones,Andrew Muir et al.
Bilal H Kirmani et al.
Background: Aortic valve disease is a common condition easily treatable with cardiac surgery. This is conventionally performed by opening the sternum ('median sternotomy') and replacing the valve under cardiopulmonary byp...
Inhaled corticosteroids with combination inhaled long-acting beta2-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease [0.03%]
长效β2受体激动剂及长效抗胆碱能药物联合吸入性糖皮质激素治疗慢性阻塞性肺疾病
Wouter H van Geffen,Daniel J Tan,Julia Ae Walters et al.
Wouter H van Geffen et al.
Background: Management of chronic obstructive pulmonary disease (COPD) commonly involves a combination of long-acting bronchodilators including beta2-agonists (LABA) and muscarinic antagonists (LAMA). LABA and LAMA bronch...
Interventions for improving coverage of childhood immunisation in low- and middle-income countries [0.03%]
提高中低收入国家儿童免疫覆盖率的干预措施
Angela Oyo-Ita,Olabisi Oduwole,Dachi Arikpo et al.
Angela Oyo-Ita et al.
Background: Immunisation plays a major role in reducing childhood morbidity and mortality. Getting children immunised against potentially fatal and debilitating vaccine-preventable diseases remains a challenge despite the...
Xin Jiang,Yanbo Li,Ning Chen et al.
Xin Jiang et al.
Background: Postherpetic neuralgia (PHN) is a common, serious, painful complication of herpes zoster. Corticosteroids have anti-inflammatory properties, and might be beneficial. This is an update of a review first publish...
Automated oxygen delivery for preterm infants with respiratory dysfunction [0.03%]
呼吸功能不全的早产儿的自动化吸氧疗法
Isabella G Stafford,Nai Ming Lai,Kenneth Tan
Isabella G Stafford
Background: Many preterm infants require respiratory support to maintain an optimal level of oxygenation, as oxygen levels both below and above the optimal range are associated with adverse outcomes. Optimal titration of ...
Adverse effects of immunotherapies for multiple sclerosis: a network meta-analysis [0.03%]
免疫疗法治疗多发性硬化不良反应的网状meta分析研究
Irene Tramacere,Gianni Virgili,Vittorio Perduca et al.
Irene Tramacere et al.
Background: Multiple sclerosis (MS) is a chronic disease of the central nervous system that affects mainly young adults (two to three times more frequently in women than in men) and causes significant disability after ons...
Progestogens for prevention of luteinising hormone (LH) surge in women undergoing controlled ovarian hyperstimulation as part of an assisted reproductive technology (ART) cycle [0.03%]
促黄体生成素释放激素类似物诱发卵泡期排卵以进行控制卵巢刺激和辅助生殖技术临床妊娠及活产结局的效果分析
Demián Glujovsky,Romina Pesce,Mariana Miguens et al.
Demián Glujovsky et al.
Background: Currently, gonadotrophin releasing hormone (GnRH) analogues are used to prevent premature ovulation in ART cycles. However, their costs remain high, the route of administration is invasive and has some adverse...
Background: Self-administered questionnaires are widely used to collect data in epidemiological research, but non-response reduces the effective sample size and can introduce bias. Finding ways to increase response to pos...
Nirmatrelvir combined with ritonavir for preventing and treating COVID-19 [0.03%]
奈玛特韦片联合利托那韦片用于防治新冠肺炎
Stefanie Reis,Maria-Inti Metzendorf,Rebecca Kuehn et al.
Stefanie Reis et al.
Background: Oral nirmatrelvir/ritonavir (Paxlovid) aims to avoid severe COVID-19 in asymptomatic people or those with mild symptoms, thereby decreasing hospitalization and death. It remains to be evaluated for which indic...